LY96

  • Official Full Name

    lymphocyte antigen 96

  • Overview

    This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2010]
  • Synonyms

    LY96; lymphocyte antigen 96; MD2; MD-2; ly-96; ESOP-1; protein MD-2; myeloid differentiation protein-2;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cell & Tissue Lysates
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rhesus Macaque
  • Baculovirus-Insect cells
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • Insect Cell
  • Mamanlian cells
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • Flag
  • Myc
  • GST
  • His (Fc)
  • Avi
  • SUMO
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LY96-445H Active Recombinant Human LY96 protein, His-tagged E.coli His
Human LY96-154H Recombinant Human LY96, GST-tagged Wheat Germ GST
Human LY96-1548H Recombinant Human Lymphocyte Antigen 96, His-tagged E.coli His
Human LY96-327H Recombinant Human LY96 protein, MYC/DDK-tagged HEK293 Myc/DDK
Human LY96-4987HFL Recombinant Full Length Human LY96 protein, Flag-tagged Mamanlian cells Flag
Human LY96-1331H-B Recombinant Human LY96 Protein Pre-coupled Magnetic Beads HEK293
Human LY96-2240H Recombinant Human LY96 protein, His-tagged Insect Cell His
Human LY96-1331H Recombinant Human LY96 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human LY96-1707HFL Recombinant Full Length Human LY96 Protein, C-Flag-tagged Mammalian cells Flag
Human LY96-3191H Recombinant Human LY96 protein, His-GST & Myc-tagged E.coli His-GST & Myc
Human LY96-0381H Recombinant Human LY96 Protein (Gln19-Asn160), C-His-tagged Baculovirus-Insect cells C-His
Human LY96-3192H Recombinant Human LY96 protein, His-tagged E.coli His
Human LY96-4157H Recombinant Human LY96 Protein E.coli
Human LY96-4158H Recombinant Human LY96 Protein (Met1-Asn160), C-His tagged Mammalian cells C-His
Human LY96-4159H Recombinant Human LY96 Protein (Glu17-Asn160), N-His tagged E.coli N-His
Mouse LY96-105M Recombinant Mouse Ly96, Fc tagged Human Cell His
Mouse LY96-771MCL Recombinant Mouse LY96 cell lysate Human Cell N/A
Mouse Ly96-3193M Recombinant Mouse Ly96 protein, His-SUMO-tagged E.coli His-SUMO
Mouse Ly96-1551M Recombinant Mouse Ly96 protein, His-tagged E.coli His
Mouse Ly96-3875M Recombinant Mouse Ly96 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Ly96-5036M Recombinant Mouse Ly96 protein, Flag-Myc-tagged HEK293 Flag-Myc
Cynomolgus Monkey LY96-668C Recombinant Cynomolgus LY96 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey LY96-414C Recombinant Cynomolgus Monkey LY96 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey LY96-414C-B Recombinant Cynomolgus Monkey LY96 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque LY96-2600R Recombinant Rhesus monkey LY96 Protein, His-tagged Mammalian Cell His
Rhesus Macaque LY96-2420R Recombinant Rhesus Macaque LY96 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque LY96-2420R-B Recombinant Rhesus Macaque LY96 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • LY96 Related Articles
  • LY96 Related Research Area

LY96 involved in several pathways and played different roles in them. We selected most pathways LY96 participated on our site, such as NF-kappa B signaling pathway, Toll-like receptor signaling pathway, Pathogenic Escherichia coli infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with LY96 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
NF-kappa B signaling pathwayDDX58;CCL4;TRAF1;MYD88;GM10591;BCL10;TRAF5;CCL4L1;CXCL2
Toll-like receptor signaling pathwayFOS;MAPK3;NFKBIA;IL8L2;CD40;IFNA5;IFNPHI1;CD14;TICAM2
Pathogenic Escherichia coli infectionARPC5L;TUBA1C;TUBB7P;CDH1;HCLS1;TUBA4A;TUBB;TUBA1A;OCLN
PertussisC5;C4A;IL1A;ITGA5;LY96;MAPK12;CASP7;AMCF-II;MAPK1
ToxoplasmosisMAPK10;STAT3;MAPK13;TLR2;ITGA6;AKT2;TRAF6;CYCS;MAPK12

LY96 has several biochemical functions, for example, coreceptor activity, lipopolysaccharide receptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LY96 itself. We selected most functions LY96 had, and list some proteins which have the same functions with LY96. You can find most of the proteins on our site.

Function Related Protein
coreceptor activityCXCR7B;RAMP2;IGSF1;HFE2;CD86;ACVR2A;TGFBR3;CXCR6;ZP2
lipopolysaccharide receptor activitySCARB1;PTAFR;TLR4;LY96;TLR2
protein bindingERLIN1;CEBPG;SMN1;EMG1;EPS15L1;MARCH10;TXNL4A;CEACAM1;CCDC88A

LY96 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LY96 here. Most of them are supplied by our site. Hope this information will be useful for your research of LY96.

TLR4; eritoran tetrasodium; tlr4_q4g1l2_tv8_prot; HMGB1; Hmgb1; CDKN2C

Pishraft-Sabet, L; Kosinska, AD; et al. Enhancement of HCV polytope DNA vaccine efficacy by fusion to an N-terminal fragment of heat shock protein gp96. ARCHIVES OF VIROLOGY 160:141-152(2015).
Lin, XF; Zhu, H; et al. Near-Infrared Fluorescence Imaging of Non-Hodgkin's Lymphoma CD20 Expression Using Cy7-Conjugated Obinutuzumab. MOLECULAR IMAGING AND BIOLOGY 16:877-887(2014).
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