S1PR1
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Official Full Name
S1PR1 sphingosine-1-phosphate receptor 1
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Synonyms
S1PR1; sphingosine-1-phosphate receptor 1; EDG1, endothelial differentiation, sphingolipid G protein coupled receptor, 1; sphingosine 1-phosphate receptor 1; CD363; D1S3362; edg 1; S1P receptor 1; S1P receptor Edg-1; sphingosine 1-phosphate receptor EDG1; sphingosine 1-phosphate receptor Edg-1; endothelial differentiation G-protein coupled receptor 1; endothelial differentiation, sphingolipid G-protein-coupled receptor, 1; EDG1; S1P1; ECGF1; EDG-1; CHEDG1; FLJ58121;
- Involved Pathway
- Protein Function
- Interacting Protein
- S1PR1 Related Articles
- S1PR1 Related Gene Family
- S1PR1 Related Research Area
S1PR1 involved in several pathways and played different roles in them. We selected most pathways S1PR1 participated on our site, such as Class A/1 (Rhodopsin-like receptors), Fc-epsilon receptor I signaling in mast cells, FoxO signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with S1PR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Class A/1 (Rhodopsin-like receptors) | INSL3;ACKR4;TAAR1;CNR1;CXCR7B;SSTR4;OPN4.1;PMCH;MLN |
| Fc-epsilon receptor I signaling in mast cells | S1PR1;ITK;LAT2;DOK1;PTPN13 |
| FoxO signaling pathway | PRKAG3B;GRB2B;PLK1;FOXO4;PLK4;HOMER1B;INSRA;EGFRA;NLK |
| G alpha (i) signalling events | ADORA3;CHRM4;SSTR4;GPR55;GPR17;CCL35.1;RGR;LPAR2A;RLN3A |
| GPCR downstream signaling | RLN3;TRPC3;GPBAR1;SOUL3;TRH;DRD2;RGS10;RLN3A;S1PR1 |
| GPCR ligand binding | CHRM1;CCL19A.2;EMR2;PROKR2;EDN2;CHRM4;CALCA;OPN1MW2;GNB5B |
| GPCRs, Other | RRH;EMR3;GPR88;GPR55;PROKR2;GPR116;V1RA8;VMN1R45;GPR183 |
| Lysosphingolipid and LPA receptors | S1PR3;LPAR2B;LPAR2A;S1PR5B;LPAR5A;S1PR1 |
S1PR1 has several biochemical functions, for example, G-protein coupled receptor activity, G-protein coupled receptor binding, sphingolipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by S1PR1 itself. We selected most functions S1PR1 had, and list some proteins which have the same functions with S1PR1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-protein coupled receptor activity | GPR128;HCAR1-2;OLFR13;S1PR2;MRGPRB8;GPR182;TAS2R139;PPYR1;FZD8 |
| G-protein coupled receptor binding | GNA12A;UCN3L;ADORA1;APLN;GHRL;GNA13B;PSAPL1;GNAT3;GNAI2 |
| sphingolipid binding | S1PR1;TRAF2 |
| sphingosine-1-phosphate receptor activity | S1PR3A;S1PR1;GPR6;S1PR5A;S1PR5;SPHK2;SPHK1;S1PR5B;S1PR2 |
S1PR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with S1PR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of S1PR1.
S1PR2; SP1; CMSS1
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