PIK3CD

  • Official Full Name

    phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
  • Overview

    Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.[provided by RefSeq, Jul 2010]
  • Synonyms

    PIK3CD;phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta;APDS;PI3K;IMD14;p110D;P110DELTA;phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform;PI3Kdelta;phosphoinositide-3-kinase C;PI3-kinase p110 subunit delta;ptdIns-3-kinase subunit p110-delta;phosphoinositide-3-kinase, catalytic, delta polypeptide variant p37delta;phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta;phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform

Recombinant Proteins

  • Human
  • Zebrafish
  • Chicken
  • Sf21 Cells
  • Mammalian Cells
  • Sf9 Cells
  • HEK293
  • E.coli
  • E. coli
  • Flag
  • GST
  • His
  • Non
  • T7
Cat.# Product name Source (Host) Species Tag Protein Length Price
PIK3CD-1687HF Active Recombinant Full Length Human PIK3CD Protein, DDK-tagged, Biotinylated Sf21 Cells Human Flag Full L. 1-1044(end)
PIK3CD-8212HF Active Recombinant Full Length Human PIK3CD Protein, GST-tagged Sf21 Cells Human GST Full L. 1-1044(end)
PIK3CD-11416Z Recombinant Zebrafish PIK3CD Mammalian Cells Zebrafish His
PIK3CD-1896H Recombinant Human Phosphoinositide-3-Kinase, Catalytic, Delta Polypeptide, His-tagged Sf9 Cells Human His
PIK3CD-1989C Recombinant Chicken PIK3CD Mammalian Cells Chicken His
PIK3CD-29587TH Recombinant Human PIK3CD Human Non Full L.
PIK3CD-52H Recombinant Human PIK3CD, GST-tagged Sf9 Cells Human GST
PIK3CD-3187HCL Recombinant Human PIK3CD 293 Cell Lysate HEK293 Human Non
PIK3CD-1727H Recombinant Human PIK3CD protein, His & T7-tagged E.coli Human His&T7 Val774~Gln1044
PIK3CD-301404H Recombinant Human PIK3CD protein, GST-tagged E.coli Human GST Tyr395-Leu580
PIK3CD-4900H Recombinant Human PIK3CD Protein (Val774-Gln1044), N-His tagged E.coli Human His Val774-Gln1044
PIK3CD-8555H Recombinant Human PIK3CD protein, His-tagged E. coli Human His

    Involved Pathway

    PIK3CD involved in several pathways and played different roles in them. We selected most pathways PIK3CD participated on our site, such as Inositol phosphate metabolism,ErbB signaling pathway,Ras signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PIK3CD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    HIF- signaling pathway CUL2,Trf,HK3,INS,MKNK2,IGF1,TEK,BCL2,ALDOA,INSR
    Small cell lung cancer ITGAV,PIK3R3,PTK2,IKBKB,FHIT,CCNE2,CKS2,TP53,TRAF6,BIRC7
    cAMP signaling pathway RELA,HTR1A,FFAR2,GNAI2,GRIN2D,SLC9A1,GRIN3A,OXTR,FOS,MLLT4
    Progesterone-mediated oocyte maturation PDE3B,MAPK13,GNAI3,PRKACAA,RAF1A,MAPK11,ANAPC7,GNAI2,CDC16,MAPK9
    Focal adhesion THBS4,ITGB1,MYL12B,KDR,ITGA10,MAPK8,DIAP1,HRASA,ILK,PDGFRA
    Phosphatidylinositol signaling system PIK3C3,CDS2,SYNJ1,PIK3CB,CALM1B,CALM2,PIK3C2G,DGKE,PIK3R5,INPPL1A
    Phospholipase D signaling pathway AKT2,LPAR3,LPAR2,CXCR2,MRAS,IL-8,F2R,PIK3CB,CYTH2,DGKZ
    Toxoplasmosis RELA,TGFB2,HSPA1L,IFNGR1,BIRC2,Toxoplasma Gondii Microneme Protein MIC3,HSPA1A,TGFB3,CASP8,PIK3R5
    Thyroid hormone signaling pathway ATP1B3,CASP9,MED1,SLCO1C1,CCND1,PLCB1,MED13L,NOTCH3,PLCE1,TSC2

    Protein Function

    PIK3CD has several biochemical functions, for example, 1-phosphatidylinositol-3-kinase activity,1-phosphatidylinositol-4-phosphate 3-kinase activity,ATP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PIK3CD itself. We selected most functions PIK3CD had, and list some proteins which have the same functions with PIK3CD. You can find most of the proteins on our site.

    Function Related Protein
    1-phosphatidylinositol-4-phosphate 3-kinase activity PIK3C2A,PIK3CB,PIK3C2G,PIK3CA,PIK3C2B,PIK3CG
    ATP binding PRKACBA,MYHZ1.2,KATNA1,STK36,NLRP5,IKBKAP,ACTR8,ABCC11,MAP4K3,MOS
    protein binding GRIFIN,MAP3K1,OIP5,BATF2,UBXN2B,RIN3,CTNNBL1,PAK2,C4BPA,ATP2C2
    phosphatidylinositol-4,5-bisphosphate 3-kinase activity PIK3CB,PIK3CA,PIK3CG
    1-phosphatidylinositol-3-kinase activity PIK3C2A,ATM,PIK3C2B,PIK3R3,PIK3C2G,PIK3CG,PIK3C3,PIK3CA,PIK3CB
    phosphatidylinositol 3-kinase activity PIK3CB,PIK3C2A,PIK3CG,PIK3CA

    Interacting Protein

    PIK3CD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PIK3CD here. Most of them are supplied by our site. Hope this information will be useful for your research of PIK3CD.

    PIK3R1;1-phosphatidyl-1d-myo-inositol;pi3kr1_cerae_protein;HRAS;CD37;NCK1;TNPO2;FAM195A;ASCC2;RALY

    PIK3CD Related Signal Pathway

    Resources

    References

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