Native Human Apotransferrin

• Cat.No.: TF-103H
• Product Overview: Native Human Apotransferrin was purified from Human Plasma.

Specification

• Description: This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum.
• Source: Human Plasma
• Species: Human
• Form: Lyophilized from 10 mM phosphate buffer, pH 7.4.
• Molecular Mass: 80 kDa
• Purity: ≥95% by SDS-PAGE
• Quality Control Test: Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
• Storage: Store at -20°C.
• Tag: Non

Gene Information

• Gene Name: TF transferrin [ Homo sapiens ]
• Official Symbol: TF
• Synonyms: TF; transferrin; serotransferrin; PRO1557; PRO2086; siderophilin; beta-1 metal-binding globulin; TFQTL1; DKFZp781D0156
• Gene ID: 7018
• mRNA Refseq: NM_001063
• Protein Refseq: NP_001054
• MIM: 190000
• UniProt ID: P02787
• Chromosome Location: 3q21
• Pathway: EPHB forward signaling, organism-specific biosystem; HIF-1-alpha transcription factor network, organism-specific biosystem; Hemostasis, organism-specific biosystem; Iron uptake and transport, organism-specific biosystem; Mineral absorption, organism-specific biosystem; Mineral absorption, conserved biosystem; Platelet activation, signaling and aggregation, organism-specific biosystem
• Function: ferric iron binding; metal ion binding; protein binding; ubiquitin protein ligase binding

Reviews

08/01/2020

Their team of experts is not only knowledgeable about the TF protein but is also dedicated to assisting researchers like myself in overcoming any challenges that may arise.

01/22/2018

This high-quality protein is crucial for the success of my experiments, ensuring that I obtain reliable and meaningful scientific findings.

04/11/2016

The TF protein is of exceptional quality, making it a perfect fit for my experimental needs.

Q&As

Can TF proteins be used for diagnosing diseases?

Yes, abnormalities in TF proteins can serve as diagnostic markers for certain diseases.

Are there any approved drugs that target TF proteins?

Yes, some drugs target TF proteins, especially in the treatment of cancer.

How do TF proteins contribute to autoimmune diseases?

TF proteins can trigger or suppress immune responses, making them relevant in understanding autoimmune diseases.

How do TF proteins play a crucial role in clinical applications?

TF proteins are vital for understanding disease mechanisms and can be targeted for therapeutic purposes.

Are there any clinical tests or assays that measure TF protein levels?

Yes, various assays, like ELISA and Western blot, can be used to quantify TF protein levels.