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Official Full Name myosin, light chain 6, alkali, smooth muscle and non-muscle
Background Myosin light polypeptide 6 is a protein that in humans is encoded by the MYL6 gene. Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain that is expressed in smooth muscle and non-muscle tissues. Genomic sequences representing several pseudogenes have been described and two transcript variants encoding different isoforms have been identified for this gene
Synonyms MYL6; myosin, light chain 6, alkali, smooth muscle and non-muscle; myosin, light polypeptide 6, alkali, smooth muscle and non muscle; myosin light polypeptide 6; ESMLC; MLC1SM; MLC3NM; myosin light chain A3; 17 kDa myosin light chain; myosin light chain a
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MYL6-3441H Recombinant Human MYL6 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Myl6-4253M Recombinant Mouse Myl6 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human MYL6-6207H Recombinant Human MYL6 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human MYL6-30266TH Recombinant Human MYL6, His-tagged E.coli His
    Human MYL6-30267TH Recombinant Human MYL6 N/A
    Human MYL6-3446H Recombinant Human MYL6 protein, His-tagged E.coli His
    Human MYL6-4023HCL Recombinant Human MYL6 293 Cell Lysate HEK293 N/A
    Human MYL6-4024HCL Recombinant Human MYL6 293 Cell Lysate HEK293 N/A
    Human MYL6-5814H Recombinant Human MYL6 Protein, GST-tagged Wheat Germ GST
    Mouse MYL6-10317M Recombinant Mouse MYL6 Protein Mammalian Cell His
    Rhesus Macaque MYL6-2923R Recombinant Rhesus monkey MYL6 Protein, His-tagged Mammalian Cell His
    Zebrafish MYL6-1485Z Recombinant Zebrafish MYL6 Mammalian Cell His

    myl6 involved in several pathways and played different roles in them. We selected most pathways myl6 participated on our site, such as Vascular smooth muscle contraction, Oxytocin signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with myl6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Vascular smooth muscle contraction PLA2G2D; NPR1; PPP1CA; PRKCG; RHOAA; CACNA1SA; PLA2G12B; PRKACAB; GNAQ; MAPK3
    Oxytocin signaling pathway CAMKK2; PRKAB2; PRKAA1; NRAS; PRKACG; KCNJ14; CACNA2D3; FOS; CALM3; CACNB2

    myl6 has several biochemical functions, for example, actin-dependent ATPase activity, calcium ion binding, motor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by myl6 itself. We selected most functions myl6 had, and list some proteins which have the same functions with myl6. You can find most of the proteins on our site.

    Function Related Protein
    actin-dependent ATPase activity MYH9; MYO7A; MYO1D; MYL6; MYO1C; MYH7; MYO3A; MYH10
    calcium ion binding FREM2; S100A14; ARSA; DSG1; SLC24A5; DSG1C; PRRG1; F9B; PCDH10; CRB2B
    motor activity DNALC4; VMHC; DYNLT3; MYO6A; MYL6; MYH15; KIF3C; KIF18B; MYO1H; DYNC2H1
    protein binding ELMOD3; SWAP70; CCDC25; UBE2D2; FBXO7; TP53INP1; DIRAS3; PHOSPHO2; TTPA; DAO
    structural constituent of muscle MYL6B; MYOM1; TCAP; MYL6; MYBPC2; TPM1; ASPH; JPH1; ACTN3; MYOT

    myl6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with myl6 here. Most of them are supplied by our site. Hope this information will be useful for your research of myl6.

    ESR1; IKBKE; ADAMTS12; VCAM1; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate; PPP2R2B; ESR2

    Yuan, SQ; Stratton, CJ; et al. Spata6 is required for normal assembly of the sperm connecting piece and tight head-tail conjunction. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112:E430-E439(2015).
    Tsai, CJ; Lin, YC; et al. Chemical derivatization combined with capillary LC or MALDI-TOF MS for trace determination of lipoic acid in cosmetics and integrated protein expression profiling in human keratinocytes. TALANTA 130:347-355(2014).

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