Active GMP Recombinant Human IL36RN protein, Fc-tagged

• Cat.No.: IL36RN-169HG
• Product Overview: GMP Recombinant Human IL36RN protein(NP_036407.1)(392 aa), fused with Fc Tag at the C-terminal, was expressed in HEK293 cell in an animal component free process under cGMP guidelines.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Protein Length: DNA sequence encoding Human IL-36RA(NP_036407.1) was expressed with Fc tag at the C-terminal.
• Bio-activity: The ability to inhibit the secretion of IL-8 by A431 cells under the action of IL-36γ was used for determination. When the concentration of IL-36β is 10ng/mL, the ED50 of this effect is 0.2-1ug/mL
• Molecular Mass: Recombinant Human IL-36RA contains 392 aa. It has a predicted MW of 43.8 kDa.
• Endotoxin: <=0.01EU/ug
• Purity: >=95% by SDS-PAGE and HPLC
• Storage: The lyophilized preparation can be stored at 4°C for 24 months, and the dissolved liquid can be stored at -20°C for 6-12 months to avoid repeated freezing and thawing
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: IL36RN interleukin 36 receptor antagonist [ Homo sapiens (human) ]
• Official Symbol: IL36RN
• Synonyms: FIL1; FIL1D; IL1F5; IL1L1; PSORP; IL1HY1; IL1RP3; IL36RA; IL-36Ra; PSORS14; FIL1(DELTA)
• Gene ID: 26525
• mRNA Refseq: NM_012275.3
• Protein Refseq: NP_036407.1
• MIM: 605507
• UniProt ID: Q9UBH0