LY96
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Official Full Name
lymphocyte antigen 96
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Overview
This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2010] -
Synonyms
LY96; lymphocyte antigen 96; MD2; MD-2; ly-96; ESOP-1; protein MD-2; myeloid differentiation protein-2;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Cell & Tissue Lysates
- Cynomolgus Monkey
- Human
- Mouse
- Rhesus Macaque
- Baculovirus-Insect cells
- E. coli
- E.coli
- HEK293
- HEK293T
- Human Cell
- Insect Cell
- Mamanlian cells
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Fc
- Flag
- Myc
- GST
- His
- Avi
- SUMO
- DDK
- N
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
LY96 involved in several pathways and played different roles in them. We selected most pathways LY96 participated on our site, such as NF-kappa B signaling pathway, Toll-like receptor signaling pathway, Pathogenic Escherichia coli infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with LY96 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| NF-kappa B signaling pathway | TNFAIP3;LTB;PLCG2;TRADD;GM10591;DDX58;IKBKG;CD40;BTK |
| Toll-like receptor signaling pathway | PIK3R3;IL6;CXCL8B.3;PIK3R5;AKT3A;MYD88;CCL5;CCL3L1;CCL4 |
| Pathogenic Escherichia coli infection | HCLS1;FYN;TUBA3D;TUBB6;TUBB;TUBA4A;ACTB;YWHAZ;TUBB2A |
| Pertussis | C1S;C4A;CXCL5;IL12B;MAPK9;NOS2;SERPING1;C1RA;NLRP3 |
| Toxoplasmosis | HSPA8;LAMB2;BCL2;Toxoplasma Gondii Profilin Family Protein;HSPA6;LAMA2;RELA;GNAI3;IRAK1 |
LY96 has several biochemical functions, for example, coreceptor activity, lipopolysaccharide receptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LY96 itself. We selected most functions LY96 had, and list some proteins which have the same functions with LY96. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| coreceptor activity | LY96;RAMP3;CD86;ACVR2A;CXCR4;TMIGD2;CD80;CCR8;RGMB |
| lipopolysaccharide receptor activity | SCARB1;PTAFR;LY96;TLR2;TLR4 |
| protein binding | NPLOC4;ZNF227;HDGFRP2;BTK;OBSCN;TMEM190;CD37;AP5Z1;MTA3 |
LY96 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LY96 here. Most of them are supplied by our site. Hope this information will be useful for your research of LY96.
TLR4; eritoran tetrasodium; tlr4_q4g1l2_tv8_prot; HMGB1; Hmgb1; CDKN2C
Research Area
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