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Official Full Name IFI30 interferon, gamma-inducible protein 30 [ Homo sapiens ]
Background The protein encoded by this gene is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. This enzyme has an important role in MHC class II-restricted antigen processing.
Synonyms interferon, gamma-inducible protein 30; 5398; Ensembl:ENSG00000216490; MGC32056; gamma-interferon-inducible lysosomal thiol reductase; legumaturain; gamma-interferon-inducible protein IP-30; interferon gamma-inducible protein 30 preproprotein; GILT; IP30; IFI-30
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • T7
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IFI30-1317H Recombinant Human IFI30 protein, His & T7-tagged E.coli His/T7
    Human IFI30-14061H Recombinant Human IFI30, GST-tagged E.coli GST
    Human IFI30-1503HCL Recombinant Human IFI30 cell lysate Human Cell N/A
    Human IFI30-468H Recombinant Human IFI30 Protein, His-tagged HEK293 His
    Human IFI30-7185H Recombinant Human Interferon, Gamma-Inducible Protein 30, His-tagged E.coli His
    Human IFI30-755H Recombinant Human IFI30 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human IFI30-991H Recombinant Human IFI30 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Mouse Ifi30-3476M Recombinant Mouse Ifi30 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse IFI30-8009M Recombinant Mouse IFI30 Protein Mammalian Cell His
    Rat IFI30-2993R Recombinant Rat IFI30 Protein Mammalian Cell His
    Zebrafish IFI30-1567Z Recombinant Zebrafish IFI30 Mammalian Cell His

    ifi30 involved in several pathways and played different roles in them. We selected most pathways ifi30 participated on our site, such as Adaptive Immune System, Antigen processing and presentation, Cytokine Signaling in Immune system, which may be useful for your reference. Also, other proteins which involved in the same pathway with ifi30 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System AP2S1; NCR3LG1; MGC174857; RNF19B; ASB10; FRS2; LILRA3; UBE2E3; SEC23A; KIFAP3
    Antigen processing and presentation HLA-DQA2; CD74; CD8B1; HLA-DOB; CD8B; KIR2DL1; HSPA2; CD4; KLRC2; HLA-F
    Cytokine Signaling in Immune system FGF18B; XAF1; KPNA5; SPNA1; MX2; EIF4G2; HLA-DQB2; DUSP10; FRS2; IRAK3
    Immune System PVRL2L; CD300E; LILRA3; CD300LF; KLRB1A; ARIH2; LILRB1; DYNLL2; Mill2; DEFB1
    Interferon Signaling TRIM31; TRIM22; TRIM14; XAF1; ISG20; GBP6; TRIM26; SAMHD1; ARIH1L; TRIM38
    Interferon gamma signaling OASL; IRF6; TRIM5; TRIM17; GBP6; GBP4; TRIM46; TRIM22; TRIM45; TRIM48
    MHC class II antigen presentation AP1S3A; MGC174857; KIFAP3; KIF3B; MGC174152; KIF26A; CTSH; DYNC1LI2; ACTR1B; CTS7

    ifi30 has several biochemical functions, for example, oxidoreductase activity, acting on a sulfur group of donors, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ifi30 itself. We selected most functions ifi30 had, and list some proteins which have the same functions with ifi30. You can find most of the proteins on our site.

    Function Related Protein
    oxidoreductase activity, acting on a sulfur group of donors SRX1; IFI30
    protein binding CHMP1A; CDK1; AXIN2; CTAG1A; VPREB1; ERGIC2; CLK1; NUSAP1; DSP; DVL3

    ifi30 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ifi30 here. Most of them are supplied by our site. Hope this information will be useful for your research of ifi30.

    NOTCH2NL; KRTAP4-12; mutT7; DAPK1; Cnot2; KIFAP3; Sept6

    Cheluvappa, R; Eri, R; et al. Modulation of Interferon Activity-Associated Soluble Molecules by Appendicitis and Appendectomy Limits Colitis-Identification of Novel Anti-Colitic Targets. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH 35:108-115(2015).
    Metsalu, T; Viltrop, T; et al. Using RNA sequencing for identifying gene imprinting and random monoallelic expression in human placenta. EPIGENETICS 9:1397-1409(2014).

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