Active Recombinant Human TNFRSF21 protein, hFc-tagged

• Cat.No.: TNFRSF21-687H
• Product Overview: Active Recombinant Human TNFRSF21 protein(Met 1-Leu 350)(NP_055267.1) precursor was expressed in HEK293 with the fused Fc region of human IgG1 at the C-terminus.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Protein Length: 1-350 aa
• Form: Lyophilized from sterile PBS, pH 7.4.
• Bio-activity: Measured by its binding ability in a functional ELISA. Immobilized recombinant human DR6-Fc at 10 μg/mL (100 μl/well) can bind biotinylated human APP-Fc with a linear range of 0.03-0.25 μg/mL.
• Molecular Mass: The recombinant human DR6/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 547 amino acids and predicts a molecular mass of 60.3 kDa. By SDS-PAGE under reducing conditions, the apparent molecular mass of rhDR6/Fc monomer is approximately 95-100 kDa due to the glycosylation.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: > 95 % as determined by SDS-PAGE
• Storage: Store it under sterile conditions at -20°C to -80°C upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: TNFRSF21 tumor necrosis factor receptor superfamily, member 21 [ Homo sapiens ]
• Official Symbol: TNFRSF21
• Synonyms: TNFRSF21; tumor necrosis factor receptor superfamily, member 21; tumor necrosis factor receptor superfamily member 21; CD358; death receptor 6; DR6; TNFR-related death receptor 6; BM-018; MGC31965
• Gene ID: 27242
• mRNA Refseq: NM_014452
• Protein Refseq: NP_055267
• MIM: 605732
• UniProt ID: O75509