Plaur

  • Official Full Name

    Plasminogen Activator, Urokinase Receptor

  • Overview

    Urokinase (trade name Abbokinase), also called urokinase-type plasminogen activator (uPA), is a serine protease (EC 3.4.21.73). Urokinase was originally isolated from human urine, but is present in several physiological locations, such as blood stream and the extracellular matrix. The primary physiological substrate is plasminogen, which is an inactive zymogen form of the serine protease plasmin. Activation of plasmin triggers a proteolysis cascade that, depending on the physiological environment, participates in thrombolysis or extracellular matrix degradation. This links urokinase to vascular diseases and cancer.
  • Synonyms

    ATF; ATF uPA; Plasminogen activator; Plasminogen activator urinary; Plasminogen activator urokinase; PLAU; u PA; U plasminogen activator; U-plasminogen activator; UPA; URK; UROK_HUMAN; Urokinase plasminogen activator; Urokinase type plasminogen activator; Urokinase type plasminogen activator precursor; Urokinase-type plasminogen activator chain B;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chromatography Reagents
  • Cynomolgus
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293 cells
  • HEK293T
  • Human Cell
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Yeast
  • C
  • His
  • Fc
  • Flag
  • GST
  • His (Fc)
  • Avi
  • hFc
  • His|GST
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PLAUR-051H Active Recombinant Human PLAUR protein, His/Avi-tagged, Biotinylated HEK293 cells His/Avi Leu23-Arg303
Human PLAUR-583H Recombinant Human PLAUR protein, His-tagged E.coli His Leu13~Tyr114 (Accession # Q03405)
Human PLAUR-3861H Active Recombinant Human PLAUR, His tagged HEK293 His Met 1-Arg 303
Human PLAUR-585H Recombinant Human PLAUR protein, His & GST-tagged E.coli His/GST Gly221~Gly305 (Accession # Q03405)
Human PLAUR-412H Recombinant Human Plasminogen Activator, Urokinase Receptor Mammalian cells N/A
Human PLAUR-923H Recombinant Human PLAUR Protein, His-tagged HEK293 His
Human PLAUR-1888HCL Recombinant Human PLAUR cell lysate Human Cell N/A
Human PLAUR-1866H Recombinant Human PLAUR Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human PLAUR-725H Recombinant Human PLAUR Protein (23-305 aa), GST-tagged E.coli GST 23-305 aa
Human PLAUR-392H Recombinant Human PLAUR Protein, His-tagged E.coli N-His Leu13-Gly305
Human PLAUR-1698H-B Recombinant Human PLAUR Protein Pre-coupled Magnetic Beads HEK293
Human PLAUR-1698H Recombinant Human PLAUR Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human PLAUR-3942H Recombinant Human PLAUR Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PLAUR-472H Recombinant Human PLAUR Protein, His-tagged HEK293 His 335
Human PLAUR-0810H Recombinant Human PLAUR protein, His-tagged HEK293 His Leu209-Arg303
Human PLAUR-0809H Recombinant Human PLAUR protein, His-tagged HEK293 His Ser112-Arg303
Human PLAUR-1289H Recombinant Human PLAUR Protein (Leu23-Arg303), N-His tagged E.coli N-His Leu23-Arg303
Human PLAUR-0811H Active Recombinant Human PLAUR protein, Fc-tagged HEK293 Fc Leu23-Arg303
Human PLAUR-0812H Active Recombinant Human PLAUR protein, His-tagged, FITC-Labeled HEK293 His Leu23-Arg303
Human PLAUR-0813H Active Recombinant Human PLAUR protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Leu23-Arg303
Human PLAUR-4657H Active Recombinant Human PLAUR Protein, His-tagged, PE-Labeled HEK293 His Leu 23 - Arg 303
Human PLAUR-2607H Recombinant Human PLAUR Protein (Leu23-Arg30), His tagged E.coli His Leu23-Arg30
Human PLAUR-4927H Recombinant Human PLAUR Protein (Met1-Gly305), C-His tagged Mammalian cells C-His Met1-Gly305
Human PLAUR-342M Active PLAUR protein-coupled magnetic Beads HEK293
Human PLAUR-338HFL Active Recombinant Full Length Human PLAUR Protein, C-Flag-tagged Mammalian cells Flag
Mouse Plaur-1783M Recombinant Mouse Plasminogen Activator, Urokinase Receptor Mammalian cells N/A
Mouse Plaur-831M Active Recombinant Mouse Plaur protein, His&hFc-tagged HEK293 His&hFc Met1-Thr297
Mouse Plaur-1299M Recombinant Mouse Plasminogen Activator, Urokinase Receptor, His-tagged Insect Cell N/A
Mouse Plaur-586M Recombinant Mouse Plaur protein, His-tagged E.coli His Thr15~Asn211 (Accession # P35456)
Mouse Plaur-2304M Active Recombinant Mouse Plaur protein(Met1-Thr297), His-tagged HEK293 C-His Met1-Thr297
Mouse Plaur -83M Recombinant Soluble Mouse uPAR, His-tagged Insect Cell His
Mouse PLAUR-2551MCL Recombinant Mouse PLAUR cell lysate Human Cell N/A
Mouse Plaur-02HCL Recombinant Mouse Plaur overexpression lysate HEK293T Myc/DDK
Mouse Plaur-10609M Recombinant Mouse Plaur Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Plaur-4909M Recombinant Mouse Plaur Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse PLAUR-0808M Active Recombinant Mouse PLAUR protein, His-tagged HEK293 His Leu24-Pro296
Mouse Plaur-18HCL Recombinant Mouse Plaur overexpression lysate HEK293T Myc/DDK
Mouse Plaur-10609M-B Recombinant Mouse Plaur Protein Pre-coupled Magnetic Beads HEK293
Rat Plaur-587R Recombinant Rat Plaur protein, His-tagged E.coli His Thr17~Asn212 (Accession # P49616)
Rat PLAUR-4495R Recombinant Rat PLAUR Protein Mammalian Cell His
Rat PLAUR-726R Recombinant Rat PLAUR Protein (25-299 aa), His-tagged E.coli His 25-299 aa
Rat PLAUR-4155R-B Recombinant Rat PLAUR Protein Pre-coupled Magnetic Beads HEK293
Rat PLAUR-1488R Recombinant Rat PLAUR Protein (25-299 aa), His-tagged Yeast His 25-299 aa
Rat PLAUR-4155R Recombinant Rat PLAUR Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus PLAUR-793C Recombinant Cynomolgus PLAUR Protein, N-His-tagged HEK293 N-His
Cynomolgus Monkey PLAUR-536C-B Recombinant Cynomolgus Monkey PLAUR Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey PLAUR-536C Recombinant Cynomolgus Monkey PLAUR Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

Plaur involved in several pathways and played different roles in them. We selected most pathways Plaur participated on our site, such as Complement and coagulation cascades, Proteoglycans in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with Plaur were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Complement and coagulation cascadesBDKRB1;CR1L;C2;C7;PROS1;C8B;C1RA;MASP2;Serpina1b
Proteoglycans in cancerELK1;VEGFA;SRC;THBS1;TWIST2;ITGAV;CAMK2A;HSPG2;ANK2

Plaur has several biochemical functions, for example, enzyme binding, protein binding, protein domain specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Plaur itself. We selected most functions Plaur had, and list some proteins which have the same functions with Plaur. You can find most of the proteins on our site.

Function Related Protein
enzyme bindingDYM;MLEC;H2AFX;UBE4B;ATP2A2;Txn1;APOA5;GSTM3;MDM4
protein bindingKRT1;UBE2Z;MAST2;FCGR1A;PCBP2;SPEF2;TAF1D;TBX24;MACROD1
protein domain specific bindingANGEL1;CSNK2B;EHD2;YWHABL;HAND2;VPS4A;CEP68;YWHAQA;ESRRA
receptor activityPVRL2L;GRIA3A;CMKLR1;CD226;CD160;CD7;V1RA8;VMN1R46;CD5
receptor bindingCNPY4;RSPO3;TAC3;PGR;ALCAM;KNG1;SCP2;ACOX2;SERPINE1
urokinase plasminogen activator receptor activity

Plaur has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Plaur here. Most of them are supplied by our site. Hope this information will be useful for your research of Plaur.

PFN2; SUMO2; EEF1A1; SURF2

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