Active Recombinant Human USP8
Cat.No. : | USP8-127H |
Product Overview : | Recombinant Human USP8 was expressed in E.coli |
- Specification
- Gene Information
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Description : | Ubiquitin carboxyl-terminal hydrolase 8 is an enzyme that in humans is encoded by the USP8 gene. |
Source : | E. coli |
Species : | Human |
Form : | 50 mM HEPES pH 7.5, 150 mM sodium chloride, 2 mM dithiothreitol, 10% glycerol |
Bio-activity : | Deubiquitylase Enzyme Assay: The activity of USP8 was validated by determining the increase in fluorescence measured as a result of the enzyme catalysed cleavage of the fluorogenic substrate Ubiquitin-Rhodamine110-Glycine generating Ubiquitin and Rhodamine110-Glycine. Incubation of the substrate in the presence or absence of USP8 was compared confirming the deubiquitylating activity of USP8. |
Molecular Mass : | ~128kDa |
Purity : | >66% by InstantBlue™ SDS-PAGE |
Storage : | 12 months at -70℃; aliquot as required. |
Concentration : | 0.5 mg/ml |
Gene Name : | USP8 ubiquitin specific peptidase 8 [ Homo sapiens ] |
Official Symbol : | USP8 |
Synonyms : | USP8; ubiquitin specific peptidase 8; ubiquitin specific protease 8; ubiquitin carboxyl-terminal hydrolase 8; HumORF8; KIAA0055; UBPY; hUBPy; ubiquitin isopeptidase Y; ubiquitin thioesterase 8; deubiquitinating enzyme 8; ubiquitin thiolesterase 8; ubiquitin-specific-processing protease 8; FLJ34456; MGC129718; |
Gene ID : | 9101 |
mRNA Refseq : | NM_001128610 |
Protein Refseq : | NP_001122082 |
MIM : | 603158 |
UniProt ID : | P40818 |
Chromosome Location : | 15q21.1 |
Pathway : | Downregulation of ERRB2:ERBB3 signaling, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; ErbB2/ErbB3 signaling events, organism-specific biosystem; Internalization of ErbB1, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by ERBB2, organism-specific biosystem; |
Function : | SH3 domain binding; cysteine-type endopeptidase activity; peptidase activity; protein binding; ubiquitin thiolesterase activity; ubiquitin-specific protease activity; |
Products Types
◆ Recombinant Protein | ||
USP8-0543H | Recombinant Human USP8 Protein (A182-T318), His tagged | +Inquiry |
USP8-0544H | Recombinant Human USP8 Protein (A182-T318), Tag Free | +Inquiry |
USP8-4945R | Recombinant Rhesus Macaque USP8 Protein, His (Fc)-Avi-tagged | +Inquiry |
Usp8-6883M | Recombinant Mouse Usp8 Protein, Myc/DDK-tagged | +Inquiry |
USP8-301310H | Recombinant Human USP8 protein, GST-tagged | +Inquiry |
◆ Lysates | ||
USP8-451HCL | Recombinant Human USP8 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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