| Description : |
TNFRSF21, also known as tumor necrosis factor receptor superfamily member 21, is a transmembrane protein in the TNF receptor superfamily. It promotes apoptosis through the activation of NF-kappa-B pathway. Binding of N-terminal APP (N-APP) and TNFRSF21 triggers caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6). This protein plays a role in signaling cascades triggered by stimulation of T-cell receptor. |
| Source : |
Insect cell |
| Species : |
Human |
| Tag : |
hIgG-His |
| Form : |
Liquid |
| Molecular Mass : |
60.4 kDa |
| AASequence : |
QPEQKASNLIGTYRHVDRATGQVLT CDKCPAGTYVSEHCTNTSLRVCSSC PVGTFTRHENGIEKCHDCSQPCPWP MIEKLPCAALTDRECTCPPGMFQSN ATCAPHTVCPVGWGVRKKGTETEDV RCKQCARGTFSDVPSSVMKCKAYTD CLSQNLVVIKPGTKETDNVCGTLPS FSSSTSPSPGTAIFPRPEHMETHEV PSSTYVPKGMNSTESNSSASVRPKV LSSIQEGTVPDNTSSARGKEDVNKT LPNLQVVNHQQGPHHRHILKLLPSM EATGGEKSSTPIKGPKRGHPRQNLH KHFDINEHLEPKSCDKTHTCPPCPA PELLGGPSVFLFPPKPKDTLMISRT PEVTCVVVDVSHEDPEVKFNWYVDG VEVHNAKTKPREEQYNSTYRVVSVL TVLHQDWLNGKEYKCKVSNKALPAP IEKTISKAKGQPREPQVYTLPPSRD ELTKNQVSLTCLVKGFYPSDIAVEW ESNGQPENNYKTTPPVLDSDGSFFL YSKLTVDKSRWQQGNVFSCSVMHEA LHNHYTQKSLSLSPGKHHHHHH |
| N-terminal Sequence Analysis : |
Gln 42 |
| Endotoxin : |
< 1.0 EU per 1 μg of protein (determined by LAL method) |
| Purity : |
> 85% by SDS - PAGE |
| Storage : |
Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
| Concentration : |
1.0 mg/mL (determined by Absorbance at 280nm) |
| Storage Buffer : |
In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol, 0.1mM PMSF. |
| Warning : |
For research use only. This product is not intended or approved for human, diagnostics or veterin |
