Recombinant Mouse S1pr1 Protein, His-tagged

• Cat.No.: S1pr1-2041M
• Product Overview: Recombinant Mouse S1pr1 Protein (Tyr311-Ser382) with N-His tag was expressed in E. coli.

Specification

• Description: This gene encodes a G-protein-coupled receptor bound by the lysophospholipid, sphingosine 1-phosphate. The gene product functions in endothelial cells and is involved in vascular and heart development. This receptor is highly expressed in T and B lymphocytes, and it plays a role in T cell and B cell export from peripheral lymphoid organs. This protein is bound and downregulated by FTY720, an exogenous immunosuppressant drug studied in mouse disease models for multiple sclerosis in humans.
• Source: E. coli
• Species: Mouse
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 11.6kD
  Accurate Molecular Mass: 16 kDa
• Protein length: Tyr311-Ser382
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: S1pr1 sphingosine-1-phosphate receptor 1 [ Mus musculus (house mouse) ]
• Official Symbol: S1pr1
• Synonyms: S1PR1; sphingosine-1-phosphate receptor 1; sphingosine 1-phosphate receptor 1; S1P receptor 1; S1P receptor Edg-1; lysophospholipid receptor B1; sphingosine 1-phosphate receptor Edg-1; endothelial differentiation G-protein coupled receptor 1; endothelial differentiation sphingolipid G-protein-coupled receptor 1; S1p; Edg1; Lpb1; S1p1; AI849002
• Gene ID: 13609
• mRNA Refseq: NM_007901
• Protein Refseq: NP_031927
• UniProt ID: O08530