unc5c
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  • Official Full Name
  • unc-5 homolog C (C. elegans)
  • Background
  • This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region.
  • Synonyms
  • UNC5C; unc-5 homolog C (C. elegans); unc5 (C.elegans homolog) c; netrin receptor UNC5C; UNC5H3; homolog of C. elegans transmembrane receptor Unc5; Protein unc 5 homolog C; Unc 5 homolog 3; Unc 5 homolog C; unc-5 homolog 3; OTTHUMP00000161619; OTTHUMP00000219358; protein unc-5 homolog 3; protein unc-5 homolog C
Cat.#:UNC5C-633HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human UNC5C Protein, MYC/DDK-tagged
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Cat.#:UNC5C-1072HTag:Fc
Source (Host):NSO CellsSpecies:Human
Product nameRecombinant Human UNC5C Protein, Fc Chimera
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Cat.#:UNC5C-3599HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human UNC5C, GST-tagged
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Cat.#:UNC5C-17849MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse UNC5C Protein
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Cat.#:UNC5C-6452RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat UNC5C Protein
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Cat.#:UNC5C-6021CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken UNC5C
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Cat.#:UNC5C-5796ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish UNC5C
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Involved Pathway

UNC5C involved in several pathways and played different roles in them. We selected most pathways UNC5C participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with UNC5C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Axon guidance
KRAS; SEMA5A; AGRN; EPHB6; SEMA6B; EFNA2A; PLXND1; CDC42; EFNB3; GPC1B

Protein Function

UNC5C has several biochemical functions, for example, netrin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UNC5C itself. We selected most functions UNC5C had, and list some proteins which have the same functions with UNC5C. You can find most of the proteins on our site.
Function
Related Protein
Function netrin receptor activity
Related Protein Unc5b; UNC5C