Recombinant Human GTF2I Protein (1-976), N-GST-tagged

• Cat.No.: GTF2I-15H
• Product Overview: Human GTF2I full-length ORF ( AAH99907.1, 1 a.a.-976 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a phosphoprotein containing six characteristic repeat motifs. The encoded protein binds to the initiator element (Inr) and E-box element in promoters and functions as a regulator of transcription. This locus, along with several other neighboring genes, is deleted in Williams-Beuren syndrome. There are many closely related genes and pseudogenes for this gene on chromosome 7. This gene also has pseudogenes on chromosomes 9, 13, and 21. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
• Source: Wheat Germ
• Species: Human
• Tag: N-GST
• Molecular Mass: 136.5 kDa
• Protein Length: 1-976
• AA Sequence: MAQVAMSTLPVEDEESSESRMVVTF LMSALESMCKELAKSKAEVACIAVY ETDVFVVGTERGRAFVNTRKDFQKD FVKYCVEEEEKAAEMHKMKSTTQAN RMSVDAVEIETLRKTVEDYFCFCYG KALGKSTVVPVPYEKMLRDQSAVVV QGLPEGVAFKHPENYDLATLKWILE NKAGISFIIKRPFLEPKKHVGGRVM VTDADRSILSPGGSCGPIKVKTEPT EDSGISLEMAAVTVKEESEDPDYYQ YNIQGPSETDDVDEKQPLSKPLQGS HHSSEGNEGTEMEVPAEDDDYSPPS KRPKANELPQPPVPEPANAGKRKVR EFNFEKWNARITDLRKQVEELFERK YAQAIKAKGPVTIPYPLFQSHVEDL YVEGLPEGIPFRRPSTYGIPRLERI LLAKERIRFVIKKHELLNSTREDLQ LDKPASGVKEEWYARITKLRKMVDQ LFCKKFAEALGSTEAKAVPYQKFEA HPNDLYVEGLPENIPFRSPSWYGIP RLEKIIQVGNRIKFVIKRPELLTHS TTEVTQPRTNTPVKEDWNVRITKLR KQVEEIFNLKFAQALGLTEAVKVPY PVFESNPEFLYVEGLPEGIPFRSPT WFGIPRLERIVRGSNKIKFVVKKPE LVISYLPPGMASKINTKALQSPKRP RSPGSNSKVPEIEVTVEGPNNNNPQ TSAVRTPTQTNGSNVPFKPRGREFS FEAWNAKITDLKQKVENLFNEKCGE ALGLKQAVKVPFALFESFPEDFYVE GLPEGVPFRRPSTFGIPRLEKILRN KAKIKFIIKKPEMFETAIKESTSSK SPPRKINSSPNVNTTASGVEDLNII QVTIPDDDNERLSKVEKARQLREQV NDLFSRKFGEAIGMGFPVKVPYRKI TINRGCVVVDGMPPGVSFKAPSYLE ISSMRRILDSAEFIKFTVIRPFPGL VVNNQLVDQSESEGPVIQESAEPSQ LEVPATEEIKETDGSSQIKQEPDPT W
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GTF2I general transcription factor IIi [ Homo sapiens (human) ]
• Official Symbol: GTF2I
• Synonyms: GTF2I; general transcription factor IIi; WBS; DIWS; SPIN; IB291; BAP135; BTKAP1; TFII-I; WBSCR6; GTFII-I; general transcription factor II-I; BTK-associated protein, 135kD; Bruton tyrosine kinase-associated protein 135; SRF-Phox1-interacting protein; Williams-Beuren syndrome chromosome region 6
• Gene ID: 2969
• mRNA Refseq: NM_001518
• Protein Refseq: NP_001509
• MIM: 601679
• UniProt ID: P78347