Recombinant Human GUCY2C Protein, GST-tagged

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Recombinant Human GUCY2C Protein, GST-tagged

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Cat.No. : GUCY2C-4492H
Product Overview : Human GUCY2C partial ORF ( NP_004954, 24 a.a. - 133 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive). [provided by RefSeq, Nov 2016]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 37.73 kDa
AA Sequence : SQVSQNCHNG SYEISVLMMG NSAFAEPLKN LEDAVNEGLE IVRGRLQNAG LNVTVNATFM YSDGLIHNSG DCRSSTCEGL DLLRKISNAQ RMGCVLIGPS CTYSTFQMYL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : GUCY2C guanylate cyclase 2C (heat stable enterotoxin receptor) [ Homo sapiens ]
Official Symbol : GUCY2C
Synonyms : GUCY2C; guanylate cyclase 2C (heat stable enterotoxin receptor); GUC2C; heat-stable enterotoxin receptor; STAR; GC-C; hSTAR; STA receptor; guanylyl cyclase C; intestinal guanylate cyclase;
Gene ID : 2984
mRNA Refseq : NM_004963
Protein Refseq : NP_004954
MIM : 601330
UniProt ID : P25092

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