TARDBP Protein

September 27-30, 2022

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Booth #336

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TARDBP

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TARDBP

Official Full Name TAR DNA binding protein
Background HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008]
Synonyms TARDBP; TAR DNA binding protein; ALS10; TDP-43; TAR DNA-binding protein 43; TAR DNA-binding protein-43;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mamanlian cells
    • Mammalian Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Yeast
    • Tag :
    • DDK
    • Flag
    • GST
    • His
    • His-SUMO
    • Myc/DDK
    • Myc
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TARDBP-85H Recombinant Human TARDBP, His-tagged E.coli His
    Human TARDBP-2993H Recombinant Human TAR DNA Binding Protein, T7-tagged E.coli T7
    Human TARDBP-30150TH Recombinant Human TARDBP E.coli N/A
    Human TARDBP-3114H Recombinant Human TARDBP, His-tagged E.coli His
    Human TARDBP-35H Recombinant Human TARDBP, MYC/DDK-tagged HEK293 Myc/DDK
    Human TARDBP-36H Recombinant Human TARDBP, DDK-tagged Sf9 Insect Cell DDK
    Human TARDBP-39H Recombinant Human TARDBP protein, GST-tagged E.coli GST
    Human TARDBP-40H Recombinant Human TARDBP protein, GST-tagged E.coli GST
    Human TARDBP-4735H Recombinant Human TARDBP, GST-tagged Wheat Germ GST
    Human TARDBP-7588H Recombinant Human TARDBP, His-tagged E.coli His
    Mouse Tardbp-2006M Recombinant Mouse Tardbp protein, His-tagged E.coli His
    Chicken TARDBP-2569C Recombinant Chicken TARDBP Mammalian Cell His
    Zebrafish TARDBP-11522Z Recombinant Zebrafish TARDBP Mammalian Cell His
    Human TARDBP-1251HCL Recombinant Human TARDBP 293 Cell Lysate HEK293 N/A
    Human TARDBP-116H Recombinant Human TARDBP Protein, GST-tagged E.coli GST
    Human TARDBP-3345HFL Recombinant Full Length Human TARDBP, Flag-tagged Mamanlian cells Flag
    Human TARDBP-3552H Recombinant Human TARDBP protein, His-SUMO-tagged E.coli His-SUMO
    Human TARDBP-1429H Recombinant Human TARDBP Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human TARDBP-2192H Recombinant Human TARDBP Protein (1-396 aa), His-tagged Yeast His
    Human TARDBP-22H Recombinant Human TARDBP Protein E.coli N/A
    Mouse Tardbp-6294M Recombinant Mouse Tardbp Protein, Myc/DDK-tagged HEK293T Myc/DDK

    TARDBP involved in several pathways and played different roles in them. We selected most pathways TARDBP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TARDBP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    TARDBP has several biochemical functions, for example, RNA binding, double-stranded DNA binding, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TARDBP itself. We selected most functions TARDBP had, and list some proteins which have the same functions with TARDBP. You can find most of the proteins on our site.

    Function Related Protein
    RNA binding SYNJ2; DHX36; TIMM50; PCBP3; HNRNPH3; ZFP36L3; CPEB1B; KHDC3L; KIAA0907; EIF4G2B
    double-stranded DNA binding TP73; MEN1; AIM2; APTX; GATA1A; SP8B; USF1; TRP63; KIN; MTERFD1
    identical protein binding SOD1; EIF2AK3; TRIM39; IIGP1; CSNK2B; RALYL; CLDN9; CEACAM5; COL2A1; WAS
    mRNA 3-UTR binding IGF2BP2; IGF2BP1; RNF20; SECISBP2; PUM1; LARP1; AUH; ANGEL2; HNRNPC; ELAVL1
    nucleotide binding UCK2A; HHATL; ARL4AA; ATP2B3B; ATP1A2A; U2AF1L4; FUS; EIF3B; PET112L; SEPT8B
    poly(A) RNA binding CHTOP; HIST1H4L; R3HDM2; ETF1A; MKRN2; MATR3; SNRPA1; BOP1; NMD3; TRMT1
    protein binding SCNM1; XPO6; RNF213; PIK3R2; COA5; HOMER3; FUBP1; ECD; SLC1A2; CYB561
    transcription factor activity, sequence-specific DNA binding ZSCAN20; ZNF461; RELA; RFX3; RERE; MNT; TCF3; PCGF6; TSC22D4; HOXA6
    transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding ARID3B; SUB1; CDX1; PBX3; SIX6; HMGA1; TARDBP; PROP1; RELA; SIX3

    TARDBP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TARDBP here. Most of them are supplied by our site. Hope this information will be useful for your research of TARDBP.

    IRAK2; HLA-B

    Droppelmann, CA; Wang, J; et al. Detection of a novel frameshift mutation and regions with homozygosis within ARHGEF28 gene in familial amyotrophic lateral sclerosis. AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION 14:444-451(2013).
    El-Assaad, I; Di Bari, JA; et al. Differential expression of TAR DNA-binding protein (TDP-43) in the central nervous system of horses afflicted with equine motor neuron disease (EMND): a preliminary study of a potential pathologic marker. VETERINARY RESEARCH COMMUNICATIONS 36:221-226(2012).

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