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Official Full Name heme oxygenase (decycling) 1
Background Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.
Synonyms 32 kD; bK286B10; D8Wsu38e; heat shock protein 32 kD; heat shock protein 32kD; Heat shock protein; Heme oxygenase (decycling) 1; Heme oxygenase 1; Hemox; HMOX 1; Hmox; HMOX1; HMOX1_HUMAN; HO 1; HO; HO-1; HO1; Hsp32
    • Species :
    • Cattle
    • Chicken
    • Human
    • Mouse
    • Pig
    • Rat
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Yeast
    • Tag :
    • GST
    • His
    • MBP
    • S
    • T7
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HMOX1-061H Recombinant Human HMOX1 Protein, His-tagged E. coli His
    Human HMOX1-023H Recombinant Human HMOX1 Protein, His-tagged E.coli His
    Human HMOX1-137H Recombinant Human Heme Oxygenase 1, His-tagged E.coli His
    Human HMOX1-138H Recombinant Human HMOX1 protein, His-tagged E.coli His
    Human HMOX1-1556H Recombinant Human HMOX1 protein, His-tagged E.coli His
    Human HMOX1-1597H Recombinant Human Heme Oxygenase (decycling) 1, GST-tagged E.coli GST
    Human HMOX1-2604H Recombinant Human HMOX1 protein, His & S-tagged E.coli His/S
    Human HMOX1-27002TH Recombinant Human HMOX1 E.coli N/A
    Human HMOX1-277H Recombinant Human HMOX1 protein, His/MBP-tagged E.coli His/MBP
    Human HMOX1-27877TH Recombinant Human HMOX1, His-tagged E.coli His
    Human HMOX1-4884H Recombinant Human HMOX1 Protein, GST-tagged Wheat Germ GST
    Human HMOX1-5467HCL Recombinant Human HMOX1 293 Cell Lysate HEK293 N/A
    Human HMOX1-5723H Recombinant Human HMOX1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Hmox1-1141M Recombinant Mouse Hmox1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Mouse HMOX1-1412M Recombinant Mouse HMOX1 Protein (1-289 aa), His-tagged Yeast His
    Mouse Hmox1-2605M Recombinant Mouse Hmox1 protein, His & S-tagged E.coli His/S
    Mouse HMOX1-7743M Recombinant Mouse HMOX1 Protein Mammalian Cell His
    Rat Hmox1-1557R Recombinant Rat Hmox1 protein, His-tagged E.coli His
    Rat HMOX1-2493R Recombinant Rat HMOX1 Protein (1-289 aa), His-tagged Yeast His
    Rat HMOX1-2872R Recombinant Rat HMOX1 Protein Mammalian Cell His
    Rat Hmox1-31R Recombinant Rat Hmox1, His-tagged E.coli His
    Rat Hmox1-32R Recombinant Rat Hmox1 protein, His-tagged E.coli His
    Rat Hmox1-716R Recombinant Rat Heme Oxygenase (Decycling) 1 E.coli N/A
    Chicken HMOX1-6896C Recombinant Chicken HMOX1 Mammalian Cell His
    Cattle HMOX1-2603C Recombinant Cattle HMOX1 protein, His & T7-tagged E.coli His/T7
    Pig HMOX1-2606P Recombinant Pig HMOX1 protein, His & S-tagged E.coli His/S
    Pig HMOX1-2607P Recombinant Pig HMOX1 protein, His & GST-tagged E.coli His/GST

    hmox1 involved in several pathways and played different roles in them. We selected most pathways hmox1 participated on our site, such as Porphyrin and chlorophyll metabolism, HIF- signaling pathway, Mineral absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with hmox1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Porphyrin and chlorophyll metabolism EPRS; HMOX2; UGT2A1; CP; UGT1A6A; UGT2B7; UROD; UGT1A6B; UGT1A7C; FXN
    HIF- signaling pathway PIK3CA; PFKFB3; INS2; RBX1; PIK3R2; PIK3R1; HK2; PIK3CB; AKT1; RELA
    Mineral absorption MT1M; HMOX1; ATP1B1; MT1; MT1X; STEAP2; SLC8A1; SLC31A1; HMOX2; ATP1A3
    MicroRNAs in cancer BCL2L2; PDGFRB; IGF2BP1; PIM1; NRAS; IKBKB; CDC25C; PLCG2; TNR; NOTCH4

    hmox1 has several biochemical functions, for example, enzyme binding, heme binding, heme oxygenase (decyclizing) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by hmox1 itself. We selected most functions hmox1 had, and list some proteins which have the same functions with hmox1. You can find most of the proteins on our site.

    Function Related Protein
    enzyme binding GSTM7; PDE4D; PLAUR; NOXO1; HDAC1; LYN; ITGB3; SLC18A1; HMOX1; GBP1
    heme binding CYB5R4; PTGES2; HBAE1; CYP2C39; NOS2; NOS1; CYP4X1; HBBE2; CYP4F14; CYP46A1.3
    heme oxygenase (decyclizing) activity HMOX1A; HMOX2; HMOX1B; HMOX2A; HMOX1
    metal ion binding ZDHHC18A; ACSM5; CCDC76; GRIN2A; FTR82; ARFGAP1; ASPA; ZFYVE21; ADNP2B; CYP2X10.2
    phospholipase D activity PLD2; PLD3; PLD4; PLD1A; PLD1; GPLD1; HMOX1
    protein binding HSPBP1; PCMT1; TRAF4; ALG13; CD59; PPM1K; DIEXF; ESR2; GAGE8; BARD1
    protein homodimerization activity DGCR8; HMGCS1; NUDT21; UPK1A; ATG7; DMRTC1B; VPS25; SETMAR; PDE2A; SNRPC
    signal transducer activity GPR62; IRS1; TRAF5; VMN1R43; OLFR18; GPR82; TAAR14J; DRD4-RS; RRH; PROKR1A

    hmox1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with hmox1 here. Most of them are supplied by our site. Hope this information will be useful for your research of hmox1.

    POT1; CREB3; ASL; TERF1; proS; q7ckk6_yerpe; hemL2; comEA; yvaE; gcvP

    Muhsain, SNF; Lang, MA; et al. Mitochondrial targeting of bilirubin regulatory enzymes: An adaptive response to oxidative stress. TOXICOLOGY AND APPLIED PHARMACOLOGY 282:77-89(2015).
    Repesse, Y; Peyron, I; et al. Development of inhibitory antibodies to therapeutic factor VIII in severe hemophilia A is associated with microsatellite polymorphisms in the HMOX1 promoter. HAEMATOLOGICA 98:1650-1655(2013).

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