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GTF2I

  • Official Full Name

    general transcription factor IIi

  • Overview

    GTF2l is required for the formation of functional ARID3A DNA-binding complexes and for activation of immunoglobulin heavy-chain transcription upon B-lymphocyte activation.
  • Synonyms

    GTF2I; general transcription factor IIi; general transcription factor II, i , WBSCR6; general transcription factor II-I; BAP 135; BTKAP1; DIWS; IB291; SPIN; TFII I; BTK-associated protein 135; BTK-associated protein, 135kD; SRF-Phox1-interacting protein; Williams-Beuren syndrome chromosome region 6; Bruton tyrosine kinase-associated protein 135; williams-Beuren syndrome chromosomal region 6 protein; WBS; BAP135; TFII-I; WBSCR6; GTFII-I; FLJ38776; FLJ56355;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GTF2I-4454H Recombinant Human GTF2I Protein, GST-tagged Wheat Germ GST
Human GTF2I-29513TH Recombinant Human GTF2I Wheat Germ N/A 239 amino acids
Human GTF2I-13601H Recombinant Human GTF2I, GST-tagged E.coli GST 1-274
Human GTF2I-29514TH Recombinant Human GTF2I Wheat Germ N/A 274 amino acids
Human GTF2I-763HCL Recombinant Human GTF2I cell lysate N/A
Human GTF2I-15H Recombinant Human GTF2I Protein (1-976), N-GST-tagged Wheat Germ N-GST 1-976
Human GTF2I-214HF Recombinant Full Length Human GTF2I Protein In Vitro Cell Free System 274 amino acids
Human GTF2I-3399HF Recombinant Full Length Human GTF2I Protein, GST-tagged In Vitro Cell Free System GST 274 amino acids
Mouse GTF2I-7363M Recombinant Mouse GTF2I Protein Mammalian Cell His
Mouse GTF2I-3993M-B Recombinant Mouse GTF2I Protein Pre-coupled Magnetic Beads HEK293
Mouse GTF2I-3993M Recombinant Mouse GTF2I Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GTF2I-2745R Recombinant Rat GTF2I Protein Mammalian Cell His
Rat GTF2I-2399R Recombinant Rat GTF2I Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GTF2I-2399R-B Recombinant Rat GTF2I Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque GTF2I-2010R Recombinant Rhesus monkey GTF2I Protein, His-tagged Mammalian Cell His
Rhesus Macaque GTF2I-1831R-B Recombinant Rhesus Macaque GTF2I Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque GTF2I-1831R Recombinant Rhesus Macaque GTF2I Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein

GTF2I involved in several pathways and played different roles in them. We selected most pathways GTF2I participated on our site, such as Basal transcription factors, cGMP-PKG signaling pathway, Herpes simplex infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF2I were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Basal transcription factorsTAF2;TAF8;GTF2H2;GTF2H2C;GTF2A2;TBPL2;MNAT1;GTF2H3;TBP
cGMP-PKG signaling pathwayCREB3L1;GNA11;KCNMB3;PPP1R12A;NPR2;GNAI1;PPP1CC;ATP1B1;INS
Herpes simplex infectionSRSF9;CCL5;HLA-DOA;PTPN11B;SRSF5;NXF3;ARNTL1B;TRAF6;C3A.2

GTF2I has several biochemical functions, for example, DNA binding, mitogen-activated protein kinase binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF2I itself. We selected most functions GTF2I had, and list some proteins which have the same functions with GTF2I. You can find most of the proteins on our site.

Function Related Protein
DNA bindingCHD9;SRFB;ZFP518A;ATOH7;SRFA;ZNF620;PURBA;SFPI1;MUS81
mitogen-activated protein kinase bindingTPR;ATF7;DUSP2;MAPKAPK2A;MAPKAPK2B;GTF2I;ABL1;PTPRJ;MAPKAPK5
protein bindingST6GAL1;SSR1;NR0B2;HIST1H2BE;Tnfrsf22;EYA2;TFIP11;YRDC;STARD3
transcription factor activity, sequence-specific DNA bindingFOXD3;IRF3;BCL3;ZNF256;GATAD2A;NPAS2;CNOT8;ZNF396;STAT2

GTF2I has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTF2I here. Most of them are supplied by our site. Hope this information will be useful for your research of GTF2I.

BTK; BRCA1; PTP4A3; Btk; NR4A2; MAGEA6; ARF6; NFKB2; USP7; OTUB2; GSTK1

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