Native Chicken Serum Transferrin

• Cat.No.: TF-143C

Specification

• Description: Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 77 kDa and a serum concentration range of 1800 to 2700 mg/L. It is synthesized in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. Iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in hemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions.The function of transferrin is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. In addition to its function in iron transport, this protein may also have a physiologic role as granulocyte/pollen binding protein (GPBP) involved in the removal of certain organic matter/allergens from serum.
• Source: Purified from Chicken Serum
• Species: Chicken
• Form: Liquid
• Protein length: Full length native Chicken Serum Transferrin
• Purity: >95% (SDS-PAGE)
• Applications: Western blotting,ELISA,etc
• Storage: Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage Buffer: PBS
• Tag: Non

Gene Information

• Gene Name: TF transferrin (ovotransferrin) [ Gallus gallus ]
• Official Symbol: TF
• Synonyms: LTF; TFEW; conalbumin; ovotransferrin; lactotransferrin; serum transferrin; allergen Gal d III; ovotransferrin BB type; ovotransferrin BC type; ovotransferrin CC type
• Gene ID: 396241
• mRNA Refseq: NM_205304
• Protein Refseq: NP_990635
• UniProt ID: P02789
• Chromosome Location: chromosome: 9
• Function: ferric iron binding

Reviews

08/01/2020

Their team of experts is not only knowledgeable about the TF protein but is also dedicated to assisting researchers like myself in overcoming any challenges that may arise.

01/22/2018

This high-quality protein is crucial for the success of my experiments, ensuring that I obtain reliable and meaningful scientific findings.

04/11/2016

The TF protein is of exceptional quality, making it a perfect fit for my experimental needs.

Q&As

Can TF proteins be used for diagnosing diseases?

Yes, abnormalities in TF proteins can serve as diagnostic markers for certain diseases.

Are there any approved drugs that target TF proteins?

Yes, some drugs target TF proteins, especially in the treatment of cancer.

How do TF proteins contribute to autoimmune diseases?

TF proteins can trigger or suppress immune responses, making them relevant in understanding autoimmune diseases.

How do TF proteins play a crucial role in clinical applications?

TF proteins are vital for understanding disease mechanisms and can be targeted for therapeutic purposes.

Are there any clinical tests or assays that measure TF protein levels?

Yes, various assays, like ELISA and Western blot, can be used to quantify TF protein levels.