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Recombinant Mouse HMOX1 Protein (1-289 aa), His-tagged

Cat.No. : HMOX1-1412M
Product Overview : Recombinant Mouse HMOX1 Protein (1-289 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Protein Description: Full Length.
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  • Gene Information
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Description : He oxygenase cleaves the he ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of he oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free he sensitizes cells to undergo apoptosis.
Source : Yeast
Species : Mouse
Tag : His
Form : Tris-based buffer,50% glycerol
Molecular Mass : 34.9 kDa
Protein length : 1-289 aa
AA Sequence : MERPQPDSMPQDLSEALKEATKEVH IQAENAEFMKNFQKGQVSREGFKLV MASLYHIYTALEEEIERNKQNPVYA PLYFPEELHRRAALEQDMAFWYGPH WQEIIPCTPATQHYVKRLHEVGRTH PELLVAHAYTRYLGDLSGGQVLKKI AQKAMALPSSGEGLAFFTFPNIDSP TKFKQLYRARMNTLEMTPEVKHRVT EEAKTAFLLNIELFEELQVMLTEEH KDQSPSQMASLRQRPASLVQDTAPA ETPRGKPQISTSSSQTPLLQWVLTL SFLLATVAVGIYAM
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products.
Gene Name : Hmox1 heme oxygenase (decycling) 1 [ Mus musculus ]
Official Symbol : HMOX1
Synonyms : HMOX1; P32 protein; HO1; HO-1; Hmox; Hemox; Hsp32; D8Wsu38e;
Gene ID : 15368
mRNA Refseq : NM_010442
Protein Refseq : NP_034572
UniProt ID : P14901

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can you discuss the role of HMOX1 in modulating the immune response in the context of infectious diseases, and how its induction may impact host-pathogen interactions? 03/02/2022

HMOX1 modulates the immune response during infectious diseases, influencing host-pathogen interactions. Its induction can contribute to an anti-inflammatory environment and impact the outcome of infections.

How does HMOX1 contribute to the regulation of iron homeostasis, and what are the molecular mechanisms involved in its interaction with iron-responsive elements? 06/10/2020

HMOX1 regulates iron homeostasis by releasing free iron during heme degradation. Its interaction with iron-responsive elements influences cellular iron levels and responses to iron availability.

What is the relationship between HMOX1 and oxidative stress-induced autophagy, and how does this connection influence cellular responses to stressors? 01/23/2019

HMOX1 is linked to oxidative stress-induced autophagy, contributing to cellular adaptation and survival. This connection influences the cellular response to stressors by promoting self-cleaning mechanisms.

Can you discuss the role of HMOX1 in vascular health and its impact on endothelial function, particularly in the context of cardiovascular diseases? 12/18/2018

HMOX1 plays a role in vascular health by protecting endothelial cells. Its anti-inflammatory and vasodilatory effects contribute to cardiovascular protection and may have implications for disease prevention.

How does HMOX1 participate in the modulation of the immune response, and what are the mechanisms by which it influences inflammatory pathways? 10/14/2018

HMOX1 modulates the immune response by suppressing inflammation. It inhibits pro-inflammatory pathways by influencing transcription factors and inhibiting the production of inflammatory mediators.

Customer Reviews (3)

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Reviews
10/03/2021

    A reliable source for top-notch proteins. Fast shipping is a big plus.

    04/14/2020

      Exceptional service! This product has become a staple in our lab.

      09/30/2018

        Impressed with the product's quality. Shipping is always on time.

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