Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

PIK3CD

  • Official Full Name

    phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta

  • Overview

    Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.[provided by RefSeq, Jul 2010]
  • Synonyms

    PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta; APDS; PI3K; IMD14; p110D; P110DELTA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; PI3Kdelta; phosphoinositide-3-kinase C; PI3-kinase p110 subunit delta; ptdIns-3-kinase subunit p110-delta; phosphoinositide-3-kinase, catalytic, delta polypeptide variant p37delta; phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Chicken
  • Human
  • Zebrafish
  • E.coli
  • HEK293
  • Insect (sf21)
  • Mammalian Cell
  • Sf9 Insect Cell
  • DDK
  • GST
  • His
  • His|T7
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PIK3CD-1687HF Active Recombinant Full Length Human PIK3CD Protein, DDK-tagged, Biotinylated Insect (sf21) DDK 1-1044(end)
Human PIK3CD-8212HF Active Recombinant Full Length Human PIK3CD Protein, GST-tagged Insect (sf21) GST 1-1044(end)
Human PIK3CD-1896H Recombinant Human Phosphoinositide-3-Kinase, Catalytic, Delta Polypeptide, His-tagged Sf9 Insect Cell His
Human PIK3CD-29587TH Recombinant Human PIK3CD N/A
Human PIK3CD-52H Recombinant Human PIK3CD, GST-tagged Sf9 Insect Cell GST
Human PIK3CD-3187HCL Recombinant Human PIK3CD 293 Cell Lysate HEK293 N/A
Human PIK3CD-4900H Recombinant Human PIK3CD Protein (Val774-Gln1044), N-His tagged E.coli N-His Val774-Gln1044
Human PIK3CD-1727H Recombinant Human PIK3CD protein, His & T7-tagged E.coli His/T7 Val774~Gln1044 (Accession # O00329)
Human PIK3CD-301404H Recombinant Human PIK3CD protein, GST-tagged E.coli GST Tyr395-Leu580
Zebrafish PIK3CD-11416Z Recombinant Zebrafish PIK3CD Mammalian Cell His
Chicken PIK3CD-1989C Recombinant Chicken PIK3CD Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PIK3CD Related Research Area
  • PIK3CD Related Signal Pathway

PIK3CD involved in several pathways and played different roles in them. We selected most pathways PIK3CD participated on our site, such as Inositol phosphate metabolism, ErbB signaling pathway, Ras signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PIK3CD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Inositol phosphate metabolismPTENA;PTEN;PIKFYVE;TPI1A;INPP5K;NUDT3A;PIP5K1C;IMPA2;MTMR14
ErbB signaling pathwayPRKCA;SRC;NRG1;KRAS;PRKCBB;MAP2K7;AKT1;MAP2K2B;RAF1B
Ras signaling pathwayPLA2G6;FGF1;CALML3;Kitl;PLA2G2D;CDC42;GNG12;INS1;VEGFC
Rap signaling pathwayNGF;F2R;CALM1;FGFR3;PRKD3;RAP1GAP;MAPK13;FPR1;HGF
cGMP-PKG signaling pathwayNFATC2;PLCB4;MAP2K2;PPP3R2;CALM2;GNAI3;SLC25A6;MAP2K1;KCNMB3
cAMP signaling pathwayVIPR2;PPARA;ATP1B1;GRIA1;GRIA3;NPY;NFKBIA;GRIN2A;MAP2K2
Chemokine signaling pathwayCcl21c;PTK2;CCR8;PRKACA;CX3CL1;PPBP;GM10591;ARRB2;GRK4
HIF- signaling pathwayIGF1;RPS6KB2;NOS3;INS;TLR4;EIF4E1B;VHL;HMOX1;MKNK2
FoxO signaling pathwayMAPK8A;MAPK12B;NLK2;IL7R;SMAD4;TGFBR1B;PRKAA2;S1PR4;TGFB2
Phosphatidylinositol signaling systemCALM1A;IP6K1;PIP5K1C;MTMR7A;INPP5K;PIK3R1;CDS1;CALM4;PIP5K1BA
Sphingolipid signaling pathwayPPP2R5D;PIK3R2;BCL2;BDKRB2;DEGS2;FCER1G;PPP2R5C;ABCC1;MAP2K1
Phospholipase D signaling pathwayPLA2G4C;PDGFC;GRM8;MAPK3;SOS1;MTOR;PLCG1;HRAS;PIK3CB
mTOR signaling pathwayTSC1;DDIT4;PTENB;TSC1B;EIF4E1B;RPS6KA6;RPS6KA3A;PIK3R3B;PIK3CA
PIK-Akt signaling pathwayLAMB1;PDGFRB;F2R;LAMA5;FN1;MTOR;PHLPP2;IFNB1;GSK3B
AMPK signaling pathwayPPP2R5C;PIK3CD;AKT1;CRTC2;PCK1;CREB1;PFKFB4;CAB39;CAB39L
ApoptosisBCL2;Fasl;CDK5RAP2;PRKAR2AA;CTNNB2;STK24A;TRP53;BOKA;ADD1
Adrenergic signaling in cardiomyocytesCAMK2D2;PLCB2;CACNA1SB;TPM4B;BCL2A;TNNC1A;TPM4A;TPM3;SCN4BA
VEGF signaling pathwayMAPKAPK2A;RAC1;PRKCBB;RAC1B;SHC2;MAPK13;PTGS2A;CDC42L2;HRASB
Osteoclast differentiationMAPK8;IFNGR2;BLNK;LILRB5;MAPK3;PLCG2;LILRA1;FCGR3B;MITF
Focal adhesionPXNA;TLN2A;TNR;RAP1AB;MAP2K1;ITGA7;AKT1;VASP;STYK1
Signaling pathways regulating pluripotency of stem cellsINHBB;DLX5;WNT5B;BMPR1B;AXIN2;SMAD3;PIK3CA;WNT9A;WNT4
Platelet activationMAPK13;P2RY12;FCER1G;RAP1A;TBXAS1;ARHGEF12;Adcy4;PIK3CB;AKT1
Toll-like receptor signaling pathwayRIPK1;TMED7-TICAM2;MAPK14B;TLR8;IFNA17;MAP2K4;IFNB1;TLR1LB;IFNA16
Jak-STAT signaling pathwayIL11RA;IL29;PIAS4B;AOX3L1;Ifna11;IL10RA;BCL2;IL3;CSH1
Natural killer cell mediated cytotoxicityRAC2;IFNGR1;HLA-E;FCGR3B;TNFRSF10D;Raet1c;CD247;Ifna11;PRKCA
T cell receptor signaling pathwayPPP3R2;PAK3;MAP2K1;DEF6A;GRB2;CD8B;DBNLB;MAPK13;PIK3CG
B cell receptor signaling pathwayNEDD9;NFATC1;IFITM1;NFATC3;CARD11;LAT2;CD79A;LILRB3;DAPP1
Fc epsilon RI signaling pathwayLAT;LCP2;MAPK11;PLCG1;IL4;GM-CSF;PRKCA;AKT2;RAC2
Fc gamma R-mediated phagocytosisWASF1;ARPC1A;PPAP2A;SPHK1;PLA2G6;FCGR3A;HCK;BIN1;PTPRC
TNF signaling pathwayPGAM5;NFKBIA;MAP2K6;FOS;Ccl12;MAPK11;FAS;PIK3CB;MAP2K4
Leukocyte transendothelial migrationROCK1;CLDN6;MLLT4;VCAM1;VCL;PIK3R1;ITGB1;VASP;MMP9
Neurotrophin signaling pathwayCALM2;ZFP110;Fasl;NFKBIB;SOS1;SHC3;TP53;NFKBIA;GRB2
Cholinergic synapseKCNJ4;ATF4;PRKCA;CHRNA4;KCNQ3;GNGT1;CAMK2A;PIK3CB;GNAO1
Inflammatory mediator regulation of TRP channelsTRPA1;CALM1;CYP4A14;PTGER4;KLK1B4;ITPR1;TRPV1;Adcy4;PIK3R5
Regulation of actin cytoskeletonFGF10A;RAC1;ARPC5A;PIK3R1;ARPC5L;CYFIP1;MYLPF;INSRR;FGF6B
Insulin signaling pathwayGYS2;INPP5K;MAP2K2;PDPK1;GSK3B;TSC1A;BAD;PPP1CA;PHKG1
Progesterone-mediated oocyte maturationARAF;MAP2K1;RPS6KA3A;CPEB1A;IGF1;GNAIA;MAPK14A;RPS6KA6;PIK3R3B
Estrogen signaling pathwayGPR30;GABBR2;PIK3CA;SOS1;HSPA1B;KCNJ6;PRKACG;NOS3;SHC1
Prolactin signaling pathwaySHC4;GSK3B;SOCS2;MAPK10;SLC2A2;LHCGR;IRF1;PIK3R1;MAP2K1
Thyroid hormone signaling pathwayMAP2K2;THRB;RCAN2;RAF1;PLCB3;MDM2;PRKCB;PLCG2;PLCE1
Oxytocin signaling pathwayPRKCB;NPR1;ACTG1;PPP1R12A;PRKAG3;Adcy4;PRKAB2;CALM1;NRAS
Regulation of lipolysis in adipocytesAKT1;Adcy4;GNAS;TSHR;LOC100328615;GNAI2;PIK3CD;TSHB;FABP4
Type II diabetes mellitusHK2;CACNA1G;MAPK8;IRS4;SOCS4;IRS1;IKBKB;PRKCE;MAPK9
Insulin resistancePIK3R2;PPP1CBL;PIK3R1;INS2;MAPK8A;G6PCA.2;PPP1CAB;RPS6KA2;GYS1
Non-alcoholic fatty liver disease (NAFLD)SDHD;UQCRC2;NDUFS6;IRS1;CYCS;NDUFA4L2;PIK3CD;MLXIPL;COX7A2
Aldosterone-regulated sodium reabsorptionSCNN1B;MAPK1;ATP1B3;PRKCG;PRKCA;HSD11B2;ATP1A1;SFN;IGF1
Carbohydrate digestion and absorptionFXYD2;ATP1B2;AMY1A;AKT2;PIK3CB;ATP1B4;HKDC1;Amy1;PIK3R5
Bacterial invasion of epithelial cellsPIK3CD;MET;ARPC4;RHOG;ITGA5;DNM2;GAB1;ARPC1A;BCAR1
Chagas disease (American trypanosomiasis)PPP2R2A;CXCL8;C3;LOC100033925;TNF;PPP2R1B;GNAS;MYD88;TGFB3
ToxoplasmosisToxoplasma Gondii Profilin Family Protein;HSPA1B;HSPA6;IKBKG;SOCS1;CYCS;PIK3CG;HLA-DRB5;LAMA3
AmoebiasisARG2;PIK3R1;GNAQ;SERPINB13;TGFB1;GNAS;COL1A1;NOS2;COL5A2
Hepatitis CAKT1;OAS2;EIF2AK1;EIF3E;BRAF;SCARB1;CLDN5;CLDN9;CLDN18
Hepatitis BIFNA5;SMAD4;CREB3L2;IFNA17;HBXIP;Casp3;IFNA13;STAT6;TICAM2
MeaslesTLR7;EIF2AK1;IL2RB;DDX58;TYK2;CCND2;TNFSF10;PIK3R1;IFNA10
Influenza AIL18;BMA2;Ifna15;CCL2;IRF7;TLR7;IRF9;OAS1A;CCL5
HTLV-I infectionZFP36;STAT5A;STAT5B;VCAM1;HLA-DMB;PIK3R5;DVL1;POLD2;HLA-DRB4
Epstein-Barr virus infectionSNW1;HSPB2;IKBKB;AKT1;HDAC2;PIK3R3;POLR3F;HLA-B;POLR2J3
Pathways in cancerHDAC2;GSTP1;PDGFRA;MAPK8;PIK3CD;NCOA4;FGF11;RB1;WNT1
Viral carcinogenesisMAPKAPK2;HLA-A;CREB3L1;EP300;CREB3L2;PIK3R1;MDM2;GTF2H1;HIST1H2BD
Proteoglycans in cancerPIK3R3;PIK3CA;ACTG1;MAPK12;RPS6KB1;TRP53;PTCH1;WNT3A;MAPK1
Colorectal cancerPIK3CA;BIRC5;TGFBR2;APC2;MSH3;TRP53;MAPK10;SMAD2;MAPK8
Renal cell carcinomaEGLN1;HGF;AHA-1;PIK3CA;GRB2;HRAS;PIK3R2;CUL2;PIK3R5
Pancreatic cancerTGFB2;TRP53;PIK3CD;BCL2L1;TGFA;RELA;RAC2;RALB;MAPK1
Endometrial cancerAPC;ARAF;PIK3CA;APC2;GRB2;CDH1;AKT1;LEF1;MAP2K1
GliomaMTOR;CAMK2G;GRB2;PTEN;NRAS;PIK3R2;TGFA;PDGFA;PIK3CG
Prostate cancerPDGFB;AKT2;INS1;MDM2;CCND1;CREB3L1;PIK3CA;SOS1;PTEN
MelanomaMAPK3;FGF3;FGF8;IGF1;Pdgfa&Pdgfb;PIK3CB;PDGFB;BRAF;FGF1
Chronic myeloid leukemiaBCR;MAPK1;PIK3CG;RELA;TGFB3;GAB2;CRKL;BAD;NRAS
Acute myeloid leukemiaRARA;RPS6KB2;HRAS;EIF4EBP1;STAT3;PIK3CA;PPARD;PIK3CB;RELA
Small cell lung cancerBIRC3;ITGAV;LAMA5;PTEN;CYCS;CASP9;AKT1;RXRB;BCL2L1
Non-small cell lung cancerMAPK1;PIK3CB;FOXO3;RASSF5;AKT2;EML4;PIK3CD;CCND1;FHIT
Central carbon metabolism in cancerRET;PDHA2;HKDC1;AKT2;PDGFRB;HIF1A;KRAS;AKT1;PFKL
Choline metabolism in cancerSP1;MAP2K2;TSC2;DGKQ;MAPK1;PLA2G4C;SOS1;MTOR;RALGDS

PIK3CD has several biochemical functions, for example, 1-phosphatidylinositol-3-kinase activity, 1-phosphatidylinositol-4-phosphate 3-kinase activity, ATP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PIK3CD itself. We selected most functions PIK3CD had, and list some proteins which have the same functions with PIK3CD. You can find most of the proteins on our site.

Function Related Protein
1-phosphatidylinositol-3-kinase activityPIK3C3;PIK3C2B;PIK3C2G;PIK3CG;PIK3CB;ATM;PIK3R3;PIK3CA;PIK3C2A
1-phosphatidylinositol-4-phosphate 3-kinase activityPIK3CB;PIK3C2A;PIK3CD;PIK3CG;PIK3C2G;PIK3CA;PIK3C2B
ATP bindingRFC4;NUAK2;DAPK2;ABCA7;ABCF2A;DDX3X;CPS1;FAM20C;ATP1A3A
phosphatidylinositol 3-kinase activityPIK3CD;PIK3C2A;PIK3CG;PIK3CA;PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase activityPIK3CB;PIK3CD;PIK3CG;PIK3CA
protein bindingRHOJ;NME2;LAPTM5;RPL23;SYT1;PCGF5;ZNF2;CASR;NPEPL1

PIK3CD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PIK3CD here. Most of them are supplied by our site. Hope this information will be useful for your research of PIK3CD.

PIK3R1; 1-phosphatidyl-1d-myo-inositol; pi3kr1_cerae_protein; HRAS; CD37; NCK1; TNPO2; FAM195A; ASCC2; RALY

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All PIK3CD Products

Required fields are marked with *

My Review for All PIK3CD Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends