Recombinant Full Length Mouse Sphingosine 1-Phosphate Receptor 1(S1Pr1) Protein, His-Tagged

Cat.No. : RFL7405MF
Product Overview : Recombinant Full Length Mouse Sphingosine 1-phosphate receptor 1(S1pr1) Protein (O08530) (1-382aa), fused to N-terminal His tag, was expressed in E. coli.
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  • Gene Information
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Source : E.coli expression system
Species : Mus musculus (Mouse)
Tag : His
Form : Lyophilized powder
Protein length : Full Length (1-382)
AA Sequence : MVSTSIPEVKALRSSVSDYGNYDII VRHYNYTGKLNIGAEKDHGIKLTSV VFILICCFII LENIFVLLTIWKTKKFHRPMYYFIG NLALSDLLAGVAYTANLLLSGATTY KLTPAQWFLR EGSMFVALSASVFSLLAIAIERYIT MLKMKLHNGSNSSRSFLLISACWVI SLILGGLPIM GWNCISSLSSCSTVLPLYHKHYILF CTTVFTLLLLSIVILYCRIYSLVRT RSRRLTFRKN ISKASRSSEKSLALLKTVIIVLSVF IACWAPLFILLLLDVGCKAKTCDIL YKAEYFLVLA VLNSGTNPIIYTLTNKEMRRAFIRI VSCCKCPNGDSAGKFKRPIIPGMEF SRSKSDNSSH PQKDDGDNPETIMSSGNVNSSS
Purity : Greater than 90% as determined by SDS-PAGE.
Applications : SDS-PAGE
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Storage : Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Storage Buffer : Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution : We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Gene Name : S1pr1
Synonyms : S1pr1; Edg1; Lpb1; Sphingosine 1-phosphate receptor 1; S1P receptor 1; S1P1; Endothelial differentiation G-protein coupled receptor 1; Lysophospholipid receptor B1; Sphingosine 1-phosphate receptor Edg-1; S1P receptor Edg-1; CD antigen CD363
UniProt ID : O08530
Gene Name : S1pr1
Synonyms : S1pr1; Edg1; Lpb1; Sphingosine 1-phosphate receptor 1; S1P receptor 1; S1P1; Endothelial differentiation G-protein coupled receptor 1; Lysophospholipid receptor B1; Sphingosine 1-phosphate receptor Edg-1; S1P receptor Edg-1; CD antigen CD363
UniProt ID : O08530

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Does the expression of S1PR1 vary among different tissues? 03/09/2020

Yes, the expression of S1PR1 can vary among tissues, and understanding this tissue-specific expression is important for targeted therapeutic approaches.

How does S1PR1 modulation impact the central nervous system? 08/15/2019

Modulation of S1PR1 can influence neuroinflammation and may be relevant in the treatment of neurological disorders, such as multiple sclerosis.

Is S1PR1 involved in the regulation of inflammatory responses? 01/11/2019

Yes, S1PR1 plays a role in modulating inflammatory responses, and targeting it is explored as a strategy in autoimmune and inflammatory diseases.

Can S1PR1 be a therapeutic target for cardiovascular diseases? 04/16/2018

Yes, the involvement of S1PR1 in vascular development and its impact on cardiovascular function make it a potential target for cardiovascular disease treatment.

Are there any side effects associated with drugs targeting S1PR1? 01/31/2018

Drugs targeting S1PR1 may have side effects, including cardiovascular effects and increased susceptibility to infections, which need to be carefully monitored.

Customer Reviews (3)

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Reviews
08/11/2020

    The S1PR1 protein has demonstrated remarkable stability, allowing for extended storage without compromising its quality.

    10/07/2018

      One notable advantage of the S1PR1 protein is the outstanding technical support provided by the manufacturer.

      03/04/2017

        One aspect that sets the S1PR1 protein apart is the excellent technical support provided by the manufacturer.

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