Recombinant Human GUCY2C protein, His-Avi-tagged

• Cat.No.: GUCY2C-092H
• Product Overview: Recombinant human Guanylyl Cyclase C/GUCY2C Protein is expressed from mammalian with a His Tag and Avi Tag at the C-terminal. It contains Ser24-Gln430.

Specification

• Description: Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy.
• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 48.8 kDa.Due to glycosylation, the protein migrates to 70-90 KDa based on Bis-Tris PAGE result.
• Protein length: Ser24-Gln430
• Endotoxin: Less than 0.05 EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: GUCY2C
• Official Symbol: GUCY2C
• Synonyms: STA receptor, Hstar, GC-C, GUC2C, STAR
• Gene ID: 2984
• mRNA Refseq: NM_004963.4
• Protein Refseq: NP_004954.2
• MIM: 601330
• UniProt ID: P25092