Recombinant Rat S1PR1 Protein, His (Fc)-Avi-tagged

• Cat.No.: S1PR1-4878R
• Product Overview: Recombinant Rat S1PR1 with His (Fc)-Avi tag was expressed and purified

Specification

• Source: HEK293
• Species: Rat
• Tag: His&Fc&Avi
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: ≥85% by SDS-PAGE
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: S1pr1 sphingosine-1-phosphate receptor 1 [ Rattus norvegicus ]
• Official Symbol: S1PR1
• Gene ID: 29733
• mRNA Refseq: NM_017301.2
• Protein Refseq: NP_058997.1
• UniProt ID: P48303

Reviews

08/11/2020

The S1PR1 protein has demonstrated remarkable stability, allowing for extended storage without compromising its quality.

10/07/2018

One notable advantage of the S1PR1 protein is the outstanding technical support provided by the manufacturer.

03/04/2017

One aspect that sets the S1PR1 protein apart is the excellent technical support provided by the manufacturer.

Q&As

Does the expression of S1PR1 vary among different tissues?

Yes, the expression of S1PR1 can vary among tissues, and understanding this tissue-specific expression is important for targeted therapeutic approaches.

How does S1PR1 modulation impact the central nervous system?

Modulation of S1PR1 can influence neuroinflammation and may be relevant in the treatment of neurological disorders, such as multiple sclerosis.

Is S1PR1 involved in the regulation of inflammatory responses?

Yes, S1PR1 plays a role in modulating inflammatory responses, and targeting it is explored as a strategy in autoimmune and inflammatory diseases.

Can S1PR1 be a therapeutic target for cardiovascular diseases?

Yes, the involvement of S1PR1 in vascular development and its impact on cardiovascular function make it a potential target for cardiovascular disease treatment.

Are there any side effects associated with drugs targeting S1PR1?

Drugs targeting S1PR1 may have side effects, including cardiovascular effects and increased susceptibility to infections, which need to be carefully monitored.