Active Recombinant Human LGALS1 Protein (Ala2-Asp135), N-His tagged, Animal-free, Carrier-free

• Cat.No.: LGALS1-189H
• Product Overview: Recombinant Human LGALS1 Protein (Ala2-Asp135) with N-His tag was expressed in E. coli and Animal-free as well as Carrier-free.

Specification

• Description: Galectin-1 (Gal-1) is a lectin family member. Galectin-1 contains one carbohydrate recognition domain (CRD), responsible for β-galactoside binding, and is biologically active as homodimers. Several binding partners for galectin-1 have been identified, including CD45, CD43, CD69, pre-BCR, and vascular endothelial Growth Factors R2. Galectin-1 is constitutively presented in the immune system and other tissues, contributing to cell growth, proliferation, and apoptosis. The galectin-1 plays a central role in regulating acute and chronic inflammatory responses.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Lyophilized
• Bio-activity: Measured by its ability to agglutinate human red blood cells. The ED50 for this effect is < 2 μg/mL.
• Molecular Mass: The protein has a calculated MW of 15.5 kDa.
  The protein migrates as 15 kDa under reducing condition (SDS-PAGE analysis).
• Protein Length: Ala2-Asp135
• Endotoxin: < 0.1 EU/μg of the protein by the LAL method.
• Purity: >98% as determined by SDS-PAGE analysis.
• Storage: This product is stable after storage at:
  -20 centigrade for 12 months in lyophilized state from date of receipt.
  -20 or -80 centigrade for 1 month under sterile conditions after reconstitution.
  Avoid repeated freeze/thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Reconstitution: It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
• Shipping: The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage.

Gene Information

• Gene Name: LGALS1 lectin, galactoside-binding, soluble, 1 [ Homo sapiens (human) ]
• Official Symbol: LGALS1
• Synonyms: LGALS1; lectin, galactoside-binding, soluble, 1; galectin-1; galectin 1; GBP; HBL; HPL; gal-1; HLBP14; galaptin; 14 kDa lectin; S-Lac lectin 1; lactose-binding lectin 1; 14 kDa laminin-binding protein; putative MAPK-activating protein PM12; beta-galactoside-binding lectin L-14-I; beta-galactoside-binding protein 14kDa; GAL1; DKFZp686E23103
• Gene ID: 3956
• mRNA Refseq: NM_002305
• Protein Refseq: NP_002296
• MIM: 150570
• UniProt ID: P09382