Recombinant Rat GUCY2C Protein (23-429 aa), His-Myc-tagged

• Cat.No.: GUCY2C-2763R
• Product Overview: Recombinant Rat GUCY2C Protein (23-429 aa) is produced by Baculovirus expression system. This protein is fused with a 10xHis tag at the N-terminal and a Myc tag at the C-terminal. Research Area: Microbiology. Protein Description: Partial.

Specification

• Description: Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptide guanylin.
• Source: Baculovirus
• Species: Rat
• Tag: His-Myc
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 50.4 kDa
• Protein length: 23-429 aa
• AA Sequence: SQVRQKCHNGTYEISVLMMDNSAYK EPLQNLRDAVEEGLDIVRKRLREAE LNVTVNATFIYSDGLIHKSGDCRSS TCEGLDLLREITRDRKMGCVLMGPS CTYSTFQMYLDTELNYPMISAGSFG LSCDYKETLTRILPPARKLMYFLVD FWKVNNAPFKTFSWNSSYVYKNGSE PEDCFWYLNALEAGVSYFSEVLSFK DVLRRSEQFQEILMGRNRKSNVIVM CGTPETFYNVKGDLKVADDTVVILV DLFSNHYFEDDTRAPEYMDNVLVLT LPPEKFIANASVSGRFPSERSDFSL AYLEGTLLFGHMLQTFLENGESVTT PKFARAFRNLTFQGLEGPVTLDDSG DIDNIMCLLYVSLDTRKYKVLMAYD THKNQTIPVATSPNFIWKNHRLPND VPGLGPQ
• Purity: > 85% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.

Gene Information

• Gene Name: Gucy2c guanylate cyclase 2C [ Rattus norvegicus ]
• Official Symbol: GUCY2C
• Synonyms: GUCY2C; guanylate cyclase 2C; heat-stable enterotoxin receptor; GC-C; STA receptor; guanylyl cyclase C; GCC
• Gene ID: 25711
• mRNA Refseq: NM_013170
• Protein Refseq: NP_037302
• UniProt ID: P23897