TF Protein


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Official Full Name transferrin
Background This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009] Transferrin is a metal-combining protein that reversibly bound to acid-soluble iron in plasma. It functions to transport iron to the bone marrow and to tissue storage organs such as the liver. Transferrin also participate in the regulation and control of iron absorption and protects against iron intoxication. Like haptoglobin, the carrier of hemoglobin, transferrin is synthesized in the liver, but unlike haptoglobin transferrin is returned to the circulation after unloading its iron in the reticuloendothelial system. This ELISA kit can be used to measure transferrin in serum, tissue extracts and other biological fluids.
Synonyms TF; transferrin; TFQTL1; PRO1557; PRO2086; serotransferrin; siderophilin; beta-1 metal-binding globulin; AI266983; Cd176; HP; Tfn; hpx; hypotransferrinemia with hemochromatosis; Apotransferrin; Beta 1 metal binding globulin; DKFZp781D0156; PRO1400; Serotransferrin precursor; Transferin; TRFE_HUMAN
    • Species :
    • Bovine
    • Cattle
    • Chicken
    • Dog
    • Gallus gallus (chicken)
    • Human
    • Monkey
    • Mouse
    • Pig
    • Rabbit
    • Rat
    • Sheep
    • Source :
    • Bovine Serum
    • Cattle
    • Chicken Egg White
    • Chicken Serum
    • Conalbumin from Chicken egg white
    • E.coli
    • HEK293
    • Human
    • Human Cell
    • Human Plasma
    • Human Serum
    • Mammalian Cell
    • Monkey plasma
    • Mouse Plasma
    • Mouse Serum
    • Oryza Sativa
    • Pig
    • Rabbit Skeletal Muscle
    • Rat
    • Rat Plasma
    • Serum
    • Sheep Serum
    • Tag :
    • Fc
    • GST
    • His
    • His-KSI
    • Mouse
    • IgG2a
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Bovine TF-01B Native Bovine TF Protein
    Rat Tf-3563R Recombinant Rat Tf protein, His-KSI-tagged E.coli His-KSI
    Human TF-001H Recombinant Human TF Protein Oryza Sativa
    Human TF-002H Native Human TF Protein, Rhodamine Conjugated Serum N/A
    Human TF-03H Recombinant Human Transferrin Oryza Sativa N/A
    Human TF-056H Recombinant Human TF Protein, His-tagged HEK293 His
    Human TF-102H Native Human Transferrin (HOLO) Human Plasma N/A
    Human TF-103H Native Human Apotransferrin Human Plasma N/A
    Human TF-147H Recombinant Human TF Protein, His-tagged E.coli His
    Human TF-2351H Recombinant Human TF, His tagged Human Cell His
    Human TF-24H Human Transferrin Reference Standard N/A
    Human TF-2542HCL Recombinant Human TF cell lysate Human Cell N/A
    Human TF-262H Native Human Transferrin Human Plasma N/A
    Human TF-31155TH Recombinant Human TF N/A
    Human TF-31156TH Native Human TF N/A
    Human TF-31158TH Native Human TF N/A
    Human TF-3192H Recombinant Human TF, GST-tagged E.coli GST
    Human TF-321H Native Human Transferrin Rhodamine N/A
    Human TF-323H Native Human Transferrin Fluorescein N/A
    Human TF-324H Native Human Transferrin, Texas Red Label N/A
    Human TF-338HI Immobilized Human TF protein Human N/A
    Human TF-391H Native Human Transferrin Human plasma N/A
    Human TF-461H Recombinant Human Transferrin HEK293 N/A
    Human TF-4653H Recombinant Human TF protein Oryza Sativa N/A
    Human TF-4777H Human Transferrin Human Plasma N/A
    Human TF-4778H Human Transferrin Human Plasma N/A
    Human TF-5341H Native Human Transferring Human Plasma N/A
    Human TF-543HG GMP Recombinant Human TF protein(Not iron-free), Fc-tagged HEK293 Fc
    Human TF-544HG GMP Recombinant Human TF protein(iron-free), Fc-tagged HEK293 Fc
    Human TF-62H Recombinant Human Apo Transferrin (ATF) N/A
    Human TF-651H Recombinant Human TF Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human TF-8271H Native Human Serum Transferrin APO (Iron Free) Human Serum N/A
    Human TF-8273H Native Human Serum Transferrin HOLO(iron-saturated) Human Serum N/A
    Mouse TF-1208MCL Recombinant Mouse TF cell lysate Human Cell N/A
    Mouse TF-379M Recombinant Mouse TF protein, Mouse IgG2a Fc-tagged, low endotoxin HEK293 Mouse/IgG2a/Fc
    Mouse TRF-17328M Recombinant Mouse TRF Protein Mammalian Cell His
    Mouse Trf-4782M Native Mouse Transferrin Mouse Serum N/A
    Mouse Trf-58M Mouse Transferrin Reference Standard N/A
    Mouse Trf-70M Native Mouse Apotransferrin Mouse Plasma N/A
    Mouse Trf-8682M Recombinant Mouse Trf, Fc tagged Human Cell N/A
    Mouse Trf-8683M Recombinant Mouse Trf, His tagged Human Cell GST
    Rat TF-001RCL Recombinant Rat TF cell lysate Human Cell N/A
    Rat Tf-151R Recombinant Rat Tf Protein, His-tagged E.coli His
    Rat Tf-264R Native Rat Transferrin rat plasma N/A
    Rat Tf-392R Native Rat Transferrin Rat N/A
    Rat Tf-4816R Rat Transferrin N/A
    Rat Tf-566R Recombinant Rat Tf, His-tagged Human Cell His
    Rat TF-6023R Recombinant Rat TF Protein Mammalian Cell His
    Rat TF-71R Native Rat Apotransferrin Rat Plasma N/A
    Rat Tf-92R Rat Transferrin Reference Standard N/A
    Rat TF-93R Native Rat Transferrin Rat Plasma N/A
    Dog TF-25D Dog Transferrin Reference Standard N/A
    Bovine TF-132B Native Bovine Transferrin Bovine Serum N/A
    Bovine TF-146B Recombinant Bovine TF Protein, His-tagged E.coli His
    Rabbit TF -67R Rabbit Transferrin Reference Standard N/A
    Chicken TF-12C Chicken Ovotransferrin Reference Standard N/A
    Rabbit TF-135R Native Rabbit Transferrin Rabbit Skeletal Muscle N/A
    Chicken TF-136C Native Chicken Ovotransferrin Chicken Egg White N/A
    Chicken TF-143C Native Chicken Serum Transferrin Chicken Serum N/A
    Chicken TF-6856C Recombinant Chicken TF Mammalian Cell His
    Pig TF-150P Recombinant Pig TF Protein, His-tagged E.coli His
    Pig TF-1554SCL Recombinant Sus scrofa (Pig) TF cell lysate Human Cell N/A
    Sheep TF-172S Native Sheep transferrin Sheep Serum N/A
    Monkey TF-261M Native Monkey Transferrin Monkey plasma N/A
    Cattle TF-47C Native Cattle Transferrin (TRF) Protein Cattle N/A
    Pig TF-48P Native Pig Transferrin (TRF) Protein Pig N/A
    Pig TF-568P Recombinant Pig TF Protein, Fc-tagged HEK293 Fc
    Pig TF-569P Recombinant Pig TF Protein, His-tagged HEK293 His
    Gallus gallus (chicken) TF-8663C Natural Gallus gallus (chicken) transferrin (ovotransferrin) protein Conalbumin from Chicken egg white
    Kit-0813 TF (Human) Chromogenic Activity Assay Kit N/A
    TF-4203H Recombinant Human Transferrin Human N/A

    TF involved in several pathways and played different roles in them. We selected most pathways TF participated on our site, such as HIF- signaling pathway, Mineral absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with TF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    HIF- signaling pathway RPS6KB1; EIF4E1B; PFKL; RELA; PDHB; PLCG1; GAPDH; CAMK2G; HK3; RPS6
    Mineral absorption ATP1A3; CYBRD1; VDR; ATP1B3; ATP1A2; ATP1B1; MT1F; SLC11A2; TRPM6; ATP2B1

    TF has several biochemical functions, for example, ferric iron binding, ferric iron transmembrane transporter activity, ferrous iron binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TF itself. We selected most functions TF had, and list some proteins which have the same functions with TF. You can find most of the proteins on our site.

    Function Related Protein
    ferric iron binding FTH1; ACP5; TH; FTH1B; FTH1A; MIOX; Trf; FXN; TF; FTL
    ferric iron transmembrane transporter activity Trf; TF
    ferrous iron binding CDO1; Trf; ISCU; ALKBH1; FXN; ALKBH2; NT5E; ALKBH3; DNAJC24; TET2
    protein binding ARF6; RAD51D; LHFPL5; GTPBP2; SAFB; RLN3; TRAF2; MR1; PROM1; PSMA7
    transferrin receptor binding TF; SNX4; SNX2; Trf; HFE2; HFE; RGMA; SNX1; CD81

    TF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TF here. Most of them are supplied by our site. Hope this information will be useful for your research of TF.

    GAST; ESR1; TFRC; GTF2F2; MIS12; Akap12; TUBB4A; GRB2; SH3BP2; SMAD3; q99ib8-pro_0000045599; TIMELESS; LAMC3; PTBP3

    Zhu, SJ; Kisiel, W; et al. Visualizing cancer and response to therapy in vivo using Cy5.5-labeled factor VIIa and anti-tissue factor antibody. JOURNAL OF DRUG TARGETING 23:257-265(2015).
    Paoletti, F; Malerba, F; et al. A comparative analysis of the structural, functional and biological differences between Mouse and Human Nerve Growth Factor. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS 1854:187-197(2015).


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