Native Human Transferrin
| Cat.No. : | TF-391H |
| Product Overview : | Native human TF was expressedin Human plasma,which having a molecule weight of 77 kDa. |
- Specification
- Gene Information
- Related Products
| Cat. No. : | TF-391H |
| Description : | TFis a monomeric glycoprotein found in plasma at an average concentration of 250mg/100 ml. The Holo form of TF is iron saturated and also calledSiderophilin. The specific iron-binding protein in plasma, it has a role inthe transportation and distribution of iron among the body organs, in ironmetabolism and prevention of iron loss via the kidneys. Stored in bone marrowas Tf-bound iron, it also possesses bacteriostatic and fungistatic activity.Clinically, decreases in TF are observed in congenital disorders, newborns,inflammatory diseases, hypoproteinemias and nephrotic syndrome; increases arefound in pregnancy, iron-deficiency anemias, and inoculation hepatitis. TF isrequired by all types of cells in cultures for maximal growth. It is,therefore, an important transport factor used in defined culture media. Eachhuman transferring molecule has the ability to carry two iron ions in theferric form (Fe3+). Dissolves in water at 10 mg per ml. Prepared from plasmashown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative foranti-HIV 1 & 2 by FDA approved tests. |
| Form : | Lyophilized power -Buffer: Ammonium Bicarbonate; pH 7.2. |
| Source : | Human plasma |
| Molecule Weight : | 77 kDa |
| Concentration : | Lyophilized |
| Purity : | >95% by SDS-PAGEanalysis |
| Storage : | When stored at-80°C, product is stable for 3 years from date of delivery. Avoid repeated freeze-thawcycles. |
| Pathways : | EPHBforward signaling; HIF-1-alpha transcription factor network; Hemostasis; Ironuptake and transport; Mineral absorption; Platelet activation; Plateletdegranulation; Response to elevated platelet cytosolic Ca2+; Transferrinendocytosis and recycling; Transmembrane transport of small molecules |
| Gene Name : | TF transferrin [ Homo sapiens] |
| Official Symbol : | TF |
| Synonyms : | TF; transferrin; TFQTL1;PRO1557; PRO2086; Transferrin; serotransferrin; DKFZp781D0156; siderophilin;OTTHUMP00000197155; beta-1 metal-binding globulin; Beta-1 metal-bindingglobulin; EC 3.4.21 |
| Gene ID : | 7018 |
| mRNA Refseq : | NM_001063 |
| Protein Refseq : | NP_001054 |
| MIM : | 190000 |
| UniProt ID : | P02787 |
| Chromosome Location : | 3q22.1 |
| Function : | ferriciron binding; metal ion binding; protein binding; ubiquitin protein ligasebinding |
Products Types
| ◆ Recombinant Protein | ||
| TF-551H | Recombinant Human TF Protein, His-tagged | +Inquiry |
| Tf-151R | Recombinant Rat Tf Protein, His-tagged | +Inquiry |
| TF-651H | Recombinant Human TF Protein, MYC/DDK-tagged | +Inquiry |
| Trf-148M | Recombinant Mouse Trf Protein, His-tagged | +Inquiry |
| TF-150P | Recombinant Pig TF Protein, His-tagged | +Inquiry |
| ◆ Native Protein | ||
| Tf-392R | Native Rat Transferrin | +Inquiry |
| TF-132B | Native Bovine Transferrin | +Inquiry |
| TF-143C | Native Chicken Serum Transferrin | +Inquiry |
| ◆ Lysates | ||
| TF-1554SCL | Recombinant Sus scrofa (Pig) TF cell lysate | +Inquiry |
| TF-1208MCL | Recombinant Mouse TF cell lysate | +Inquiry |
| TF-2542HCL | Recombinant Human TF cell lysate | +Inquiry |
| ◆ Assay kits | ||
| Kit-0813 | TF (Human) Chromogenic Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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