USP8

  • Official Full Name

    ubiquitin specific peptidase 8

  • Overview

    Ubiquitinating enzymes (UBEs) catalyze protein ubiquitination, a reversible process countered by deubiquitinating enzyme (DUB) action. Five DUB subfamilies are recognized, including the USP, UCH, OTU, MJD and JAMM enzymes. The deubiquitinating enzyme, ubi
  • Synonyms

    USP8; ubiquitin specific peptidase 8; ubiquitin specific protease 8; ubiquitin carboxyl-terminal hydrolase 8; HumORF8; KIAA0055; UBPY; hUBPy; ubiquitin isopeptidase Y; ubiquitin thioesterase 8; deubiquitinating enzyme 8; ubiquitin thiolesterase 8; ubiquit;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Sf9 Insect Cell
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|SUMO
  • Myc
  • DDK
  • N/A
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human USP8-127H Active Recombinant Human USP8 E.coli N/A
Human USP8-86H Active Recombinant Human USP8, FLAG-tagged Sf9 Insect Cell Flag
Human USP8-161H Recombinant Human USP8, His & SUMO-tagged E.coli His/SUMO
Human USP8-162H Recombinant Human USP8, His-tagged E.coli His
Human USP8-451HCL Recombinant Human USP8 293 Cell Lysate HEK293 N/A
Human USP8-301310H Recombinant Human USP8 protein, GST-tagged E.coli GST Ser15-Val253
Human USP8-3738H Recombinant Human USP8 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human USP8-0543H Recombinant Human USP8 Protein (A182-T318), His tagged E.coli His A182-T318
Human USP8-0544H Recombinant Human USP8 Protein (A182-T318), Tag Free E.coli No tag A182-T318
Human USP8-3938H Recombinant Human USP8 protein, His-tagged E.coli His 15-253 aa
Human USP8-1411H Recombinant Human USP8 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human USP814976H Recombinant Human USP8 (734-1110) Protein
Mouse Usp8-6883M Recombinant Mouse Usp8 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque USP8-5132R Recombinant Rhesus monkey USP8 Protein, His-tagged Mammalian Cell His
Rhesus Macaque USP8-4945R-B Recombinant Rhesus Macaque USP8 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque USP8-4945R Recombinant Rhesus Macaque USP8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

USP8 involved in several pathways and played different roles in them. We selected most pathways USP8 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with USP8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
EndocytosisSNX32;IL2RGA;GIT2B;BF2;SMAP2;IL2RB;ARAP2;HRASA;SNF8

USP8 has several biochemical functions, for example, SH3 domain binding, cysteine-type endopeptidase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by USP8 itself. We selected most functions USP8 had, and list some proteins which have the same functions with USP8. You can find most of the proteins on our site.

Function Related Protein
SH3 domain bindingSH3BP5;PTTG2;ZFP106;LRP2;FAM125A;TOM1L1;CRB3;VASPA;QKIA
cysteine-type endopeptidase activityCASP8L1;CTSBA;USP5;USP9;USP49;CASPB;CTSSB.2;CTSJ;ATG4B
protein bindingTPP2;RUNX1T1;IRAK1;ZNF131;P4HB;CSK;SRGAP1;DDOST;C4orf46
ubiquitin-specific protease activitySTAMBP;USP42;USP9;USP31;YOD1;USP50;OTUD3;OTUB1A;USP9X

USP8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with USP8 here. Most of them are supplied by our site. Hope this information will be useful for your research of USP8.

YWHAZ; CHMP1B; YWHAB; Grap2; CHMP1A; CHMP4C

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