Recombinant Human PLAUR protein, His & GST-tagged
Cat.No. : | PLAUR-585H |
Product Overview : | Recombinant Human PLAUR aa. (Gly221~Gly305 (Accession # Q03405)) fused with N-terminal His & GST tag was produced in E. coli cells. |
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Description : | This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. |
Source : | E. coli |
Species : | Human |
Tag : | His & GST |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 41.1kDa |
Protein length : | Gly221~Gly305 (Accession # Q03405) |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | >95% |
Characteristic : | The isoelectric point is 6.7. |
Applications : | SDS-PAGE; WB; ELISA; IP |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in 20mM Tris, 500mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Gene Name : | PLAUR plasminogen activator, urokinase receptor [ Homo sapiens (human) ] |
Official Symbol : | PLAUR |
Synonyms : | PLAUR; plasminogen activator, urokinase receptor; CD87; UPAR; URKR; U-PAR; urokinase plasminogen activator surface receptor; monocyte activation antigen Mo3; u-plasminogen activator receptor form 2; urokinase-type plasminogen activator (uPA) receptor |
Gene ID : | 5329 |
mRNA Refseq : | NM_001005376.2 |
Protein Refseq : | NP_001005376.1 |
UniProt ID : | Q03405 |
Products Types
◆ Recombinant Protein | ||
PLAUR-392H | Recombinant Human PLAUR Protein, His-tagged | +Inquiry |
Plaur-18HCL | Recombinant Mouse Plaur overexpression lysate | +Inquiry |
Plaur-02HCL | Recombinant Mouse Plaur overexpression lysate | +Inquiry |
PLAUR-472H | Recombinant Human PLAUR Protein, His-tagged | +Inquiry |
PLAUR-725H | Recombinant Human PLAUR Protein (23-305 aa), GST-tagged | +Inquiry |
◆ Lysates | ||
PLAUR-2551MCL | Recombinant Mouse PLAUR cell lysate | +Inquiry |
PLAUR-1888HCL | Recombinant Human PLAUR cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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