Recombinant Human IRAK2, GST-tagged, Active
Cat.No. : | IRAK2-332H |
Product Overview : | Recombinant full-length human IRAK2 was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW = 103 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | IRAK2-332H |
Description : | Interleukin-1 receptor-associated kinase 2 (IRAK2) is important downstream signaling components of Toll-like receptors (TLRs). IRAKs were first described as signal transducers for IL-1 and later have been implicated in signal transduction of other members of the Toll/IL-1 receptor family. The interleukin-1 receptor (IL-1R) signaling pathway leads to NFκB activation in mammals. To date, four mammalian IRAKs have been identified (IRAK-1, IRAK-2, IRAK-4, and IRAK-M). It is believed that IRAK-2 could be an additional therapeutic target for inhibiting IL-1-induced inflammation. |
Source : | Sf9 insect cells using baculovirus. |
Sequence : | Full-length. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | IRAK2 interleukin-1 receptor-associated kinase 2 [ Homo sapiens ] |
Synonyms : | IRAK2; interleukin-1 receptor-associated kinase 2; IRAK-2; MGC150550;interleukin-1 receptor associated kinase-2; Interleukin-1 receptor-associated kinase-like 2 |
Gene ID : | 3656 |
mRNA Refseq : | NM_001570 |
Protein Refseq : | NP_001561 |
MIM : | 603304 |
UniProt ID : | O43187 |
Chromosome Location : | 3p25.3 |
Pathway : | Apoptosis; Neurotrophin signaling pathway |
Function : | ATP binding; NF-kappaB-inducing kinase activity; protein heterodimerization activity; protein homodimerization activity; protein kinase activity |
Products Types
◆ Recombinant Protein | ||
IRAK2-2750R | Recombinant Rat IRAK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
IRAK2-5053H | Recombinant Human IRAK2 Protein, GST-tagged | +Inquiry |
IRAK2-4596M | Recombinant Mouse IRAK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
IRAK2-301417H | Recombinant Human IRAK2 protein, GST-tagged | +Inquiry |
IRAK2-2317C | Recombinant Chicken IRAK2 | +Inquiry |
◆ Lysates | ||
IRAK2-5171HCL | Recombinant Human IRAK2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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