LGALS1

  • Official Full Name

    lectin, galactose binding, soluble 1

  • Overview

    Galectin-1 is aprotein that in humans is encoded by the LGALS1 gene. The galectins are afamily of beta-galactoside-binding proteins implicated in modulatingcell-cell and cell-matrix interactions. LGALS1 may act as an autocrinenegative growth factor that regulates cell proliferation.
  • Synonyms

    Lgals1; lectin,galactose binding, soluble 1; L14; Gal-1; Galbp; L-14.5; Lect14; AA410090; galectin-1; galaptin; 14 kDa lectin; S-Lac lectin 1; lactose-binding lectin1; beta-galactoside binding protein; lectin galactoside-binding soluble 1; beta-galactoside-binding lectin L-14-I; GAL1; GBP;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bovine
  • Cattle
  • Chicken
  • Human
  • Mouse
  • Pig
  • Rabbit
  • Rat
  • Rhesus Macaque
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • C
  • His
  • Flag
  • GST
  • His (Fc)
  • Avi
  • Myc
  • His(N
  • ter)
  • His|SUMO
  • SUMO
  • MYC
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LGALS1-6976H Active Recombinant Human Lectin, Galactoside-Binding, Soluble, 1 E.coli His 134 aa
Human LGALS1-669H Recombinant Human LGALS1 protein E.coli N/A 134
Human LGALS1-717H Active Recombinant Human LGALS1 protein E.coli N/A Met1-Asp135
Human LGALS1-261H Recombinant Human LGALS1 Mammalian Cell His
Human LGALS1-730H Recombinant Human LGALS1 Protein, His-tagged E.coli His
Human LGALS1-13121H Recombinant Human LGALS1, GST-tagged E.coli GST 1-135a.a.
Human LGALS1-4770HCL Recombinant Human LGALS1 293 Cell Lysate HEK293 N/A
Human LGALS1-1289H-B Recombinant Human LGALS1 Protein Pre-coupled Magnetic Beads HEK293
Human LGALS1-227H Recombinant Active Human LGALS1 Protein, His-tagged(N-ter) E.coli His(N-ter)
Human LGALS1-1766H Recombinant Human LGALS1 protein, His-tagged E.coli His Met1~Asp135
Human LGALS1-3164H Recombinant Human LGALS1 protein, His&Myc-tagged E.coli His&Myc 2-135aa
Human LGALS1-3142H Recombinant Human LGALS1 Protein (Met1-Asp135), C-His tagged E.coli C-His Met1-Asp135
Human LGALS1-1706HFL Recombinant Full Length Human LGALS1 Protein, C-Flag-tagged Mammalian cells Flag
Human LGALS1-3163H Recombinant Human LGALS1 protein, His-SUMO-tagged E.coli His-SUMO 2-135aa
Human LGALS1-2154H Recombinant Human LGALS1 protein E.coli N/A Met 1 - Asp 135
Human LGALS1-3143H Recombinant Human LGALS1 Protein (Ala2-Asp135), C-His tagged E.coli C-His Ala2-Asp135
Human LGALS1-204H Active Recombinant Human LGALS1 Protein E.coli
Human LGALS1-189H Active Recombinant Human LGALS1 Protein (Ala2-Asp135), N-His tagged, Animal-free, Carrier-free E.coli N-His Ala2-Asp135
Human LGALS1-1289H Recombinant Human LGALS1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Lgals1-4007M Active Recombinant Mouse Lgals1 protein(Met1-Glu135) E. coli N/A Met1-Glu135
Mouse LGALS1-7210M Recombinant Mouse Lectin, Galactoside-Binding, Soluble, 1, His-tagged E.coli His 1-135aa
Mouse Lgals1-1310M Recombinant Mouse Lgals1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse Lgals1-7256M Recombinant Mouse Lgals1 Protein, His-tagged E.coli His 1-135
Rat Lgals1-8747R Recombinant Rat Lgals1, None tagged E.coli N/A
Rat LGALS1-3385R Recombinant Rat LGALS1 Protein Mammalian Cell His
Rat Lgals1-458R Recombinant Rat Lgals1 Protein, His-tagged E.coli His Met1~Glu135
Rat LGALS1-3041R-B Recombinant Rat LGALS1 Protein Pre-coupled Magnetic Beads HEK293
Rat LGALS1-3041R Recombinant Rat LGALS1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rabbit LGALS1-456R Recombinant Rabbit LGALS1 Protein, His-tagged E.coli His Ala2~Glu135
Bovine LGALS1-1989B Recombinant Bovine LGALS1 Protein (2-135 aa), His-SUMO-tagged E.coli His/SUMO 2-135 aa
Cattle LGALS1-454C Recombinant Cattle LGALS1 Protein, His-tagged E.coli His Met1~Glu135
Rhesus Macaque LGALS1-2500R Recombinant Rhesus monkey LGALS1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque LGALS1-2321R Recombinant Rhesus Macaque LGALS1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque LGALS1-2321R-B Recombinant Rhesus Macaque LGALS1 Protein Pre-coupled Magnetic Beads HEK293
Pig LGALS1-457P Recombinant Pig LGALS1 Protein, His-tagged E.coli His Ala2~Glu135
Chicken LGALS1-7044C Recombinant Chicken LGALS1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • LGALS1 Related Articles

LGALS1 involved in several pathways and played different roles in them. We selected most pathways LGALS1 participated on our site, such as Validated targets of C-MYC transcriptional repression, which may be useful for your reference. Also, other proteins which involved in the same pathway with LGALS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Validated targets of C-MYC transcriptional repressionSFXN3;ZFP36L1;CLU;LGALS1;MXD4;DNTT;S100A7;TMEM126A;TMEFF2

LGALS1 has several biochemical functions, for example, glycoprotein binding, lactose binding, laminin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LGALS1 itself. We selected most functions LGALS1 had, and list some proteins which have the same functions with LGALS1. You can find most of the proteins on our site.

Function Related Protein
glycoprotein bindingSERPINA1D;RASA1;CSNK1D;BMPR1B;B2M;SERPINA1;FBXO27;DNAJC5;DNAJA2
lactose bindingLGALS12;LGALS1
laminin bindingITGA9;THBS1;NID1;ADAM9;LGALS1;TINAGL1;ACHE;ITGB1;LYPD3
poly(A) RNA bindingPKM2;HIST1H4B;ANXA11;SF3A1;RPL21;MRTO4;PRDX1;PUS1;TRAP1
protein bindingNR2C1;MRPL27;DTNBP1;FAM123A;CCDC106;RPF1;FRMD5;RHOG;IMP4
protein homodimerization activityXPA;HEXB;TFRC;S100A13;SYT14;HIF1AN;Defa-rs7;TYRP1;AMICA1
signal transducer activityGNAL;CELSR1;DRD4B;PLCD4;CTNNB2;TAS2R138;TAS1R2.1;VMN1R44;GRM6A

LGALS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LGALS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LGALS1.

ALCAM; KDR; PTPRC; CD6; VCAM1; FLT1; YWHAZ; Trim69; SUSD2; TFAP2A; CDC42

Romaniuk, MA; Croci, DO; et al. Binding of galectin-1 to alpha(IIb)beta(3) integrin triggers "outside-in" signals, stimulates platelet activation, and controls primary hemostasis. FASEB JOURNAL 26:2788-2798(2012).
Perotti, C; Wiedl, T; et al. Characterization of mammary epithelial cell line HC11 using the NIA 15k gene array reveals potential regulators of the undifferentiated and differentiated phenotypes. DIFFERENTIATION 78:269-282(2009).
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