Native Rat Transferrin

• Cat.No.: TF-93R

Specification

• Description: Transferrin is a monomeric glycoprotein found in plasma at an average concentration of 250 mg/100ml. The specific iron-binding protein in plasma, it has a role in the transportation and distribution of iron among the body organs, in iron metabolism and in prevention of iron loss via the kidney. Stored in bone marrow as TF-bound iron, it also possesses bacteriostatic and fungistatic activity. Clinically, decreases in transferrin are observed in congenital disorders, newborns, inflammatory diseases, hypo-proteinemias and nephritic syndrome; increases are found in pregnancy, iron-deficiency anemias and inoculation hepatitis. Transferrin is required by all types of cells in cultures for maximal growth. It is, therefore, an important factor used in defined culture media.
• Source: Rat Plasma
• Species: Rat
• Form: Lyophilized
• Molecular Mass: 80.0 kDa
• Purity: Purity by SDS-PAGE: ≥98%
• Usage: For Research Use Only! Not For Use in Humans.
• Notes: Centrifuge the vial prior to opening
• Storage: -20°C
• Storage Buffer: Lyophilized from 20 mM Na phosphate, pH 7.4 and 150 mM NaCI.
• Shipping: Gel pack
• Tag: Non

Gene Information

• Gene Name: Tf transferrin [ Rattus norvegicus ]
• Official Symbol: TF
• Synonyms: TF; transferrin; serotransferrin; siderophilin; beta-1 metal-binding globulin; liver regeneration-related protein LRRG03; Tfn; Trf; MGC93500
• Gene ID: 24825
• mRNA Refseq: NM_001013110
• Protein Refseq: NP_001013128
• Pathway: Mineral absorption, organism-specific biosystem; Mineral absorption, conserved biosystem
• Function: ferric iron binding; ferric iron transmembrane transporter activity; metal ion binding

Reviews

08/01/2020

Their team of experts is not only knowledgeable about the TF protein but is also dedicated to assisting researchers like myself in overcoming any challenges that may arise.

01/22/2018

This high-quality protein is crucial for the success of my experiments, ensuring that I obtain reliable and meaningful scientific findings.

04/11/2016

The TF protein is of exceptional quality, making it a perfect fit for my experimental needs.

Q&As

Can TF proteins be used for diagnosing diseases?

Yes, abnormalities in TF proteins can serve as diagnostic markers for certain diseases.

Are there any approved drugs that target TF proteins?

Yes, some drugs target TF proteins, especially in the treatment of cancer.

How do TF proteins contribute to autoimmune diseases?

TF proteins can trigger or suppress immune responses, making them relevant in understanding autoimmune diseases.

How do TF proteins play a crucial role in clinical applications?

TF proteins are vital for understanding disease mechanisms and can be targeted for therapeutic purposes.

Are there any clinical tests or assays that measure TF protein levels?

Yes, various assays, like ELISA and Western blot, can be used to quantify TF protein levels.