|Official Full Name||programmed cell death 4 (neoplastic transformation inhibitor)|
|Background||This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]|
|Synonyms||PDCD4; programmed cell death 4 (neoplastic transformation inhibitor); H731; programmed cell death protein 4; protein 197/15a; nuclear antigen H731; neoplastic transformation inhibitor protein;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
pdcd4 involved in several pathways and played different roles in them. We selected most pathways pdcd4 participated on our site, such as Proteoglycans in cancer, MicroRNAs in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with pdcd4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Proteoglycans in cancer||WNT3; TWIST2; PLCG1; COL21A1; CAMK2B; PXN; ITGB3; TRP53; CTTN; CAMK2D|
|MicroRNAs in cancer||FOXP1; PIM1; TP53; BRCA1; HOXD10; FZD3; SOX4; NRAS; RPS6KA5; EFNA3|
pdcd4 has several biochemical functions, for example, RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by pdcd4 itself. We selected most functions pdcd4 had, and list some proteins which have the same functions with pdcd4. You can find most of the proteins on our site.
|RNA binding||TRIM71; SMN2; EIF4EA; APOBEC3F; KHDRBS1; RBM24A; RPL39L; CSDC2; DDX3X; FXR1|
|protein binding||COMMD7; LARP4; AHSA1; PRL; FCHSD2; RNF146; RALGDS; E2F5; RNF135; CECR2|
pdcd4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with pdcd4 here. Most of them are supplied by our site. Hope this information will be useful for your research of pdcd4.
EIF4A2; EIF4A1; RELA; EIF4A3; RPS13