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KAT2B

  • Official Full Name

    K(lysine) acetyltransferase 2B

  • Overview

    p300/CBP-associated factor (PCAF), also known as lysine acetyl-transferase 2B (KAT2B), is a transcriptional adaptor protein and histone acetyl-transferase (HAT) that functions as the catalytic subunit of the PCAF transcriptional co-activator complex (1).
  • Synonyms

    KAT2B; K(lysine) acetyltransferase 2B; p300/CBP associated factor , PCAF; histone acetyltransferase KAT2B; GCN5; GCN5L; P/CAF; histone acetylase PCAF; CREBBP-associated factor; p300/CBP-associated factor; lysine acetyltransferase 2B; histone acetyltransfe;

  • Recombinant Proteins
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Sf21 Insect Cell
  • Sf9 Insect Cell
  • Wheat Germ
  • DDK
  • GST
  • His
  • Myc
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KAT2B-1081H Active Recombinant Human K (lysine) Acetyltransferase 2B Sf9 Insect Cell N/A
Human KAT2B-1654H Recombinant Human K (lysine) Acetyltransferase 2B E.coli N/A
Human KAT2B-123H Recombinant Human KAT2B Protein, His-tagged E.coli His 715-831
Human KAT2B-163H Recombinant Human KAT2B, GST-tagged E.coli GST
Human KAT2B-1481H Recombinant Human K(lysine) Acetyltransferase 2B, GST-tagged E.coli GST
Human KAT2B-125H Recombinant Human KAT2B protein, DDK-tagged Insect Cell DDK
Human KAT2B-124H Recombinant Human KAT2B protein, GST-tagged Wheat Germ GST 1 a.a. - 832 a.a.
Human KAT2B-6953H Recombinant Human KAT2B , GST-tagged Sf9 Insect Cell GST 431 aa-end; contains the catalytic domain
Human KAT2B-8483H Recombinant Human KAT2B, His-tagged Sf21 Insect Cell His
Human KAT2B-122H Recombinant Human KAT2B Protein, GST-tagged E.coli GST 715-831
Human KAT2B-126H Recombinant Human KAT2B protein, MYC/DDK-tagged HEK293 Myc/DDK
Human KAT2B-152H Recombinant Human KAT2B Protein, His-tagged Insect Cell His
Human KAT2B-4195H Recombinant Human KAT2B Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human KAT2B-2353H Recombinant Human KAT2B Protein, His-tagged E.coli N-His Ala643-Lys832
Human KAT2B-8485H Recombinant Human KAT2B Protein, His-tagged HEK293 His
Human KAT2B-697HF Recombinant Full Length Human KAT2B Protein, GST-tagged In Vitro Cell Free System GST 832 amino acids
Mouse Kat2b-455M Active Recombinant Mouse Kat2b, His-tagged Sf21 Insect Cell His
Mouse Kat2b-177M Recombinant Mouse K(lysine) Acetyltransferase 2B, His-tagged Sf21 Insect Cell His
Mouse Kat2b-3644M Recombinant Mouse Kat2b Protein, Myc/DDK-tagged HEK293T Myc/DDK
Zebrafish KAT2B-4103Z Recombinant Zebrafish KAT2B Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KAT2B Related Research Area

KAT2B involved in several pathways and played different roles in them. We selected most pathways KAT2B participated on our site, such as Notch signaling pathway, Thyroid hormone signaling pathway, HTLV-I infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with KAT2B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Notch signaling pathwayHER6;DLB;MYCBP;DLL1;MFAP2;APH1C;RBPJL;NOTCH4;DNER
Thyroid hormone signaling pathwayDIO2;PLCD4;AKT2;PIK3CA;PRKCA;PLN;MAPK3;SLC2A1;DIO1
HTLV-I infectionPIK3CG;PDGFA;RANBP1;IL6;PPP3CC;HLA-DPB1;IL1R2;WNT2B;TP53INP1
Viral carcinogenesisBAK1;NFKB2;PSMC1;TRP53;YWHAB;HIST1H4H;UBE3A;HRAS;NRAS

KAT2B has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding, acetyltransferase activity, chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KAT2B itself. We selected most functions KAT2B had, and list some proteins which have the same functions with KAT2B. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II regulatory region sequence-specific DNA bindingSTAT4;SUV39H1;GATA3;H2AFY;EAF2;SP1;ZNF584;SOX13;CGGBP1
acetyltransferase activityAANAT1;KAT6B;MBOAT1;CML5;AANAT2;EP300;KAT5;MBOAT4;HHAT
chromatin bindingGLI2;MEN1;UBTF;KLHDC3;MSGN1;PELP1;CRX;BAHCC1;C19orf40
cyclin-dependent protein serine/threonine kinase inhibitor activityCDKN2C;CDKN2D;CDKN1D;CDKN1BB;Casp3;CDKN1BA;CDKN2B;KAT2B;HEXIM2
histone acetyltransferase activityNCOA3;MGEA5;ATF2;NCOA1;MED24;NCOA2;TAF1;KAT2A;GTF3C4
histone acetyltransferase bindingTP53;CEBPB;SP1;PCNA;EID1;TRIM68;TRIP4;EPAS1;PAX6
histone deacetylase bindingRAD9A;RBBP4;NCOR2;DHX36;RUNX2;MAGEA1;YY1;KAT2A;ZFP932
lysine N-acetyltransferase activity, acting on acetyl phosphate as donorEP300;ESCO2;RHBDL1;NAT8;NAT8B;KAT2B;CEACAM21
protein bindingTULP1;BICD1;CREB3L3;CTC1;UQCC2;NEDD4;TFR2;STON2;STYX
protein complex bindingCDK2;CCNE1;RAN;DRD1A;RANBP2;CFLAR;ATP6V1B1;CYFIP1;SLC27A5
protein kinase bindingTRAP1;TEX14;GPRC5B;DPYSL2;CNPPD1;PRKAB1;KAT2B;PRKCZ;TP53
transcription coactivator activityPDLIM1;ARL2BP;MED1;PIAS1;JUP;CDK7;MED31;GABPA;SETD3
transcription cofactor activityZFP865;NMI;ZFP710;ELK4;LDB2;ZMYND11;CALCOCO1;NFKBIZ;MED14
transcription factor bindingHOXA7;SMARCA4;PITX2;PPP1R13L;NFATC4;MAFB;CSNK2B;PIANP;NAB2

KAT2B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KAT2B here. Most of them are supplied by our site. Hope this information will be useful for your research of KAT2B.

BUB1B; E7; p03255-2

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