Recombinant Human Growth Factor Receptor-Bound Protein 7, GST-tagged GRB7-4848H

Recombinant Human Growth Factor Receptor-Bound Protein 7, GST-tagged

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Cat.No. : GRB7-4848H Optional Service: Optional requirements on this protein
Product Overview : Recombinant full-length human GRB7 was expressed by E.coli using an N-terminal GST tag.
Description : GRB7 or growth factor receptor-bound protein 7 belongs to a small family of adapter proteins which interact with a number of receptor tyrosine kinases and signaling molecules. GRB7 encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. GRB7 is highly expressed in liver and kidney. GRB7 isoforms are involved in cell invasion and metastatic progression of human esophageal carcinomas.
Applications : Western Blot
Molecular Weight : 91 kDa
Expression System : E. coli
Species : Human
Form : Recombinant protein stored in 50 mM Tris-HCl, PH 7.5, 150 mM NaCI, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Purity : >90%
Concentration : 0.2 ug/ul
Sequences : Full length
Storage : Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Pathways : Angiopoietin receptor Tie2-mediated signaling; Cell surface interactions at the vascular wall; Down-stream signal transduction; EGFR1 Signaling Pathway; EPHB forward signaling; Hemostasis; Kit Receptor Signaling Pathway; PDGFR-beta signaling pathway; Signaling by PDGF; Signaling events mediated by focal adhesion kinase; Signaling events regulated by Ret tyrosine kinase; Tie2 Signaling
PDBrendering based on 1mw4. :

Gene Name : GRB7 growth factor receptor-bound protein 7 [ Homo sapiens ]
Official Symbol : GRB7
Synonyms : GRB7; growth factor receptor-bound protein 7; growth factor receptor-bound protein 7; B47; OTTHUMP00000164349; OTTHUMP00000164350; OTTHUMP00000164351; OTTHUMP00000164352; GRB7 adapter protein; epidermal growth factor receptor GRB-7
Gene ID : 2886
mRNA Refseq : NM_001030002
Protein Refseq : NP_001025173
MIM : 601522
UniProt ID : Q14451
Chromosome Location : 17q12
Function : RNA binding; SH3/SH2 adaptor activity; lipid binding; phosphatidylinositol binding; protein binding; protein kinase binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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