TNFa

  • Official Full Name

    tumor necrosis factor a (TNF superfamily, member 2)

  • Overview

    Tumor necrosis factor is a cytokine involved in systemic inflammation and is a member of a group of cytokines that all stimulate the acute phase reaction. TNF is mainly secreted by macrophages. TNF causes apoptotic cell death, cellular proliferation, differentiation, inflammation, tumorigenesis and viral replication, TNF is also involved in lipid metabolism, and coagulation. TNF's primary role is in the regulation of immune cells. Dysregulation and, in particular, overproduction of TNF have been implicated in a variety of human diseases- autoimmune diseases, insulin resistance, and cancer.
  • Synonyms

    TNFa; TNF; tumor necrosis factor (TNF superfamily, member 2); Cachectin; DIF; OTTHUMP00000029281; OTTHUMP00000037669; TNF-a; TNF-alpha; TNFA; TNFSF2; APC1 protein; TNF superfamily, member 2; TNF, macrophage-derived; TNF, monocyte-derived; Tumor necrosis factor ligand superfamily member 2; tumor necrosis factor alpha;

  • Recombinant Proteins
  • Atlantic Salmon
  • Guinea Pig
  • Human
  • Mouse
  • Ovine
  • Pig
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • Yeast
  • GST
  • His
  • Met
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TNF-39H Active Recombinant Human TNFa HEK293 N/A
Human TNFA-3314H Recombinant Human TNFA, His-tagged E.coli His 1-233aa
Human TNFa-39H Recombinant Human TNF alpha Yeast N/A
Human TNFA-1260H Recombinant Human TNFA protein E.coli N/A
Human TNFA-386H Recombinant Human TNFA protein, GST-tagged E.coli GST 77-233 aa
Human TNFA-344H Recombinant Human TNFA Protein, Met-tagged, Biotinylated E.coli Met Val77-Leu233
Human TNFA-1250H Recombinant Human TNFA protein, GST-tagged E.coli GST
Mouse TNFa-731M Active Recombinant Mouse TNFa Protein, Met-tagged E.coli Met Leu 80-Leu 235
Mouse TNFa-731MB Recombinant Mouse TNFa Protein, Met-tagged, Biotinylated E.coli Met Leu80-Leu235
Mouse mouse Tnfa-2639H Recombinant Mouse Tnfa protein, His-tagged E.coli His 1-235 aa
Atlantic Salmon TNFa-4389A Recombinant Atlantic Salmon TNFa Protein Yeast N/A 152aa
Guinea Pig TNFa-34G Recombinant Guinea Pig TNF alpha Yeast N/A
Ovine TNFa-89O Recombinant Ovine TNF alpha Yeast N/A
Zebrafish TNFA-12120Z Recombinant Zebrafish TNFA Mammalian Cell His
Zebrafish tnfa-3673Z Recombinant Zebrafish tnfa protein, His-tagged E.coli His 59-234aa
Zebrafish tnfa-4382Z Recombinant Zebrafish tnfa Protein Yeast N/A 148aa
Zebrafish tnfa-439Z Recombinant Zebrafish tnfa Protein, His-tagged E.coli N-His Ala88-Leu234
Pig TNFa-70P Recombinant Porcine TNFa E.coli N/A
Pig TNFa-24S Recombinant Swine TNF alpha Yeast N/A
  • Other Resource
  • TNFa Related Signal Pathway

TNFa involved in several pathways and played different roles in them. We selected most pathways TNFa participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TNFa were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

TNFa has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by TNFa itself. We selected most functions TNFa had, and list some proteins which have the same functions with TNFa. You can find most of the proteins on our site.

Function Related Protein

TNFa has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TNFa here. Most of them are supplied by our site. Hope this information will be useful for your research of TNFa.

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