• Official Full Name

    interleukin 36 receptor antagonist

  • Background

    The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine was shown to specifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding the same protein have been reported.
  • Synonyms

    IL36RN; interleukin 36 receptor antagonist; IL1F5, interleukin 1 family, member 5 (delta); interleukin-36 receptor antagonist protein; family of interleukin 1 delta; FIL1; FIL1(DELTA); FIL1D; IL 1 related protein 3; IL 1F5; IL1HY1; IL1L1; IL1RP3; IL36RA; IL1F5; PSORP;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • GMP Proteins
    • Species :
    • Bovine
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human cells
    • Human Cells
    • In Vitro Cell Free System
    • Wheat Germ
    • Yeast
    • Tag :
    • Fc
    • GST
    • His
    • His(C
    • ter)
    • His|T7
    • SUMO
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Bovine IL1F5-237B Recombinant Bovine Interleukin 1 Family, Member 5 (Delta) Yeast N/A
    Human IL36RN-596H Recombinant Human interleukin 36 receptor antagonist, His-tagged E.coli His
    Human IL36RN-512H Recombinant Human IL36RN protein E.coli N/A
    Human IL36RN-5240HCL Recombinant Human IL1F5 293 Cell Lysate HEK293 N/A
    Human IL36RN-5239HCL Recombinant Human IL1F5 293 Cell Lysate HEK293 N/A
    Human IL36RN-169HG GMP Recombinant Human IL36RN protein, Fc-tagged HEK293 Fc
    Human IL36RN-5185H Recombinant Human IL36RN Protein, GST-tagged Wheat Germ GST
    Human IL36RN-5462H Recombinant Human IL36RN Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human IL1F5-14169H Recombinant Human IL1F5, His-tagged E.coli His
    Human IL36RN-4809H Recombinant Human IL36RN protein, His-SUMO-tagged E.coli His-SUMO
    Human IL36RN-5660H Active Recombinant Human Interleukin 36 Receptor Antagonist E.coli N/A
    Human IL36RN-151H Recombinant Human IL36RN Protein, His-tagged Human Cells His
    Human IL36RN-2009H Recombinant Human IL36RN Protein, His-tagged E.coli His
    Human IL36RN-5788HF Recombinant Full Length Human IL36RN Protein, GST-tagged In Vitro Cell Free System GST
    Human IL36RN-2553H Recombinant Human IL36RN Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human IL36RN-200H Recombinant Active Human IL36RN Protein, His-tagged(C-ter) E.coli His(C-ter)
    Human IL36RN-152H Recombinant Human IL36RN Protein, His-tagged Human cells His
    Mouse Il36rn-3505M Recombinant Mouse Il36rn Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse Il1f5-553M Recombinant Mouse Il1f5 protein E.coli N/A
    Mouse Il1f5-148M Recombinant Mouse Il1f5 Protein E.coli
    Mouse Il36rn-01M Active Recombinant Mouse Il36rn Protein, His-Tagged E.coli His
    Mouse Il1f5-307M Recombinant Mouse Il1f5, None tagged E.coli N/A
    Mouse Il1f5-2836M Recombinant Mouse Il1f5 protein, His & T7-tagged E.coli His/T7
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • IL36RN Related Gene Family
    • IL36RN Related Research Area

    IL36RN involved in several pathways and played different roles in them. We selected most pathways IL36RN participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IL36RN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    IL36RN has several biochemical functions, for example, cytokine activity, interleukin-1 receptor antagonist activity, interleukin-1 receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL36RN itself. We selected most functions IL36RN had, and list some proteins which have the same functions with IL36RN. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activityIL6;IL22;IFNA8;CSF1B;Il23a; Il12b;TNFSF4;IL37;CMTM4;CCL20A.3
    interleukin-1 receptor antagonist activityIL1RN;Il1f5;IL36RN
    interleukin-1 receptor bindingTLR9;IRAK4;IL1RAP;IL1F10;IL1B;IL36RN;IRAK1;IL37;IL36G
    protein bindingTEAD3;UBASH3B;KRT6B;TFF2;NOX1;CHRNA5;MB21D2;SPDYE2;EIF1AY

    IL36RN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL36RN here. Most of them are supplied by our site. Hope this information will be useful for your research of IL36RN.


    • Q&As
    • Reviews

    Q&As (6)

    Ask a question
    What is the action mechanism of IL36RN? 06/11/2022

    The mechanism of action of IL36RN is to play an anti-inflammatory, anti-infection, anti-tumor and other biological mechanisms by acting on the signaling pathway of IL-36 receptor.

    How to ensure the purity of IL36RN when preparing it? 11/22/2021

    The purity of IL36RN can be ensured by ion exchange chromatography, dialysis, gel filtration and other methods.

    IL36RN production process is what? 03/24/2020

    Mass production of IL36RN can be carried out through large-scale fermentation, purification and other processes.

    What is the difference between IL36RN protein and IL36α, β, γ? 03/22/2020

    This protein is an inhibitor with no biological activity of its own; Recombinant IL36α, β and γ are agonists with different biological effects.

    Can recombinant IL36RN be used in clinical trials and therapeutics? 09/24/2019

    Can be used in clinical trials and therapy.

    Does IL36RN have sustained and stable biological activity? 03/24/2019

    IL36RN has sustained and stable biological activity.

    Customer Reviews (3)

    Write a review

      This protein is involved in the regulation of immune response, especially in the body's response to bacterial and viral infections, it can inhibit the activation of inflammatory cells and the release of inflammatory factors. -


        IL-36Ra is able to inhibit IL-36-mediated signaling by binding to IL-36 receptors, and thus has biological activity to regulate immunity and anti-inflammatory effects. -


          It is a soluble protein that is easy to manipulate in vitro studies and applications. -

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