Recombinant Human GUCY2C Protein, His-tagged

• Cat.No.: GUCY2C-01H
• Product Overview: Recombinant Human GUCY2C Protein, fused to His-tag, was expressed in Human cells.

Specification

• Description: This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive).
• Source: Human cells
• Species: Human
• Tag: His
• Form: Supplied as a 0.2 μm filtered solution in PBS (pH 7.4).
• AA Sequence: SQVSQNCHNGSYEISVLMMGNSAFA EPLKNLEDAVNEGLEIVRGRLQNAG LNVTVNATFMYSDGLIHNSGDCRSS TCEGLDLLRKISNAQRMGCVLIGPS CTYSTFQMYLDTELSYPMISAGSFG LSCDYKETLTRLMSPARKLMYFLVN FWKTNDLPFKTYSWSTSYVYKNGTE TEDCFWYLNALEASVSYFSHELGFK VVLRQDKEFQDILMDHNRKSNVIIM CGGPEFLYKLKGDRAVAEDIVIILV DLFNDQYFEDNVTAPDYMKNVLVLT LSPGNSLLNSSFSRNLSPTKRDFAL AYLNGILLFGHMLKIFLENGENITT PKFAHAFRNLTFEGYDGPVTLDDWG DVDSTMVLLYTSVDTKKYKVLLTYD THVNKTYPVDMSPTFTWKNSKLPND ITGRGPQHHHHHHHHHH
• Endotoxin: <1.0EU per 1ml (determined by the LAL method)
• Purity: >90%, by SDS-PAGE
• Storage: Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 1.0 mg/ml

Gene Information

• Gene Name: GUCY2C guanylate cyclase 2C [ Homo sapiens (human) ]
• Official Symbol: GUCY2C
• Synonyms: GCC; GC-C; HSER; STAR; DIAR6; GUC2C; MECIL; MUCIL
• Gene ID: 2984
• mRNA Refseq: NM_004963.4
• Protein Refseq: NP_004954.2
• MIM: 601330
• UniProt ID: P25092