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Recombinant Full Length Human IL36RN Protein, GST-tagged

Cat.No. : IL36RN-5788HF
Product Overview : Human IL36RN full-length ORF ( NP_036407.1, 1 a.a. - 155 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine was shown to specifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq
Source : In Vitro Cell Free System
Species : Human
Tag : GST
Molecular Mass : 43.4 kDa
Protein Length : 155 amino acids
AA Sequence : MVLSGALCFRMKDSALKVLYLHNNQ LLAGGLHAGKVIKGEEISVVPNRWL DASLSPVILGVQGGSQCLSCGVGQE PTLTLEPVNIMELYLGAKESKSFTF YRRDMGLTSSFESAAYPGWFLCTVP EADQPVRLTQLPENGGWNAPITDFY FQQCD
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : IL36RN interleukin 36 receptor antagonist [ Homo sapiens ]
Official Symbol : IL36RN
Synonyms : IL36RN; interleukin 36 receptor antagonist; IL1F5, interleukin 1 family, member 5 (delta); interleukin-36 receptor antagonist protein; family of interleukin 1 delta; FIL1; FIL1(DELTA); FIL1D; IL 1 related protein 3; IL 1F5; IL1HY1; IL1L1; IL1RP3; IL36RA; interleukin 1 HY1; interleukin 1 receptor antagonist homolog 1; MGC29840; IL-1ra homolog 1; interleukin-1 HY1; IL-1 related protein 3; interleukin-1-like protein 1; family of interleukin 1-delta; IL1F5 (Canonical product IL-1F5a); interleukin 1 family, member 5 (delta); interleukin-1 receptor antagonist homolog 1; IL-1F5 (IL-1HY1, FIL1-delta, IL-1RP3, IL-1L1, IL-1-delta); IL1F5; PSORP;
Gene ID : 26525
mRNA Refseq : NM_012275
Protein Refseq : NP_036407
MIM : 605507
UniProt ID : Q9UBH0

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the action mechanism of IL36RN? 06/11/2022

The mechanism of action of IL36RN is to play an anti-inflammatory, anti-infection, anti-tumor and other biological mechanisms by acting on the signaling pathway of IL-36 receptor.

How to ensure the purity of IL36RN when preparing it? 11/22/2021

The purity of IL36RN can be ensured by ion exchange chromatography, dialysis, gel filtration and other methods.

IL36RN production process is what? 03/24/2020

Mass production of IL36RN can be carried out through large-scale fermentation, purification and other processes.

What is the difference between IL36RN protein and IL36α, β, γ? 03/22/2020

This protein is an inhibitor with no biological activity of its own; Recombinant IL36α, β and γ are agonists with different biological effects.

Can recombinant IL36RN be used in clinical trials and therapeutics? 09/24/2019

Can be used in clinical trials and therapy.

Does IL36RN have sustained and stable biological activity? 03/24/2019

IL36RN has sustained and stable biological activity.

Customer Reviews (3)

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Reviews
05/31/2021

    When conducting experiments with IL36RN, clear and consistent results can be obtained, facilitating data analysis and interpretation.

    01/29/2019

      IL36RN has high specific activity and can exert strong biological effect at low concentration.

      01/11/2019

        The stability of the IL36RN product allows it to cope with different experimental conditions and modes of operation.

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