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Official Full Name interleukin-1 receptor-associated kinase 2
Background Interleukin-1 (IL-1) receptor-associated kinase (IRAK) is a serine/threonine-specific kinase that can be coprecipitated in an IL-1-inducible manner with the IL-1 receptor. The mammalian family of IRAK molecules contains four members (IRAK1, IRAK2, IRAK3/I
Synonyms IRAK2; interleukin-1 receptor-associated kinase 2; interleukin-1 receptor-associated kinase-like 2; interleukin-1 receptor associated kinase-2; IRAK-2; MGC150550
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Insect Cell
    • Mammalian Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IRAK2-301417H Recombinant Human IRAK2 protein, GST-tagged E.coli GST
    Human IRAK2-1417H Recombinant Human IRAK2 (Active), GST-tagged Sf9 Insect Cell GST
    Human IRAK2-27503TH Recombinant Human IRAK2 Insect Cell N/A
    Human IRAK2-332H Recombinant Human IRAK2, GST-tagged, Active Sf9 Insect Cell GST
    Human IRAK2-5053H Recombinant Human IRAK2 Protein, GST-tagged Wheat Germ GST
    Human IRAK2-5171HCL Recombinant Human IRAK2 293 Cell Lysate HEK293 N/A
    Human IRAK2-7069H Recombinant Human IRAK2 protein, His-tagged E.coli His
    Mouse Irak2-7070M Recombinant Mouse Irak2 protein, His-tagged E.coli His
    Mouse IRAK2-8293M Recombinant Mouse IRAK2 Protein Mammalian Cell His
    Rat IRAK2-3094R Recombinant Rat IRAK2 Protein Mammalian Cell His
    Rat Irak2-7071R Recombinant Rat Irak2 protein, His-tagged E.coli His
    Chicken IRAK2-2317C Recombinant Chicken IRAK2 Mammalian Cell His

    IRAK2 involved in several pathways and played different roles in them. We selected most pathways IRAK2 participated on our site, such as Apoptosis, Neurotrophin signaling pathway, Tuberculosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with IRAK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Neurotrophin signaling pathway NGF; IRAK4; ZFP110; MAP2K1; IRAK1; TP73; NRAS; MAPK12; NGFRAP1; PIK3CA
    Tuberculosis LBP; BAX; CEBPG; IL6; MAPK9; SPHK1; APAF1; RAB7A; PPP3CB; HLA-DOB

    IRAK2 has several biochemical functions, for example, ATP binding, protein binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IRAK2 itself. We selected most functions IRAK2 had, and list some proteins which have the same functions with IRAK2. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding EIF2AK1; SRC; TAP1; NUBP1; BMPR1BB; YRK; GSK3AB; SYN3; STK39; NEK3
    protein binding GAP43; PTPRZ1; AP2S1; FOXP2; DPYSL2; ADCK5; SUV39H1; MGST1; EIF3D; AIMP2
    protein heterodimerization activity H2AFV; HIST1H2BF; TAS1R3; OSTA; TCF3B; SNX2; HER1; TAP1; TYR; HIF1A
    protein homodimerization activity LGALS6; SRGAP2; CTBP2; SDCBP; TGFB1; NFS1; SNX6; PVRL1; BMP2B; IL6ST
    protein serine/threonine kinase activity SIK3; SMOK3B; RPS6KA3B; MAP2K1; ACVR1; Aatk; CAMK1DB; DCLK3; HIPK1; SRPK2

    IRAK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IRAK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of IRAK2.

    TRAF6; IRAK1; TIRAP; IRAK3; k7_vaccc; ARAF; STT3A; TARDBP; ZC3H12A

    Furi, I; Sipos, F; et al. Association of Self-DNA Mediated TLR9-Related Gene, DNA Methyltransferase, and Cytokeratin Protein Expression Alterations in HT29-Cells to DNA Fragment Length and Methylation Status. SCIENTIFIC WORLD JOURNAL :-(2013).
    Rosenbaek, LL; Assentoft, M; et al. Characterization of a novel phosphorylation site in the sodium-chloride cotransporter, NCC. JOURNAL OF PHYSIOLOGY-LONDON 590:6121-6139(2012).
    Ovsyannikova, I; Haralambieva, I; et al. The role of polymorphisms in Toll-like receptors and their associated intracellular signaling genes in measles vaccine immunity. HUMAN GENETICS 130:547-561(2011).

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