Recombinant Human IRAK2 Protein, GST-tagged

Cat.No. : IRAK2-5053H
Product Overview : Human IRAK2 full-length ORF (BAG35695.1, 1 a.a. - 590 a.a.) recombinant protein with GST-tag at N-terminal.
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Description : IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 91.7 kDa
AA Sequence : MACYIYQLPSWVLDDLCRNMDALSE WDWMEFASYVITDLTQLRKIKSMER VQGVSITRELLWWWGMRQATVQQLV DLLCRLELYRAAQIILNWKPAPEIR CPIPAFPDSVKPEKPLAASVRKAED EQEEGQPVRMATFPGPGSSPARAHQ PAFLQPPEEDAPHSLRSDLPTSSDS KDFSTSIPKQEKLLSLAGDSLFWSE ADVVQATDDFNQNRKISQGTFADVY RGHRHGKPFVFKKLRETACSSPGSI ERFFQAELQICLRCCHPNVLPVLGF CAARQFHSFIYPYMANGSLQDRLQG QGGSDPLPWPQRVSICSGLLCAVEY LHGLEIIHSNVKSSNVLLDQNLTPK LAHPMAHLCPVNKRSKYTMMKTHLL RTSAAYLPEDFIRVGQVTKRVDIFS CGIVLAEVLTGIPAMDNNRSPVYLK DLLLSEIPSSTASLCSRKTGVENVM AKEICQKYLEKGAGRLPEDCAEALA TAACLCLRRRNTSLQEVCGSVAAVE ERLRGRETLLPWSGLSEGTGSSSNT PEETDDVDNSSLDASSSMSVAPWAG AATPLLPTENGEGRLRVIVGREADS SSEACVGLEPPQDVT
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : IRAK2 interleukin-1 receptor-associated kinase 2 [ Homo sapiens ]
Official Symbol : IRAK2
Synonyms : IRAK2; interleukin-1 receptor-associated kinase 2; interleukin-1 receptor-associated kinase-like 2; interleukin-1 receptor associated kinase-2; IRAK-2; MGC150550;
Gene ID : 3656
mRNA Refseq : NM_001570
Protein Refseq : NP_001561
MIM : 603304
UniProt ID : O43187

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any clinical trials targeting IRAK2? 03/07/2022

Yes, there are ongoing clinical trials exploring IRAK2 inhibitors as potential treatments for autoimmune diseases and other conditions.

Is there a diagnostic test for IRAK2-related conditions? 08/28/2021

Currently, there are no widely available diagnostic tests specifically for IRAK2-related conditions. Diagnosis often relies on clinical symptoms and other tests.

How is IRAK2 involved in inflammatory responses? 10/07/2016

IRAK2 is a key player in the inflammatory signaling pathway, which can lead to the production of pro-inflammatory cytokines.

Are there any cancer treatments targeting IRAK2? 07/10/2016

How can gene mutations in IRAK2 affect human health? 04/26/2016

Gene mutations in IRAK2 can disrupt the normal immune response, leading to susceptibility to infections and autoimmune diseases.

Customer Reviews (3)

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Reviews
11/23/2021

    Trusting in its consistent results, I am able to embark on my research with assurance and optimism.

    08/22/2018

      Its unwavering stability and functionality have significantly contributed to the success and validity of my experimental outcomes.

      10/22/2016

        I am profoundly impressed by the technical support rendered by the manufacturer.

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