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Official Full Name programmed cell death 4 (neoplastic transformation inhibitor)
Background This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
Synonyms PDCD4; programmed cell death 4 (neoplastic transformation inhibitor); H731; programmed cell death protein 4; protein 197/15a; nuclear antigen H731; neoplastic transformation inhibitor protein;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • E.coli
    • Mammalian Cell
    • Rabbit
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CPBT-56409RH Rabbit Anti-Human PDCD4 Polyclonal Antibody Rabbit N/A
    Human CPBT-56410RH Rabbit Anti-Human PDCD4 Polyclonal Antibody Rabbit N/A
    Human PDCD4-1320HCL Recombinant Human PDCD4 cell lysate N/A
    Human PDCD4-1593H Recombinant Human PDCD4, GST-tagged E.coli GST
    Human PDCD4-175H Recombinant Human PDCD4 E.coli N/A
    Human PDCD4-30797TH Recombinant Human PDCD4 Wheat Germ N/A
    Human PDCD4-484H Recombinant Human PDCD4 Protein, His-tagged E.coli His
    Mouse PDCD4-12535M Recombinant Mouse PDCD4 Protein Mammalian Cell His
    Rhesus Macaque PDCD4-3341R Recombinant Rhesus monkey PDCD4 Protein, His-tagged Mammalian Cell His
    Chicken PDCD4-5877C Recombinant Chicken PDCD4 Mammalian Cell His

    pdcd4 involved in several pathways and played different roles in them. We selected most pathways pdcd4 participated on our site, such as Proteoglycans in cancer, MicroRNAs in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with pdcd4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Proteoglycans in cancer WNT3; TWIST2; PLCG1; COL21A1; CAMK2B; PXN; ITGB3; TRP53; CTTN; CAMK2D
    MicroRNAs in cancer FOXP1; PIM1; TP53; BRCA1; HOXD10; FZD3; SOX4; NRAS; RPS6KA5; EFNA3

    pdcd4 has several biochemical functions, for example, RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by pdcd4 itself. We selected most functions pdcd4 had, and list some proteins which have the same functions with pdcd4. You can find most of the proteins on our site.

    Function Related Protein
    protein binding COMMD7; LARP4; AHSA1; PRL; FCHSD2; RNF146; RALGDS; E2F5; RNF135; CECR2

    pdcd4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with pdcd4 here. Most of them are supplied by our site. Hope this information will be useful for your research of pdcd4.

    EIF4A2; EIF4A1; RELA; EIF4A3; RPS13

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