Recombinant Human TNFRSF21, Fc Chimera

• Cat.No.: TNFRSF21-50H
• Product Overview: Produced in HEK 293 cells. The extracellular domain of human DR6 (aa 1 - 212) is fused to the Fc portion of human IgG1.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Protein Length: 1-212 a.a.
• Description: uman DR6 (Death Receptor-6; TNFRSF21) is a type I transmembrane protein containing cytoplasmic death domain, member of the TNF receptor superfamily, expressed in most human tissues.
• Applications: The recombinant human DR6/Fc chimera can be used as a control for anti-human DR6 antibodies in amounts 15-50 ng.
• Usage: For research use only. Not for drug, diagnostic or other use.
• Notes: Indicated dilutions are recommended starting points for use of this product. Working concentrations should be determined by the investigator.

Gene Information

• Gene Name: TNFRSF21 tumor necrosis factor receptor superfamily, member 21 [ Homo sapiens ]
• Official Symbol: TNFRSF21
• Synonyms: TNFRSF21; tumor necrosis factor receptor superfamily, member 21; tumor necrosis factor receptor superfamily member 21; CD358; death receptor 6; DR6; TNFR-related death receptor 6; BM-018; MGC31965
• Gene ID: 27242
• mRNA Refseq: NM_014452
• Protein Refseq: NP_055267
• MIM: 605732
• UniProt ID: O75509
• Chromosome Location: 6p21.1
• Pathway: Apoptosis, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; PPARA Activates Gene Expression, organism-specific biosystem
• Function: protein binding; receptor activity