SYP
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Official Full Name
Synaptophysin
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Overview
Defects in SYP are the cause of mental retardation X-linked SYP-related (MRXSYP) [MIM:300802]. Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. -
Synonyms
Major synaptic vesicle protein P38; Syn p38; Synaptophysin; SYP; SYPH; SypI;
- Recombinant Proteins
- Cell & Tissue Lysates
- Antibody
- Protein Pre-coupled Magnetic Beads
- Bos taurus (Bovine)
- Homo sapiens (Human)
- Human
- Rat
- Rattus norvegicus (Rat)
- Rhesus Macaque
- Spermophilus citellus (European suslik) (Citellus citellus)
- E. coli
- E.coli
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- In vitro E. coli expression system
- Mammalian Cell
- Mouse
- Wheat Germ
- His
- His (Fc)
- Avi
- N/A
- N
- SUMO
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | SYP-31490TH | Recombinant Human SYP | Wheat Germ | N/A | 313 amino acids | |
Human | SYP-3076H | Recombinant Human SYP, His-tagged | E.coli | His | 50-313aa | |
Human | SYP-1313HCL | Recombinant Human SYP 293 Cell Lysate | HEK293 | N/A | ||
Human | SYP-2747H | Recombinant Human SYP Protein, His-tagged | E.coli | N-His | Glu50-Phe106 | |
Human | SYP-513HF | Recombinant Full Length Human SYP Protein | In Vitro Cell Free System | 313 amino acids | ||
Human | SYP-6387H | Recombinant Human SYP Protein (Glu50-Met313), N-His tagged | E.coli | N-His | Glu50-Met313 | |
Human | CPB-922MH | Mouse Anti-Human Synaptophysin Monoclonal Antibody | Mouse | N/A | ||
Human | SYP-2596H | Recombinant Human SYP protein(228-313 aa), N-SUMO & N-His-tagged | E. coli | N-SUMO & N-His | 228-313 aa | |
Rat | SYP-5874R | Recombinant Rat SYP Protein | Mammalian Cell | His | ||
Rat | SYP-5533R | Recombinant Rat SYP Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | SYP-5533R-B | Recombinant Rat SYP Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | Syp-0148R | Recombinant Rat Syp Full Length Transmembrane protein, His-tagged | In vitro E. coli expression system | His | 1-307aa | |
Bos taurus (Bovine) | RFL20132BF | Recombinant Full Length Bovine Synaptophysin(Syp) Protein, His-Tagged | E.coli expression system | His | Full Length (1-313) | |
Homo sapiens (Human) | RFL735HF | Recombinant Full Length Human Synaptophysin(Syp) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (224-313) | |
Rattus norvegicus (Rat) | RFL17140RF | Recombinant Full Length Rat Synaptophysin(Syp) Protein, His-Tagged | E.coli expression system | His | Full Length (1-307) | |
Rhesus Macaque | SYP-4587R | Recombinant Rhesus monkey SYP Protein, His-tagged | Mammalian Cell | His | ||
Rhesus Macaque | SYP-4403R | Recombinant Rhesus Macaque SYP Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rhesus Macaque | SYP-4403R-B | Recombinant Rhesus Macaque SYP Protein Pre-coupled Magnetic Beads | HEK293 | |||
Spermophilus citellus (European suslik) (Citellus citellus) | RFL33831SF | Recombinant Full Length Spermophilus Citellus Synaptophysin(Syp) Protein, His-Tagged | E.coli expression system | His | Full Length (1-307) |
- Involved Pathway
- Protein Function
- Interacting Protein
- SYP Related Articles
- SYP Related Research Area
SYP involved in several pathways and played different roles in them. We selected most pathways SYP participated on our site, such as Synaptic Vesicle Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SYP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Synaptic Vesicle Pathway | SYN3;STX1B;SYN2;PARK7;SYP;CPLX2;SYN1;DNM1L |
SYP has several biochemical functions, for example, SH2 domain binding, cholesterol binding, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SYP itself. We selected most functions SYP had, and list some proteins which have the same functions with SYP. You can find most of the proteins on our site.
Function | Related Protein |
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SH2 domain binding | PAG1;SRC;CTR9;ARHGAP5;JAK2;SYNGR3;NLK;CRK;PTK2 |
cholesterol binding | PTCH1;ABCA1;SYP;STAR;OSBPL8;APOEA;APOA5;APOA4A;APOD |
identical protein binding | KCNJ10;PYDC3;WAS;LCP1;SMAD4;PRKD1;PAFAH1B3;IFIT3;LYZ2 |
protein self-association | PTH1R;SVIP;ADAM8;PCSK9;SLC2A1;NKX3-1;TP53;ZKSCAN17;AGTR1A |
transporter activity | TIMM9;SLC5A9;ABCA13;SLC22A17;AQP9B;PMP2;SYP;SLC5A3A;SLC2A9L1 |
SYP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SYP here. Most of them are supplied by our site. Hope this information will be useful for your research of SYP.
HTT
- Q&As
- Reviews
Q&As (7)
Ask a questionGenetic mutations in SYP can lead to impaired synaptic transmission, affecting neuronal communication.
SYP is involved in synaptic vesicle trafficking, essential for efficient neurotransmitter release and synaptic function.
SYP, or Synaptophysin, is essential for facilitating synaptic transmission in neurons.
SYP interacts with other synaptic proteins, coordinating vesicle dynamics and neurotransmitter release.
It plays a crucial role in the release of neurotransmitters by regulating synaptic vesicle fusion.
Altered SYP activity is linked to the progression of neurodegenerative diseases due to its role in synaptic function.
Targeting SYP could offer new treatments for neurological disorders by improving synaptic transmission.
Customer Reviews (3)
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