NPPA

  • Official Full Name

    natriuretic peptide A

  • Overview

    Atrial natriuretic peptide (ANP), atrial natriuretic factor (ANF), atrial natriuretic hormone (ANH), or atriopeptin, is a powerful vasodilator, and a protein (polypeptide) hormone secreted by heart muscle cells. It is involved in the homeostatic control of body water, sodium, potassium and fat (adipose tissue). It is released by muscle cells in the upper chambers (atria) of the heart (atrial myocytes), in response to high blood pressure. ANP acts to reduce the water, sodium and adipose loads on the circulatory system, thereby reducing blood pressure.

  • Synonyms

    Nppa;natriuretic peptide precursor A;ANF;ANP;Pnd;RATANF;natriuretic peptides A;prepronatriodilatin;atrial natriuretic factor;atrial natriuretic peptide;natriuretic peptide precursor type A;Natriuretic peptide precursor A (pronatriodilatin, also Anf, Pnd);Auriculin-B;Auriculin-A;Atriopeptin-1;Atriopeptin I;Atriopeptin-2;Atriopeptin II;Atriopeptin-3;Atriopeptin IIIy

Recombinant Proteins

  • Human
  • Mouse
  • Cattle
  • Rat
  • Zebrafish
  • E.coli
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • Yeast
  • In Vitro Cell Free System
  • GST
  • His
  • T7
  • Non
  • KSI
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
NPPA-1347H Recombinant Human NPPA, GST-tagged E.coli Human GST 1-153aa
NPPA-3689H Recombinant Human NPPA protein, His-tagged E.coli Human His 26-153 aa
NPPA-10830M Recombinant Mouse NPPA Protein Mammalian Cells Mouse His
NPPA-259C Recombinant Cattle NPPA Protein, His-tagged E.coli Cattle His Asn25~Arg152
Nppa-260M Recombinant Mouse Nppa Protein, His/GST-tagged E.coli Mouse GST&His Asn25~Arg152
Nppa-261R Recombinant Rat Nppa Protein, His/GST-tagged E.coli Rat GST&His Asn25~Arg152
Nppa-263R Recombinant Rat Nppa Protein, His-tagged E.coli Rat His Asn25~Arg122
NPPA-2689H Recombinant Human NPPA protein, His & GST-tagged E.coli Human GST&His Ala25~Arg123
Nppa-2690M Recombinant Mouse Nppa protein, His & T7-tagged E.coli Mouse His&T7 Asn25~Arg122
NPPA-27326TH Recombinant Human NPPA Wheat Germ Human Non 153 amino acids
NPPA-35H Recombinant Human NPPA protein, His-tagged E.coli Human His
NPPA-9835Z Recombinant Zebrafish NPPA Mammalian Cells Zebrafish His
NPPA-3735HCL Recombinant Human NPPA 293 Cell Lysate HEK293 Human Non
NPPA-1252H Recombinant Human NPPA protein, His-tagged Yeast Human His 78-115AA
NPPA-1850H Recombinant Human NPPA Protein, His&GST-tagged E.coli Human GST&His Lys41-Tyr151
Nppa-2212M Recombinant Mouse Nppa protein(123-150aa), His-KSI-tagged E.coli Mouse His&KSI 123-150aa
NPPA-347HF Recombinant Full Length Human NPPA Protein In Vitro Cell Free System Human Full L. 153 amino acids
NPPA-385H Recombinant Human NPPA Protein, His-tagged E.coli Human His Ser124-Tyr151
Nppa-386R Recombinant Rat Nppa Protein, His&GST-tagged E.coli Rat GST&His Asn25-Arg122
Nppa-387R Recombinant Rat Nppa Protein, His-tagged E.coli Rat His Asn25-Arg122
NPPA-4730H Recombinant Human NPPA Protein (Ala25-Arg123), N-GST tagged E.coli Human GST Ala25-Arg123
NPPA-6041H Recombinant Human NPPA Protein, GST-tagged Wheat Germ Human GST
NPPA-6169M Recombinant Mouse NPPA Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
NPPA-6169M-B Recombinant Mouse NPPA Protein Pre-coupled Magnetic Beads HEK293 Mouse
NPPA-6641HF Recombinant Full Length Human NPPA Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 153 amino acids
NPPA-79H Human Atrial Natriuretic Factor Reference standard Human Non

    Involved Pathway

    NPPA involved in several pathways and played different roles in them. We selected most pathways NPPA participated on our site, such as HIF- signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NPPA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    HIF- signaling pathway TF,HKDC1,BCL2,RELA,EP300,EPO,GAPDH,MAP2K2,NOS3,MKNK2

    Protein Function

    NPPA has several biochemical functions, for example, neuropeptide hormone activity,neuropeptide receptor binding,peptide hormone receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NPPA itself. We selected most functions NPPA had, and list some proteins which have the same functions with NPPA. You can find most of the proteins on our site.

    Function Related Protein
    neuropeptide hormone activity PENK,CALCB,GRP,NPFFL,UCN,PNOC,AGRP,NPY,NTS,QRFP
    peptide hormone receptor binding LEP,PTHLHA,PTHLH,FYN,PTH,ADCYAP1,PTPN11,RUNDC3A,JAK2,NPPC
    protein binding PFKFB2,AOC3,PCDH18,RBM10,NHLRC2,CA,SNRPE,KIF4A,PIM3,CHMP4B
    receptor binding LAMA1,F2,CD86,DECR2,FGG,PTK2,F2R,CNTFR,CCL13,FGF12A

    Interacting Protein

    NPPA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NPPA here. Most of them are supplied by our site. Hope this information will be useful for your research of NPPA.

    MAGEA12;UBQLN1;UBQLN4

    Resources

    Research Area

    References

    • Pereira, NL; Tosakulwong, N; et al. Circulating Atrial Natriuretic Peptide Genetic Association Study Identifies a Novel Gene Cluster Associated With Stroke in Whites. CIRCULATION-CARDIOVASCULAR GENETICS 8:141-U292(2015).
    • Ovchinnikov, DA; Hidalgo, A; et al. Isolation of Contractile Cardiomyocytes from Human Pluripotent Stem-Cell-Derived Cardiomyogenic Cultures Using a Human NCX1-EGFP Reporter. STEM CELLS AND DEVELOPMENT 24:11-20(2015).

    Reviews

    Write a review

    Q&As

    Ask a question

    Ask a Question for All NPPA Products

    Required fields are marked with *

    My Review for All NPPA Products

    Required fields are marked with *