tf
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  • Official Full Name
  • transferrin
  • Background
  • This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009] Transferrin is a metal-combining protein that reversibly bound to acid-soluble iron in plasma. It functions to transport iron to the bone marrow and to tissue storage organs such as the liver. Transferrin also participate in the regulation and control of iron absorption and protects against iron intoxication. Like haptoglobin, the carrier of hemoglobin, transferrin is synthesized in the liver, but unlike haptoglobin transferrin is returned to the circulation after unloading its iron in the reticuloendothelial system. This ELISA kit can be used to measure transferrin in serum, tissue extracts and other biological fluids.
  • Synonyms
  • TF; transferrin; TFQTL1; PRO1557; PRO2086; serotransferrin; siderophilin; beta-1 metal-binding globulin; AI266983; Cd176; HP; Tfn; hpx; hypotransferrinemia with hemochromatosis; Apotransferrin; Beta 1 metal binding globulin; DKFZp781D0156; PRO1400; Serotransferrin precursor; Transferin; TRFE_HUMAN
Cat.#:TF-379MTag:MIgG2a Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse TF Protein, MIgG2a Fc-tagged, low endotoxin
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Cat.#:TF-147HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TF Protein, His-tagged
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Cat.#:TF-651HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human TF Protein, MYC/DDK-tagged
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Cat.#:Tf-151RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Tf Protein, His-tagged
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Cat.#:TF-146BTag:His
Source (Host):E. coliSpecies:Bovine
Product nameRecombinant Bovine TF Protein, His-tagged
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Cat.#:TF-150PTag:His
Source (Host):E. coliSpecies:Pig
Product nameRecombinant Pig TF Protein, His-tagged
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Cat.#:TF-461HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human Transferrin
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Cat.#:TF -62HTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human Apo Transferrin (ATF)
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Cat.#:TF-056HTag:His
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human TF Protein, His-tagged
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Cat.#:TF-2351HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human TF, His tagged
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Cat.#:TF-31155THTag:
Source (Host):Species:Human
Product nameRecombinant Human TF
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Cat.#:TF-3192HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TF, GST-tagged
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Cat.#:TF-4653HTag:
Source (Host):Oryza sativaSpecies:Human
Product nameRecombinant Human TF protein
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Cat.#:TF-4777HTag:N/A
Source (Host):Human plasmaSpecies:Human
Product nameHuman Transferrin
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Cat.#:TF-4778HTag:N/A
Source (Host):Human plasmaSpecies:Human
Product nameHuman Transferrin
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Cat.#:TRF-17328MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TRF Protein
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Cat.#:Trf-8682MTag:N/A
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Trf, Fc tagged
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Cat.#:Trf-8683MTag:GST
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Trf, His tagged
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Cat.#:Tf-4816RTag:N/A
Source (Host):Species:Rat
Product nameRat Transferrin
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Cat.#:Tf-566RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Tf, His-tagged
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Cat.#:TF-6023RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat TF Protein
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Cat.#:TF-6856CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken TF
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Cat.#:TF-568PTag:Fc
Source (Host):HEK293Species:Pig
Product nameRecombinant Pig TF Protein, Fc-tagged
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Cat.#:TF-569PTag:His
Source (Host):HEK293Species:Pig
Product nameRecombinant Pig TF Protein, His-tagged
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Cat.#:TF-4203HTag:N/A
Source (Host):Species:
Product nameRecombinant Human Transferrin
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Cat.#:TF-03HTag:
Source (Host):RiceSpecies:Human
Product nameRecombinant Human Transferrin
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Cat.#:TF-002HTag:
Source (Host):SerumSpecies:Human
Product nameNative Human TF Protein, Rhodamine Conjugated
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Cat.#:TF-102HTag:N/A
Source (Host):Human plasmaSpecies:Human
Product nameNative Human Transferrin (HOLO)
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Cat.#:TF-103HTag:N/A
Source (Host):Human plasmaSpecies:Human
Product nameNative Human Apotransferrin
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Cat.#:TF-262HTag:
Source (Host):Species:Human
Product nameNative Human Transferrin
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Cat.#:TF-31156THTag:
Source (Host):Species:Human
Product nameNative Human TF
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Cat.#:TF-31158THTag:
Source (Host):Species:Human
Product nameNative Human TF
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Cat.#:TF-321HTag:
Source (Host):Species:Human
Product nameNative Human Transferrin Rhodamine
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Cat.#:TF-323HTag:
Source (Host):Species:Human
Product nameNative Human Transferrin Fluorescein
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Cat.#:TF-324HTag:
Source (Host):Species:Human
Product nameNative Human Transferrin, Texas Red Label
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Cat.#:TF-391HTag:N/A
Source (Host):Human plasmaSpecies:Human
Product nameNative Human Transferrin
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Cat.#:TF-5341HTag:N/A
Source (Host):Human plasmaSpecies:Human
Product nameNative Human Transferring
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Cat.#:TF-8271HTag:N/A
Source (Host):Human SerumSpecies:Human
Product nameNative Human Serum Transferrin APO (Iron Free)
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Cat.#:TF-8273HTag:N/A
Source (Host):Human SerumSpecies:Human
Product nameNative Human Serum Transferrin HOLO(iron-saturated)
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Cat.#:Trf-4782MTag:N/A
Source (Host):Mouse SerumSpecies:Mouse
Product nameNative Mouse Transferrin
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Cat.#:Trf-70MTag:
Source (Host):Species:Mouse
Product nameNative Mouse Apotransferrin
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Cat.#:Tf-264RTag:
Source (Host):Species:Rat
Product nameNative Rat Transferrin
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Cat.#:Tf-392RTag:N/A
Source (Host):RatSpecies:Rat
Product nameNative Rat Transferrin
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Cat.#:TF-71RTag:
Source (Host):Species:Rat
Product nameNative Rat Apotransferrin
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Cat.#:TF-93RTag:
Source (Host):Species:Rat
Product nameNative Rat Transferrin
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Cat.#:TF-132BTag:
Source (Host):Species:Bovine
Product nameNative Bovine Transferrin
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Cat.#:TF-135RTag:
Source (Host):Species:Rabbit
Product nameNative Rabbit Transferrin
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Cat.#:TF-136CTag:
Source (Host):Species:Chicken
Product nameNative Chicken Ovotransferrin
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Cat.#:TF-143CTag:
Source (Host):Species:Chicken
Product nameNative Chicken Serum Transferrin
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Cat.#:TF-172STag:
Source (Host):Species:Sheep
Product nameNative Sheep transferrin
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Cat.#:TF-261MTag:
Source (Host):Species:Monkey
Product nameNative Monkey Transferrin
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Cat.#:TF-47CTag:
Source (Host):CattleSpecies:Cattle
Product nameNative Cattle Transferrin (TRF) Protein
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Cat.#:TF-48PTag:
Source (Host):PigSpecies:Pig
Product nameNative Pig Transferrin (TRF) Protein
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Cat.#:TF-2542HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human TF cell lysate
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Cat.#:TF-1208MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse TF cell lysate
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Cat.#:TF-001RCLTag:
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat TF cell lysate
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Cat.#:TF-1554SCLTag:
Source (Host):HEK293Species:Pig
Product nameRecombinant Sus scrofa (Pig) TF cell lysate
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Cat.#:Kit-0813Tag:
Source (Host):Species:
Product nameTF (Human) Chromogenic Activity Assay Kit
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Cat.#:TF-24HTag:
Source (Host):Species:Human
Product nameHuman Transferrin Reference Standard
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Cat.#:Trf-58MTag:N/A
Source (Host):Species:Mouse
Product nameMouse Transferrin Reference Standard
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Cat.#:Tf-92RTag:N/A
Source (Host):Species:Rat
Product nameRat Transferrin Reference Standard
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Cat.#:TF-25DTag:N/A
Source (Host):Species:Dog
Product nameDog Transferrin Reference Standard
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Cat.#:TF -67RTag:N/A
Source (Host):Species:Rabbit
Product nameRabbit Transferrin Reference Standard
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Cat.#:TF-12CTag:N/A
Source (Host):Species:Chicken
Product nameChicken Ovotransferrin Reference Standard
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Cat.#:TF-338HITag:
Source (Host):HumanSpecies:Human
Product nameImmobilized Human TF protein
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Involved Pathway

TF involved in several pathways and played different roles in them. We selected most pathways TF participated on our site, such as HIF- signaling pathway, Mineral absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with TF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
HIF- signaling pathway
RBX1; PIK3CB; HMOX1; PFKFB3; IFNGR1; MTOR; TCEB2; ERBB2; GAPDH; NFKB1
Mineral absorption
MT2; ATP1B2; SLC11A1; S100G; ATP1B1; ATP1B3; HMOX1; STEAP2; SLC9A3; MT1B

Protein Function

TF has several biochemical functions, for example, ferric iron binding, ferric iron transmembrane transporter activity, ferrous iron binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TF itself. We selected most functions TF had, and list some proteins which have the same functions with TF. You can find most of the proteins on our site.
Function
Related Protein
Function ferric iron binding
Related Protein FTH1B; Trf; MIOX; TH; FXN; ACP5; TF; FTMT; FTH1; FTHL17
Function ferric iron transmembrane transporter activity
Related Protein TF; Trf
Function ferrous iron binding
Related Protein HEPH; TRR1; EGLN2; TET2; UROD; SERPINB1A; CDO1; FXN; ISCA1; HAAO
Function protein binding
Related Protein MINOS1; ATPAF1; GALR2; MEF2D; C17orf28; PPP1R12B; EHD2; THRAP3; NLGN4X; BIN3
Function transferrin receptor binding
Related Protein SNX4; HFE; SNX1; TF; CD81; HFE2; SNX2; RGMA; Trf

Interacting Protein

TF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TF here. Most of them are supplied by our site. Hope this information will be useful for your research of TF.
GAST; ESR1; TFRC; GTF2F2; MIS12; Akap12; TUBB4A; GRB2; SH3BP2; SMAD3; q99ib8-pro_0000045599; TIMELESS; LAMC3; PTBP3

TF Related Articles

Zhu, SJ; Kisiel, W; et al. Visualizing cancer and response to therapy in vivo using Cy5.5-labeled factor VIIa and anti-tissue factor antibody. JOURNAL OF DRUG TARGETING 23:257-265(2015).
Paoletti, F; Malerba, F; et al. A comparative analysis of the structural, functional and biological differences between Mouse and Human Nerve Growth Factor. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS 1854:187-197(2015).

TF Related Gene Family

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