S1PR1

  • Official Full Name

    S1PR1 sphingosine-1-phosphate receptor 1

  • Synonyms

    S1PR1; sphingosine-1-phosphate receptor 1; EDG1, endothelial differentiation, sphingolipid G protein coupled receptor, 1; sphingosine 1-phosphate receptor 1; CD363; D1S3362; edg 1; S1P receptor 1; S1P receptor Edg-1; sphingosine 1-phosphate receptor EDG1; sphingosine 1-phosphate receptor Edg-1; endothelial differentiation G-protein coupled receptor 1; endothelial differentiation, sphingolipid G-protein-coupled receptor, 1; EDG1; S1P1; ECGF1; EDG-1; CHEDG1; FLJ58121;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Bos taurus (Bovine)
    • Danio rerio (Zebrafish) (Brachydanio rerio)
    • Homo sapiens (Human)
    • Human
    • Mouse
    • Mus musculus (Mouse)
    • Rat
    • Rattus norvegicus (Rat)
    • Zebrafish
    • Source :
    • E.coli
    • E.coli expression system
    • HEK293
    • In Vitro Cell Free System
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • His (Fc)
    • Avi
    • Flag
    • N/A
    • N
    Species Cat.# Product name Source (Host) Tag Price
    Human S1PR1-569H Recombinant Human S1PR1 Mammalian Cell His
    Human S1PR1-28462TH Recombinant Human S1PR1 protein Wheat Germ N/A
    Human S1PR1-4038H Recombinant Human S1PR1 Protein, GST-tagged Wheat Germ GST
    Human S1PR1-530HCL Recombinant Human S1PR1 cell lysate N/A
    Human S1PR1-4725HF Recombinant Full Length Human S1PR1 Protein, GST-tagged In Vitro Cell Free System GST
    Human S1PR1-1118HFL Recombinant Human S1PR1 protein, His&Flag-tagged HEK293 His&Flag
    Human S1PR1-4023H Recombinant Human S1PR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Human S1PR1-4023H-B Recombinant Human S1PR1 Protein Pre-coupled Magnetic Beads HEK293
    Mouse S1PR1-14628M Recombinant Mouse S1PR1 Protein Mammalian Cell His
    Mouse S1PR1-7871M-B Recombinant Mouse S1PR1 Protein Pre-coupled Magnetic Beads HEK293
    Mouse S1pr1-2041M Recombinant Mouse S1pr1 Protein, His-tagged E.coli N-His
    Mouse S1PR1-7871M Recombinant Mouse S1PR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rat S1PR1-5219R Recombinant Rat S1PR1 Protein Mammalian Cell His
    Rat S1PR1-4878R Recombinant Rat S1PR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rat S1PR1-4878R-B Recombinant Rat S1PR1 Protein Pre-coupled Magnetic Beads HEK293
    Bos taurus (Bovine) RFL955BF Recombinant Full Length Bovine Sphingosine 1-Phosphate Receptor 1(S1Pr1) Protein, His-Tagged E.coli expression system His
    Danio rerio (Zebrafish) (Brachydanio rerio) RFL15845DF Recombinant Full Length Danio Rerio Sphingosine 1-Phosphate Receptor 1(S1Pr1) Protein, His-Tagged E.coli expression system His
    Homo sapiens (Human) RFL1995HF Recombinant Full Length Human Sphingosine 1-Phosphate Receptor 1(S1Pr1) Protein, His-Tagged E.coli expression system His
    Mus musculus (Mouse) RFL7405MF Recombinant Full Length Mouse Sphingosine 1-Phosphate Receptor 1(S1Pr1) Protein, His-Tagged E.coli expression system His
    Rattus norvegicus (Rat) RFL31955RF Recombinant Full Length Rat Sphingosine 1-Phosphate Receptor 1(S1Pr1) Protein, His-Tagged E.coli expression system His
    Zebrafish S1PR1-9218Z Recombinant Zebrafish S1PR1 Mammalian Cell His
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • S1PR1 Related Articles
    • S1PR1 Related Gene Family
    • S1PR1 Related Research Area

    S1PR1 involved in several pathways and played different roles in them. We selected most pathways S1PR1 participated on our site, such as Class A/1 (Rhodopsin-like receptors), Fc-epsilon receptor I signaling in mast cells, FoxO signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with S1PR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Class A/1 (Rhodopsin-like receptors)INSL3;ACKR4;TAAR1;CNR1;CXCR7B;SSTR4;OPN4.1;PMCH;MLN
    Fc-epsilon receptor I signaling in mast cellsS1PR1;ITK;LAT2;DOK1;PTPN13
    FoxO signaling pathwayPRKAG3B;GRB2B;PLK1;FOXO4;PLK4;HOMER1B;INSRA;EGFRA;NLK
    G alpha (i) signalling eventsADORA3;CHRM4;SSTR4;GPR55;GPR17;CCL35.1;RGR;LPAR2A;RLN3A
    GPCR downstream signalingRLN3;TRPC3;GPBAR1;SOUL3;TRH;DRD2;RGS10;RLN3A;S1PR1
    GPCR ligand bindingCHRM1;CCL19A.2;EMR2;PROKR2;EDN2;CHRM4;CALCA;OPN1MW2;GNB5B
    GPCRs, OtherRRH;EMR3;GPR88;GPR55;PROKR2;GPR116;V1RA8;VMN1R45;GPR183
    Lysosphingolipid and LPA receptorsS1PR3;LPAR2B;LPAR2A;S1PR5B;LPAR5A;S1PR1

    S1PR1 has several biochemical functions, for example, G-protein coupled receptor activity, G-protein coupled receptor binding, sphingolipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by S1PR1 itself. We selected most functions S1PR1 had, and list some proteins which have the same functions with S1PR1. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled receptor activityGPR128;HCAR1-2;OLFR13;S1PR2;MRGPRB8;GPR182;TAS2R139;PPYR1;FZD8
    G-protein coupled receptor bindingGNA12A;UCN3L;ADORA1;APLN;GHRL;GNA13B;PSAPL1;GNAT3;GNAI2
    sphingolipid bindingS1PR1;TRAF2
    sphingosine-1-phosphate receptor activityS1PR3A;S1PR1;GPR6;S1PR5A;S1PR5;SPHK2;SPHK1;S1PR5B;S1PR2

    S1PR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with S1PR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of S1PR1.

    S1PR2; SP1; CMSS1

    Al-Jarallah, A; Chen, X; et al. High Density Lipoprotein Stimulated Migration of Macrophages Depends on the Scavenger Receptor Class B, Type I, PDZK1 and Akt1 and Is Blocked by Sphingosine 1 Phosphate Receptor Antagonists. PLOS ONE 9:-(2014).
    Tanaka, K; Hashizume, M; et al. Anti-interleukin-6 receptor antibody prevents systemic bone mass loss via reducing the number of osteoclast precursors in bone marrow in a collagen-induced arthritis model. CLINICAL AND EXPERIMENTAL IMMUNOLOGY 175:172-180(2014).
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