MCAM
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Official Full Name
melanoma cell adhesion molecule
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Overview
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration. -
Synonyms
MCAM; melanoma cell adhesion molecule; cell surface glycoprotein MUC18; CD146; Gicerin; MUC18; melanoma adhesion molecule; cell surface glycoprotein P1H12; melanoma-associated antigen A32; melanoma-associated antigen MUC18; S-endo 1 endothelial-associated antigen;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Others
- Chicken
- Cynomolgus
- Homo sapiens (Human)
- Human
- Mouse
- Rat
- E.coli
- E.coli expression system
- HEK293
- HEK293T
- Human Cell
- Human Cells
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Fc
- Flag
- His
- Avi
- T7
- Myc
- DDK
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
MCAM involved in several pathways and played different roles in them. We selected most pathways MCAM participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MCAM were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
MCAM has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by MCAM itself. We selected most functions MCAM had, and list some proteins which have the same functions with MCAM. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
MCAM has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MCAM here. Most of them are supplied by our site. Hope this information will be useful for your research of MCAM.
gd3; ATF7IP; UBE2O; CD9
Research Area
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