Recombinant Full Length Human S1PR1 Protein, GST-tagged

• Cat.No.: S1PR1-4725HF
• Product Overview: Human EDG1 full-length ORF ( NP_001391.2, 1 a.a. - 382 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 69.2 kDa
• Protein Length: 382 amino acids
• AA Sequence: MGPTSVPLVKAHRSSVSDYVNYDII VRHYNYTGKLNISADKENSIKLTSV VFILICCFIILENIFVLLTIWKTKK FHRPMYYFIGNLALSDLLAGVAYTA NLLLSGATTYKLTPAQWFLREGSMF VALSASVFSLLAIAIERYITMLKMK LHNGSNNFRLFLLISACWVISLILG GLPIMGWNCISALSSCSTVLPLYHK HYILFCTTVFTLLLLSIVILYCRIY SLVRTRSRRLTFRKNISKASRSSEK SLALLKTVIIVLSVFIACWAPLFIL LLLDVGCKVKTCDILFRAEYFLVLA VLNSGTNPIIYTLTNKEMRRAFIRI MSCCKCPSGDSAGKFKRPIIAGMEF SRSKSDNSSHPQKDEGDNPETIMSS GNVNSSS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: S1PR1 sphingosine-1-phosphate receptor 1 [ Homo sapiens ]
• Official Symbol: S1PR1
• Synonyms: S1PR1; sphingosine-1-phosphate receptor 1; EDG1, endothelial differentiation, sphingolipid G protein coupled receptor, 1; sphingosine 1-phosphate receptor 1; CD363; D1S3362; edg 1; S1P receptor 1; S1P receptor Edg-1; sphingosine 1-phosphate receptor EDG1; sphingosine 1-phosphate receptor Edg-1; endothelial differentiation G-protein coupled receptor 1; endothelial differentiation, sphingolipid G-protein-coupled receptor, 1; EDG1; S1P1; ECGF1; EDG-1; CHEDG1; FLJ58121
• Gene ID: 1901
• mRNA Refseq: NM_001400
• Protein Refseq: NP_001391
• MIM: 601974
• UniProt ID: P21453