Recombinant Full Length Human NPPA Protein, Flag tagged

• Cat.No.: NPPA-22HFL
• Product Overview: Recombinant Full Length Human NPPA Protein with Flag tag was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Flag
• Protein Length: 1-151 aa
• Description: The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. This gene is located adjacent to another member of the natriuretic family of peptides on chromosome 1.
• Form: 25 mM Tris-HCl, 100 mM glycine, and 10% glycerol, 250 mM NaCl, pH 7.3
• Molecular Mass: 17.39 kDa
• Endotoxin: < 0.10 EU/μg of the protein by the LAL method.
• Purity: 88.3% by SDS-PAGE
• Notes: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Stable for at least 1 year from receipt of products under proper storage and handling conditions.
• Concentration: 0.12 mg/mL by Bradford

Gene Information

• Gene Name: NPPA natriuretic peptide A [ Homo sapiens (human) ]
• Official Symbol: NPPA
• Synonyms: NPPA; natriuretic peptide A; ANP, natriuretic peptide precursor A, PND; natriuretic peptides A; atriopeptin; cardionatrin; prepronatriodilatin; natriuretic peptide precursor A; ANF; ANP; PND; ATFB6; CDD-ANF
• Gene ID: 4878
• mRNA Refseq: NM_006172
• Protein Refseq: NP_006163
• MIM: 108780
• UniProt ID: P01160