TF Protein


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Official Full Name transferrin
Background This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009] Transferrin is a metal-combining protein that reversibly bound to acid-soluble iron in plasma. It functions to transport iron to the bone marrow and to tissue storage organs such as the liver. Transferrin also participate in the regulation and control of iron absorption and protects against iron intoxication. Like haptoglobin, the carrier of hemoglobin, transferrin is synthesized in the liver, but unlike haptoglobin transferrin is returned to the circulation after unloading its iron in the reticuloendothelial system. This ELISA kit can be used to measure transferrin in serum, tissue extracts and other biological fluids.
Synonyms TF; transferrin; TFQTL1; PRO1557; PRO2086; serotransferrin; siderophilin; beta-1 metal-binding globulin; AI266983; Cd176; HP; Tfn; hpx; hypotransferrinemia with hemochromatosis; Apotransferrin; Beta 1 metal binding globulin; DKFZp781D0156; PRO1400; Serotransferrin precursor; Transferin; TRFE_HUMAN;
    • Species :
    • Bovine
    • Cattle
    • Chicken
    • Dog
    • Gallus gallus (chicken)
    • Human
    • Monkey
    • Mouse
    • Pig
    • Rabbit
    • Rat
    • Sheep
    • Source :
    • Bovine Serum
    • Cattle
    • Chicken Egg White
    • Chicken Serum
    • CHO-K1
    • Conalbumin from Chicken egg white
    • E.coli
    • HEK293
    • Human
    • Human Cell
    • Human Plasma
    • Human Serum
    • Mammalian Cell
    • Mammalian cells
    • Monkey plasma
    • Mouse Plasma
    • Mouse Serum
    • Oryza Sativa
    • Pig
    • Rabbit Skeletal Muscle
    • Rat
    • Rat Plasma
    • Serum
    • Sheep Serum
    • Yeast
    • Tag :
    • Fc
    • Flag
    • GST
    • His
    • His (Fc)-Avi
    • His-KSI
    • Mouse
    • IgG2a
    • Myc
    • DDK
    • N/A
    • N-His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TF-461H Active Recombinant Human Transferrin HEK293 N/A Inquiry
    Human TF-4653H Active Recombinant Human TF protein Oryza Sativa N/A Inquiry
    Pig TF-568P Active Recombinant Pig TF Protein, Fc-tagged HEK293 Fc Inquiry
    Pig TF-569P Active Recombinant Pig TF Protein, His-tagged HEK293 His Inquiry
    Human TF-03H Recombinant Human Transferrin Oryza Sativa N/A Inquiry
    Human TF-056H Recombinant Human TF Protein, His-tagged HEK293 His Inquiry
    Human TF-2351H Recombinant Human TF, His tagged Human Cell His Inquiry
    Human TF-31155TH Recombinant Human TF N/A Inquiry
    Human TF-3192H Recombinant Human TF, GST-tagged E.coli GST Inquiry
    Human TF-4777H Human Transferrin Human Plasma N/A Inquiry
    Human TF-4778H Human Transferrin Human Plasma N/A Inquiry
    Human TF-62H Recombinant Human Apo Transferrin (ATF) N/A Inquiry
    Mouse TRF-17328M Recombinant Mouse TRF Protein Mammalian Cell His Inquiry
    Mouse Trf-8682M Recombinant Mouse Trf, Fc tagged Human Cell N/A Inquiry
    Mouse Trf-8683M Recombinant Mouse Trf, His tagged Human Cell GST Inquiry
    Rat Tf-4816R Rat Transferrin N/A Inquiry
    Rat Tf-566R Recombinant Rat Tf, His-tagged Human Cell His Inquiry
    Rat TF-6023R Recombinant Rat TF Protein Mammalian Cell His Inquiry
    Chicken TF-6856C Recombinant Chicken TF Mammalian Cell His Inquiry
    TF-4203H Recombinant Human Transferrin Human N/A Inquiry
    Human TF-2542HCL Recombinant Human TF cell lysate Human Cell N/A Inquiry
    Mouse TF-1208MCL Recombinant Mouse TF cell lysate Human Cell N/A Inquiry
    Rat TF-001RCL Recombinant Rat TF cell lysate Human Cell N/A Inquiry
    Pig TF-1554SCL Recombinant Sus scrofa (Pig) TF cell lysate Human Cell N/A Inquiry
    Bovine TF-01B Native Bovine TF Protein Inquiry
    Cattle TF-01HG GMP Native Cattle TF Protein Inquiry
    Human TF-2175H Recombinant Human TF Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi Inquiry
    Chicken TF-2760C Recombinant Chicken TF Protein, His-tagged E.coli N-His Inquiry
    Rat Tf-3563R Recombinant Rat Tf protein, His-KSI-tagged E.coli His-KSI Inquiry
    Human TF-393HFL Recombinant Full Length Human TF Protein, C-Flag-tagged Mammalian cells Flag Inquiry
    Human TF-462H Recombinant Human TF Protein, Animal Free CHO-K1 Inquiry
    Human TF-551H Recombinant Human TF Protein, His-tagged HEK293 His Inquiry
    Rat Tf-5526R Recombinant Rat Tf protein, His-tagged Yeast His Inquiry
    Rat TF-5682R Recombinant Rat TF Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi Inquiry
    Mouse TF-9147M Recombinant Mouse TF Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi Inquiry
    Human TF-001H Recombinant Human TF Protein Oryza Sativa Inquiry
    Human TF-002H Native Human TF Protein, Rhodamine Conjugated Serum N/A Inquiry
    Human TF-102H Native Human Transferrin (HOLO) Human Plasma N/A Inquiry
    Human TF-103H Native Human Apotransferrin Human Plasma N/A Inquiry
    Human TF-147H Recombinant Human TF Protein, His-tagged E.coli His Inquiry
    Human TF-24H Human Transferrin Reference Standard N/A Inquiry
    Human TF-262H Native Human Transferrin Human Plasma N/A Inquiry
    Human TF-31156TH Native Human TF N/A Inquiry
    Human TF-31158TH Native Human TF N/A Inquiry
    Human TF-321H Native Human Transferrin Rhodamine N/A Inquiry
    Human TF-323H Native Human Transferrin Fluorescein N/A Inquiry
    Human TF-324H Native Human Transferrin, Texas Red Label N/A Inquiry
    Human TF-338HI Immobilized Human TF protein Human N/A Inquiry
    Human TF-391H Native Human Transferrin Human plasma N/A Inquiry
    Human TF-5341H Native Human Transferring Human Plasma N/A Inquiry
    Human TF-543HG GMP Recombinant Human TF protein(Not iron-free), Fc-tagged HEK293 Fc Inquiry
    Human TF-544HG GMP Recombinant Human TF protein(iron-free), Fc-tagged HEK293 Fc Inquiry
    Human TF-651H Recombinant Human TF Protein, MYC/DDK-tagged HEK293 Myc/DDK Inquiry
    Human TF-8271H Native Human Serum Transferrin APO (Iron Free) Human Serum N/A Inquiry
    Human TF-8273H Native Human Serum Transferrin HOLO(iron-saturated) Human Serum N/A Inquiry
    Mouse TF-379M Recombinant Mouse TF protein, Mouse IgG2a Fc-tagged, low endotoxin HEK293 Mouse/IgG2a/Fc Inquiry
    Mouse Trf-148M Recombinant Mouse Trf Protein, His-tagged E.coli His Inquiry
    Mouse Trf-4782M Native Mouse Transferrin Mouse Serum N/A Inquiry
    Mouse Trf-58M Mouse Transferrin Reference Standard N/A Inquiry
    Mouse Trf-70M Native Mouse Apotransferrin Mouse Plasma N/A Inquiry
    Rat Tf-151R Recombinant Rat Tf Protein, His-tagged E.coli His Inquiry
    Rat Tf-264R Native Rat Transferrin rat plasma N/A Inquiry
    Rat Tf-392R Native Rat Transferrin Rat N/A Inquiry
    Rat TF-71R Native Rat Apotransferrin Rat Plasma N/A Inquiry
    Rat Tf-92R Rat Transferrin Reference Standard N/A Inquiry
    Rat TF-93R Native Rat Transferrin Rat Plasma N/A Inquiry
    Dog TF-25D Dog Transferrin Reference Standard N/A Inquiry
    Bovine TF-132B Native Bovine Transferrin Bovine Serum N/A Inquiry
    Bovine TF-146B Recombinant Bovine TF Protein, His-tagged E.coli His Inquiry
    Rabbit TF -67R Rabbit Transferrin Reference Standard N/A Inquiry
    Chicken TF-12C Chicken Ovotransferrin Reference Standard N/A Inquiry
    Rabbit TF-135R Native Rabbit Transferrin Rabbit Skeletal Muscle N/A Inquiry
    Chicken TF-136C Native Chicken Ovotransferrin Chicken Egg White N/A Inquiry
    Chicken TF-143C Native Chicken Serum Transferrin Chicken Serum N/A Inquiry
    Pig TF-150P Recombinant Pig TF Protein, His-tagged E.coli His Inquiry
    Sheep TF-172S Native Sheep transferrin Sheep Serum N/A Inquiry
    Monkey TF-261M Native Monkey Transferrin Monkey plasma N/A Inquiry
    Cattle TF-47C Native Cattle Transferrin (TRF) Protein Cattle N/A Inquiry
    Pig TF-48P Native Pig Transferrin (TRF) Protein Pig N/A Inquiry
    Gallus gallus (chicken) TF-8663C Natural Gallus gallus (chicken) transferrin (ovotransferrin) protein Conalbumin from Chicken egg white Inquiry
    Kit-0813 TF (Human) Chromogenic Activity Assay Kit N/A Inquiry

    TF involved in several pathways and played different roles in them. We selected most pathways TF participated on our site, such as HIF- signaling pathway, Mineral absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with TF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    HIF- signaling pathway ANGPT2; HK3; CAMK2B; IFNGR1; PIK3R1; INS; MAPK1; BCL2; INS2; IL6
    Mineral absorption VDR; CLCN2; MT2A; STEAP2; MT1H; SLC26A3; SLC31A1; SLC34A2; ATP1B4; SLC9A3

    TF has several biochemical functions, for example, ferric iron binding, ferric iron transmembrane transporter activity, ferrous iron binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TF itself. We selected most functions TF had, and list some proteins which have the same functions with TF. You can find most of the proteins on our site.

    Function Related Protein
    ferric iron binding FTH1A; FTL; TF; FXN; FTH1B; Trf; TH; FTMT; ACP5; FTHL17
    ferric iron transmembrane transporter activity Trf; TF
    ferrous iron binding CDO1; ISCU; FTO; ISCA1; UROD; FECH; TH; FXN; DNAJC24; PLOD1
    protein binding DEFB121; GPI1; NUDT10; SNX5; TRIM21; TRIM42; CRYBB1; KHDC3; BECN1; CORO6
    transferrin receptor binding SNX2; HFE2; TF; SNX1; SNX4; CD81; HFE; RGMA; Trf

    TF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TF here. Most of them are supplied by our site. Hope this information will be useful for your research of TF.

    GAST; ESR1; TFRC; GTF2F2; MIS12; Akap12; TUBB4A; GRB2; SH3BP2; SMAD3; q99ib8-pro_0000045599; TIMELESS; LAMC3; PTBP3

    Zhu, SJ; Kisiel, W; et al. Visualizing cancer and response to therapy in vivo using Cy5.5-labeled factor VIIa and anti-tissue factor antibody. JOURNAL OF DRUG TARGETING 23:257-265(2015).
    Paoletti, F; Malerba, F; et al. A comparative analysis of the structural, functional and biological differences between Mouse and Human Nerve Growth Factor. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS 1854:187-197(2015).

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