NFE2L2

  • Official Full Name

    nuclear factor, erythroid 2-like 2

  • Overview

    This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
  • Synonyms

    NFE2L2; nuclear factor, erythroid 2-like 2; NRF2; nuclear factor erythroid 2-related factor 2; HEBP1; NFE2-related factor 2; NF-E2-related factor 2; nuclear factor erythroid-derived 2-like 2; nuclear factor (erythroid-derived 2)-like 2; nuclear factor, erythroid derived 2, like 2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • His|MBP
  • His|T7
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NFE2L2-30414TH Recombinant Human NFE2L2 Wheat Germ N/A 100 amino acids
Human NFE2L2-8469H Recombinant Human NFE2L2, His-tagged E.coli His
Human NFE2L2-359H Recombinant Human NFE2L2 protein, His/MBP-tagged E.coli His/MBP 331-605 aa
Human NFE2L2-3854HCL Recombinant Human NFE2L2 293 Cell Lysate HEK293 N/A
Human NFE2L2-1917H Recombinant Human NFE2L2 protein, His & GST-tagged E.coli His/GST Ser400~Lys603 (Accession # Q16236)
Human NFE2L2-001H Recombinant Human NFE2L2 Protein, MYC/DDK-tagged HEK293T Myc/DDK
Human NFE2L2-4685H Recombinant Human NFE2L2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human NFE2L2-4426H Recombinant Human NFE2L2 protein, His-tagged E.coli His 1-605aa
Human NFE2L2-1506H-B Recombinant Human NFE2L2 Protein Pre-coupled Magnetic Beads HEK293
Human NFE2L2-154HFL Recombinant Full Length Human NFE2L2 Protein, C-Flag-tagged Mammalian cells Flag
Human NFE2L2-1211H Recombinant Human NFE2L2 protein, GST-tagged E.coli GST 256-605 aa
Human NFE2L2-4688H Recombinant Human NFE2L2 Protein (Met17-Asn605), N-His tagged E.coli N-His Met17-Asn605
Human NFE2L2-48HFL Recombinant Full Length Human NFE2L2 Protein, N-His-tagged E.coli His
Human NFE2L2-1506H Recombinant Human NFE2L2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse NFE2L2-10615M Recombinant Mouse NFE2L2 Protein Mammalian Cell His
Mouse NFE2L2-125M Recombinant Mouse NFE2L2 protein, His-tagged E.coli His Ala375-Asn597
Mouse NFE2L2-6033M-B Recombinant Mouse NFE2L2 Protein Pre-coupled Magnetic Beads HEK293
Mouse Nfe2l2-4392M Recombinant Mouse Nfe2l2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse NFE2L2-6033M Recombinant Mouse NFE2L2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat NFE2L2-3972R Recombinant Rat NFE2L2 Protein Mammalian Cell His
Rat NFE2L2-3631R Recombinant Rat NFE2L2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat NFE2L2-3631R-B Recombinant Rat NFE2L2 Protein Pre-coupled Magnetic Beads HEK293
Rat Nfe2l2-1918R Recombinant Rat Nfe2l2 protein, His & T7-tagged E.coli His/T7 Ala382~Asn604 (Accession # O54968)
Rhesus Macaque NFE2L2-3013R Recombinant Rhesus monkey NFE2L2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque NFE2L2-2832R Recombinant Rhesus Macaque NFE2L2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque NFE2L2-2832R-B Recombinant Rhesus Macaque NFE2L2 Protein Pre-coupled Magnetic Beads HEK293
Chicken NFE2L2-6674C Recombinant Chicken NFE2L2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • NFE2L2 Related Research Area

NFE2L2 involved in several pathways and played different roles in them. We selected most pathways NFE2L2 participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with NFE2L2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Protein processing in endoplasmic reticulumSEC24D;PPP1R15A;BCAP31;VCP;HSPA8;EIF2AK2;MAPK10;TRAF2;DNAJC5GA

NFE2L2 has several biochemical functions, for example, DNA binding, RNA polymerase II activating transcription factor binding, RNA polymerase II distal enhancer sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NFE2L2 itself. We selected most functions NFE2L2 had, and list some proteins which have the same functions with NFE2L2. You can find most of the proteins on our site.

Function Related Protein
DNA bindingPOLR3C;SMARCB1A;IRX3B;ZFAND6;SETDB2;LIG1;NCOR2;ZFP143;ZBTB42
RNA polymerase II activating transcription factor bindingZFPM1;EOMES;NCOR1;TP53BP1;NFE2L2;LMO2;CREB1;HEY2;HNF4A
RNA polymerase II distal enhancer sequence-specific DNA bindingNFE2L2;FLI1;NR5A1;NFKB1;BACH1;CDX2;MSC;ATF2;RUVBL2
protein bindingFAM154A;CPSF6;DYNC2LI1;POLR2A;MTAP1B;GTF2A2;P2RY6;TXNDC9;LIG3
protein domain specific bindingCHMP1A;CALM2;EHD2;CRB3;MED12;YWHABB;SCAF1;YWHAB;ARFIP2A
transcription factor activity, sequence-specific DNA bindingJUN;RUNX2A;ZNF493;POU6F2;NFIL3;POU2F1A;ZNF518A;CBL;HSF2
transcription regulatory region DNA bindingGFI1;HNRNPL;TA;XBP1;SALL2;IKZF1;TRP63;ZBTB14;SALL3
transcription regulatory region sequence-specific DNA bindingPOU2F1;PITX2;NR5A1;MEF2CA;FOXN1;NFE2L2B;DDIT3;NFE2L1A;EPAS1B
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific bindingFOXH1;RELA;FUBP1;SIX3;HCFC1;BACH1;SPI1;POU4F1;PROP1

NFE2L2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NFE2L2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NFE2L2.

KEAP1; MAFG

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Reviews
03/01/2021

    The NFE2L2 proteins purchased from your company is suitable for ELISA.

    12/04/2020

      The technician modified my experimental protocol so that my experiment went smoothly.

      11/21/2020

        Very good after-sales service to get my experiments going!

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