TF

  • Official Full Name

    transferrin

  • Overview

    This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009] Transferrin is a metal-combining protein that reversibly bound to acid-soluble iron in plasma. It functions to transport iron to the bone marrow and to tissue storage organs such as the liver. Transferrin also participate in the regulation and control of iron absorption and protects against iron intoxication. Like haptoglobin, the carrier of hemoglobin, transferrin is synthesized in the liver, but unlike haptoglobin transferrin is returned to the circulation after unloading its iron in the reticuloendothelial system. This ELISA kit can be used to measure transferrin in serum, tissue extracts and other biological fluids.
  • Synonyms

    TF; transferrin; TFQTL1; PRO1557; PRO2086; serotransferrin; siderophilin; beta-1 metal-binding globulin; AI266983; Cd176; HP; Tfn; hpx; hypotransferrinemia with hemochromatosis; Apotransferrin; Beta 1 metal binding globulin; DKFZp781D0156; PRO1400; Serotransferrin precursor; Transferin; TRFE_HUMAN;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Transfected Stable Cell Lines
  • Native Proteins
  • GMP Proteins
  • Others
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Bovine
  • Cattle
  • Chicken
  • Dog
  • Gallus gallus (chicken)
  • Human
  • Monkey
  • Mouse
  • Pig
  • Rabbit
  • Rat
  • Sheep
  • Bovine Serum
  • Cattle
  • Chicken Egg White
  • Chicken Serum
  • CHO-K1
  • Conalbumin from Chicken egg white
  • E.coli
  • HEK293
  • Human
  • Human Cell
  • Human plasma
  • Human Plasma
  • Human Serum
  • Mammalian Cell
  • Mammalian cells
  • Monkey plasma
  • Mouse Plasma
  • Mouse Serum
  • Oryza Sativa
  • Pichia pastoris
  • Pig
  • Rabbit Skeletal Muscle
  • Rat
  • rat plasma
  • Rat Plasma
  • Serum
  • Sheep Serum
  • Yeast
  • C
  • hFc
  • His
  • Fc
  • Flag
  • GST
  • His (Fc)
  • Avi
  • KSI
  • mFc
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TF-461H Active Recombinant Human Transferrin HEK293 N/A
Human TF-4653H Active Recombinant Human TF protein Oryza Sativa N/A
Human TF-31155TH Recombinant Human TF N/A
Human TF-4777H Human Transferrin Human Plasma N/A
Human TF-3192H Recombinant Human TF, GST-tagged E.coli GST 347-698aa
Human TF-03H Recombinant Human Transferrin Oryza Sativa N/A
Human TF-056H Active Recombinant Human TF protein, His-tagged HEK293 His Val 20 - Pro 698
Human TF-4778H Human Transferrin Human Plasma N/A
Human TF-62H Recombinant Human Apo Transferrin (ATF) N/A
Human TF-2351H Recombinant Human TF, His tagged Human Cell His
Human TF-2542HCL Recombinant Human TF cell lysate Human Cell N/A
Human TF-24H Active Human Transferrin Reference Standard N/A
Human TF-262H Native Human Transferrin Human Plasma N/A
Human TF-391H Native Human Transferrin Human plasma N/A
Human TF-8271H Native Human Serum Transferrin APO (Iron Free) Human Serum N/A
Human TF-103H Native Human Apotransferrin Human Plasma N/A
Human TF-102H Native Human Transferrin (HOLO) Human Plasma N/A
Human TF-544HG Active GMP Recombinant Human TF protein(iron-free), Fc-tagged HEK293 Fc DNA sequence encoding Human Transferrin(Q06AH7) was expressed with Fc tag at the C-terminal.
Human TF-8273H Native Human Serum Transferrin HOLO(iron-saturated) Human Serum N/A
Human TF-323H Native Human Transferrin Fluorescein N/A
Human TF-5341H Native Human Transferring Human Plasma N/A
Human TF-338HI Immobilized Human TF protein Human N/A
Human TF-31156TH Native Human TF N/A
Human TF-321H Native Human Transferrin Rhodamine N/A
Human TF-462H Recombinant Human TF Protein, Animal Free CHO-K1
Human TF-147H Recombinant Human TF Protein, His-tagged E.coli His Val361~Lys683
Human TF-31158TH Native Human TF N/A
Human TF-324H Native Human Transferrin, Texas Red Label N/A
Human TF-11H Recombinant Human Apo-Transferrin, Low Endotoxin, Media Grade Pichia pastoris N/A
Human TF-651H Recombinant Human TF Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human TF-001H Active Recombinant Human TF Protein Oryza Sativa
Human TF-543HG Active GMP Recombinant Human TF protein(Not iron-free), Fc-tagged HEK293 Fc DNA sequence encoding Human Transferrin(Q06AH7) was expressed with Fc tag at the C-terminal.
Human TF-393HFL Recombinant Full Length Human TF Protein, C-Flag-tagged Mammalian cells Flag
Human TF-002H Native Human TF Protein, Rhodamine Conjugated Serum N/A
Human TF-2175H-B Recombinant Human TF Protein Pre-coupled Magnetic Beads HEK293
Human TF-551H Recombinant Human TF Protein, His-tagged HEK293 His
Human TF-2175H Recombinant Human TF Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human TF-10H Recombinant Human Holo-Transferrin, Low Endotoxin, Media Grade Pichia pastoris N/A
Mouse TF-379M Active Recombinant Mouse TF protein, mFc-tagged HEK293 mFc Val 20 - His 697
Mouse Trf-8682M Recombinant Mouse Trf, Fc tagged Human Cell N/A
Mouse Trf-8683M Recombinant Mouse Trf, His tagged Human Cell GST
Mouse TF-1208MCL Recombinant Mouse TF cell lysate Human Cell N/A
Mouse Trf-148M Recombinant Mouse Trf Protein, His-tagged E.coli His Val360~Lys682
Mouse Trf-4782M Native Mouse Transferrin Mouse Serum N/A
Mouse TF-9147M-B Recombinant Mouse TF Protein Pre-coupled Magnetic Beads HEK293
Mouse TF-9147M Recombinant Mouse TF Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Trf-70M Native Mouse Apotransferrin Mouse Plasma N/A
Mouse Trf-58M Mouse Transferrin Reference Standard N/A
Rat Tf-4816R Rat Transferrin N/A
Rat Tf-566R Active Recombinant Rat Tf protein(Met1-Ser698), His-tagged HEK293 C-His Met1-Ser698
Rat TF-6023R Recombinant Rat TF Protein Mammalian Cell His
Rat TF-001RCL Recombinant Rat TF cell lysate Human Cell N/A
Rat TF-5682R-B Recombinant Rat TF Protein Pre-coupled Magnetic Beads HEK293
Rat TF-5682R Recombinant Rat TF Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Tf-5526R Recombinant Rat Tf protein, His-tagged Yeast His 20-698aa
Rat Tf-92R Rat Transferrin Reference Standard N/A
Rat TF-71R Native Rat Apotransferrin Rat Plasma N/A
Rat Tf-3563R Recombinant Rat Tf protein, His-KSI-tagged E.coli His-KSI 20-698aa
Rat Tf-392R Native Rat Transferrin Rat N/A
Rat TF-93R Native Rat Transferrin Rat Plasma N/A
Rat Tf-264R Native Rat Transferrin rat plasma N/A
Rat Tf-151R Recombinant Rat Tf Protein, His-tagged E.coli His Val360~Lys683
Monkey TF-261M Native Monkey Transferrin Monkey plasma N/A
Rabbit TF-135R Native Rabbit Transferrin Rabbit Skeletal Muscle N/A Full length native Rabbit Transferrin
Rabbit TF -67R Rabbit Transferrin Reference Standard N/A
Dog TF-25D Dog Transferrin Reference Standard N/A
Bovine TF-146B Recombinant Bovine TF Protein, His-tagged E.coli His Asp284~Ala575
Bovine TF-01B Native Bovine TF Protein
Bovine TF-132B Native Bovine Transferrin Bovine Serum N/A Full length native Bovine Transferrin
Cattle TF-01HG GMP Native Cattle TF Protein
Cattle TF-47C Native Cattle Transferrin (TRF) Protein Cattle N/A
Gallus gallus (chicken) TF-8663C Natural Gallus gallus (chicken) transferrin (ovotransferrin) protein Conalbumin from Chicken egg white
Sheep TF-172S Native Sheep transferrin Sheep Serum N/A Full length native Sheep transferrin
Pig TF-568P Active Recombinant Pig TF protein(Met1-Thr715), hFc-tagged HEK293 C-hFc Met1-Thr715
Pig TF-569P Active Recombinant Pig TF Protein, His-tagged HEK293 His
Pig TF-1554SCL Recombinant Sus scrofa (Pig) TF cell lysate Human Cell N/A
Pig TF-150P Recombinant Pig TF Protein, His-tagged E.coli His Tyr318~Lys453
Pig TF-48P Native Pig Transferrin (TRF) Protein Pig N/A
Chicken TF-6856C Recombinant Chicken TF Mammalian Cell His
Chicken TF-2760C Recombinant Chicken TF Protein, His-tagged E.coli N-His Ile26-Lys352
Chicken TF-12C Chicken Ovotransferrin Reference Standard N/A
Chicken TF-136C Native Chicken Ovotransferrin Chicken Egg White N/A Full length native Chicken Ovotransferrin
Chicken TF-143C Native Chicken Serum Transferrin Chicken Serum N/A Full length native Chicken Serum Transferrin
TF-4203H Recombinant Human Transferrin Human N/A
Kit-0813 TF (Human) Chromogenic Activity Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

TF involved in several pathways and played different roles in them. We selected most pathways TF participated on our site, such as HIF- signaling pathway, Mineral absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with TF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
HIF- signaling pathwayPIK3R2;TF;ENO2;INS2;EP300;PLCG1;IFNGR1;PIK3CD;ERBB2
Mineral absorptionATP1A1;SLC31A1;ATP1B1;HEPH;Trf;MT1;ATP1A2;FXYD2;ATP1A4

TF has several biochemical functions, for example, ferric iron binding, ferric iron transmembrane transporter activity, ferrous iron binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TF itself. We selected most functions TF had, and list some proteins which have the same functions with TF. You can find most of the proteins on our site.

Function Related Protein
ferric iron bindingACP5;MIOX;FTH1B;Trf;FTL;TF;FTH1A;TH;FTH1
ferric iron transmembrane transporter activityTF;Trf
ferrous iron bindingBCO1;FTO;ISCU;ALKBH3;FXN;FECH;NT5E;ALKBH1;PLOD1
protein bindingPPP1R2P3;JAKMIP1;P2RX7;NDEL1;BARHL2;ANKS1A;FNDC3B;RAPGEF6;CDC42EP4
transferrin receptor bindingHFE;SNX1;SNX2;Trf;TF;SNX4;CD81;HFE2;RGMA

TF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TF here. Most of them are supplied by our site. Hope this information will be useful for your research of TF.

GAST; ESR1; TFRC; GTF2F2; MIS12; Akap12; TUBB4A; GRB2; SH3BP2; SMAD3; q99ib8-pro_0000045599; TIMELESS; LAMC3; PTBP3

Gene Family

IL

Research Area

Related articles

Zhu, SJ; Kisiel, W; et al. Visualizing cancer and response to therapy in vivo using Cy5.5-labeled factor VIIa and anti-tissue factor antibody. JOURNAL OF DRUG TARGETING 23:257-265(2015).
Paoletti, F; Malerba, F; et al. A comparative analysis of the structural, functional and biological differences between Mouse and Human Nerve Growth Factor. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS 1854:187-197(2015).
  • Reviews
  • Q&As

Customer Reviews (3)

Write a review
Reviews
08/01/2020

    Their team of experts is not only knowledgeable about the TF protein but is also dedicated to assisting researchers like myself in overcoming any challenges that may arise.

    01/22/2018

      This high-quality protein is crucial for the success of my experiments, ensuring that I obtain reliable and meaningful scientific findings.

      04/11/2016

        The TF protein is of exceptional quality, making it a perfect fit for my experimental needs.

        Q&As (5)

        Ask a question
        Can TF proteins be used for diagnosing diseases? 03/19/2021

        Yes, abnormalities in TF proteins can serve as diagnostic markers for certain diseases.

        Are there any approved drugs that target TF proteins? 11/27/2020

        Yes, some drugs target TF proteins, especially in the treatment of cancer.

        How do TF proteins contribute to autoimmune diseases? 08/25/2020

        TF proteins can trigger or suppress immune responses, making them relevant in understanding autoimmune diseases.

        How do TF proteins play a crucial role in clinical applications? 03/16/2016

        TF proteins are vital for understanding disease mechanisms and can be targeted for therapeutic purposes.

        Are there any clinical tests or assays that measure TF protein levels? 03/05/2016

        Yes, various assays, like ELISA and Western blot, can be used to quantify TF protein levels.

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