Native Mouse Transferrin

• Cat.No.: Trf-4782M
• Product Overview: Native Mouse Transferrin was purified from Mouse Serum.

Specification

• Description: Mouse Transferrin is a blood plasma glycoprotein which binds iron and regulates the amount of available iron in circulation. Mouse Transferrin has a high affinity for iron, but this binding is reversible. Mouse Transferrin has a molecular weight of approximately 80kDa. Mouse Transferrin also plays a role in the immune system, creating environments low in iron for which many pathogenic bacteria are unable to thrive.
• Source: Mouse Serum
• Species: Mouse
• Form: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
• Molecular Mass: ~80 kDa
• Purity: Mouse Transferrin was prepared from normal serum by a multi-step process which includes delipidation and selective precipitation followed by extensive dialysis against the buffer stated above. Mouse Transferrin was assayed by immunoelectrophoresis resulted in a single precipitin arc against anti-Mouse Transferrin and anti-Mouse Serum.
• Applications: Mouse Transferrin is a suitable protein for use as a control reagent in SDS, Western Blotting, and ELISA experiments.
• Storage: Store vial at 4 centigrade prior to opening. For extended storage aliquot contents and freeze at -20 centigradeor below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Mouse Transferrin is stable for several weeks at 4 centigradeas an undiluted liquid. Dilute only prior to immediate use.
• Concentration: 5.9 mg/mL by UV absorbance at 280 nm
• Tag: Non

Gene Information

• Gene Name: Trf transferrin [ Mus musculus ]
• Official Symbol: Trf
• Synonyms: TRF; transferrin; serotransferrin; siderophilin; beta-1 metal-binding globulin; hypotransferrinemia with hemochromatosis; HP; Tf; Tfn; hpx; Cd176; AI266983; MGC102653
• Gene ID: 22041
• mRNA Refseq: NM_133977
• Protein Refseq: NP_598738
• UniProt ID: Q921I1
• Chromosome Location: 9 F1; 9 55.03 cM
• Pathway: Mineral absorption, organism-specific biosystem; Mineral absorption, conserved biosystem
• Function: ferric iron binding; ferric iron transmembrane transporter activity; metal ion binding

Reviews

08/01/2020

Their team of experts is not only knowledgeable about the TF protein but is also dedicated to assisting researchers like myself in overcoming any challenges that may arise.

01/22/2018

This high-quality protein is crucial for the success of my experiments, ensuring that I obtain reliable and meaningful scientific findings.

04/11/2016

The TF protein is of exceptional quality, making it a perfect fit for my experimental needs.

Q&As

Can TF proteins be used for diagnosing diseases?

Yes, abnormalities in TF proteins can serve as diagnostic markers for certain diseases.

Are there any approved drugs that target TF proteins?

Yes, some drugs target TF proteins, especially in the treatment of cancer.

How do TF proteins contribute to autoimmune diseases?

TF proteins can trigger or suppress immune responses, making them relevant in understanding autoimmune diseases.

How do TF proteins play a crucial role in clinical applications?

TF proteins are vital for understanding disease mechanisms and can be targeted for therapeutic purposes.

Are there any clinical tests or assays that measure TF protein levels?

Yes, various assays, like ELISA and Western blot, can be used to quantify TF protein levels.