GUCY2C
-
Official Full Name
guanylate cyclase 2C (heat stable enterotoxin receptor)
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Canine
- Cynomolgus
- Cynomolgus monkey
- Human
- Mouse
- Rat
- E.coli
- HEK293
- Insect Cell
- Insect Cells
- Wheat Germ
- Yeast
- C
- His
- Fc
- Avi
- GST
- Myc
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
GUCY2C involved in several pathways and played different roles in them. We selected most pathways GUCY2C participated on our site, such as Purine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with GUCY2C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Purine metabolism | POLR2E;GUCY1B3;POLR3A;PKM2;NME1-NME2;NT5C3A;APRT;GUK1A;HPRT1 |
GUCY2C has several biochemical functions, for example, ATP binding, GTP binding, NOT adenylate cyclase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GUCY2C itself. We selected most functions GUCY2C had, and list some proteins which have the same functions with GUCY2C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | EPHB4;GSG2;RTCB;KDR;GLULB;DARS;MAPK15;CAMK2D1;AURKA |
| GTP binding | EEF1A1;GBP6;RAB21;ARF3B;INSR;EFTUD1;RABL2A;GNAO1A;RAB2A |
| NOT adenylate cyclase activity | NPR1;GUCY2F;GUCY2C;GUCY1A3;NPR3;GC2;GUCY1B3;NPR1A;NPR2 |
| guanylate cyclase activity | NPR2;NPR1;GUCY1A3;GUCY2E;GC3;GUCY2F;GC2;NPR1A;GUCY2C |
| protein binding | ZNF2;NUP85;HPSE;LCE3C;RNF165;ZFP932;RAPGEF3;SMARCB1;CCNB1 |
| protein kinase activity | RPS6KA6;MAP3K3;BMPR2B;CASKB;CDC42BPB;CCND1;MAP3K1;GSK3AA;EPHA4B |
| toxic substance binding | AZU1;H2-AB1;NEFH;Alb;GUCY2C;EPHX2;ASS1;DSG1;PHAX |
GUCY2C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GUCY2C here. Most of them are supplied by our site. Hope this information will be useful for your research of GUCY2C.
PDZD3; PDZK1; alsS
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewNo complaints, worked well.
Perfect for protein assays.
Consistent quality, great results.
Q&As (7)
Ask a questionIt regulates ion and water balance in intestinal cells, influencing fluid secretion.
Therapeutic strategies include GUCY2C agonists for constipation and its use as a target in colorectal cancer immunotherapy.
GUCY2C acts as a tumor suppressor; its loss or mutation is linked to colorectal cancer.
GUCY2C expression and activity are regulated by various signaling pathways and post-translational modifications.
GUCY2C produces cyclic GMP in response to ligand binding, modulating cellular functions.
It maintains the intestinal barrier, protecting against pathogens and inflammation.
GUCY2C is predominantly expressed in the intestinal epithelium.
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